[libribook.com] Traumatic Scar Tissue Management 1st Edition

Silverstein 1992, Leproult et al. 1997, Vgontzas et al. 1999, Cole-King &
Harding 2001, Rose et al. 2001, Irwin 2002, Christian et al. 2006, Posthauer
2006, Bosch et al. 2007, Lucas 2011, House 2015).
According to Christian and co-workers (Christian et al. 2006):
Greater exploration of the role of glucocorticoids, GH, oxytocin, and other
hormones/growth factors will provide a clearer understanding of the
multiple biological pathways by which stress affects healing. Similarly, we
know that the nervous system substantially influences healing. However,
little attention has been paid to delineating the influences of stress on the
nerves in injured tissue, but it would be no surprise to discover that their
neuropeptides and neurotransmitters play an important role in the stresshealing
link.
During trauma, mechanoreceptors are subjected to harsh treatment and may react
to strong mechanical force by relaying incoherent or misinformation to local,
regional, or central nerve centers. The various nerve centers may under- or
overestimate the mechanical stimuli information during truamtic events, and
nerve receptors can become confused by the milieu of the traumatic insults
occurring simultaneously (Barral & Croibier 1999).