Sedation Drugs for ICU Patients Handout
You also want an ePaper? Increase the reach of your titles
YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.
General Tips
• Analagosedation is a common approach to treat pain and to keep the patient sedated in the ICU
• Suggested to target light sedation (RASS -1 to 0), utilizing a sedation free period to assess level of sedation is beneficial
• Maintain a MAP of ≥65 mmHg
• For continuous infusion, have orders in for PRN boluses for management of breakthrough pain/agitation (midazolam/lorazepam, fentanyl/morphine), can
use boluses from the bag
• Propofol/dexmedetomidine is recommended over benzodiazepines as they have shown quicker time to light sedation and quicker time to extubation.
Benzodiazepines have potential to contribute to delirium as well
o Propofol and dexmedetomidine have been compared to each other with no noted clinically significant difference
• Patients may require more than one medication depending on their response and target level of sedation/pain control
• Pain, Agitation, Delirium, Immobility, and Sleep (PADIS) guidelines
• For patients on paralytics, both a pain medication and a sedative (not dexmedetomidine) are required. No sedation vacation is performed
Change language