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Specific breed brochure - Breed Nutrition

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<strong>Nutrition</strong> formulated<br />

to support joint health<br />

Around 40% of large dogs aged upwards of seven years old suffer from arthritis (Deeb and Wolf,<br />

1994), particularly those with dysplasia or osteochondritis and those that practised a physical activity<br />

at too young an age or too intensely, causing repeated microtraumas to joint cartilage.<br />

<strong>Nutrition</strong> is a way of providing substances that help maintain joint health. They can stimulate the<br />

regeneration of cartilage cells (glucosamine* and chondroitin*) and promote cartilage hydration.<br />

Glucosamine and chondroitin sulphate<br />

is a synergistic mix that helps support cartilage health<br />

Rottweiler 26 contains a high level (1200 mg per kg) of chondroitin sulphate and glucosamine,<br />

natural substances that help maintain the health of joints and cartilage (Johnston et al, 2001).<br />

These substances belong to the glycosaminoglycan family (GAGs), natural components of cartilage.<br />

GAGs facilitate the hydration of cartilage, which helps it fulfil its role as a shock absorber. They<br />

are also present in synovial fluid, helping lubricate the joints.<br />

glucosamine and chondroitin sulphate are given to dogs to help<br />

Structure of a joint cavity<br />

maintain joint health and mobility.<br />

1. Synovial fluid<br />

2. Synovial membrane<br />

3. Joint cartilage<br />

The joint is protected by a capsule lined with the synovial<br />

membrane, which secretes the fluid needed to nourish<br />

cartilage. After oral administration, glucosamine and<br />

chondroitin are concentrated in the synovial fluid.<br />

- Glucosamine is precursor of many components of cartilage.<br />

After oral administration it is concentrated in the joints<br />

(Davidson et al, 2000), where it stimulates the regeneration of<br />

cartilage, particularly by promoting the synthesis of collagen.<br />

(Braham et al, 2003).<br />

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