[libribook.com] Traumatic Scar Tissue Management 1st Edition

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Figure 6.1Depth of burn trauma and structures impacted.Dermal water plays an important role in maintaining the physical properties ofthe skin (e.g. moisturizing and elasticity) (Nakagawa et al. 2010). Specializedcells in the dermis assist with regulating temperature and fighting infection. Thedermis also houses vessels that supply blood and nutrients to the skin. Damageto the sweat glands, sebaceous glands, hair follicles, nerve receptors, bloodvessels, lymph nodes/vessels, muscle and connective tissue may occur.Partial-thickness burn injuries can be extremely painful, are often accompaniedby blistering and edema/swelling, and may require debridement (removal oflacerated, weaken, debilitated or contaminated tissue) or skin grafting(transplanted tissue). Depending on the type of skin graft needed, the donor sitemay lose the epidermis and part or all of the dermis.Third DegreeThird degree trauma involves destruction of all epidermal and dermal layers andis commonly referred to as a ‘full-thickness’ injury. Damage extends below hairfollicles and sweat glands, into the subcutaneous tissue (i.e. connective tissue(CT) layer that is seeded with adipocytes).With full-thickness trauma, there may be extensive edema and skincharacteristics can change dramatically (e.g. charred, leathery appearance). Thirddegree injuries are usually not painful because of the destruction of nerveendings. Skin grafting or other replacement options are often required.Fourth DegreeFourth degree trauma involves destruction of epidermis, dermis, subcutaneoustissue, ligaments, tendons, nerves, blood vessels, possibly down to the level ofbone. Fourth degree trauma often leads to amputation and significant functionalimpairment. Skin grafting and multistage reconstructive procedures arenecessary.

Sequelae and ComplicationsA critical burn injury is a unique trauma that often is accompanied by significantmetabolic disturbances as well as a change in the normal state of innate andadaptive immunity (Shankar et al. 2007). Human skin acts as a blockade againstenvironmental insults and against colonization of pathogenic microbes, and isalso an immune organ with significant surveillance and thermoregulatoryfunctions. This knowledge helps us to understand that the loss of large portionsof skin as the result of burns results in impaired immunity, metaboliccompromises, fluid shifts, and heat loss (Shankar et al. 2007).Burn injuries can cause severe muscle loss, muscle weakness, contractures, andtraumatic scars, leading to lifelong physical impairments (Diego et al. 2013).Severe burns may require the removal of the dermal layer and subsequent skingraft procedure(s) (Ganio et al. 2013).Burn injury sequelae can occur as a result of scarring associated with the burntrauma or graft proceedures.Traumatic ScarsHypertrophic scarring is the most common type of scar tissue formed after aburn injury. Hypertrophic scars are formed in 30–72% of burn survivors afterinjury. In addition to the above noted risk factors, hypertrophic scar developmentassociated with burn injuries is mainly influenced by wound healing time(delayed 3 weeks or more), the depth (degree of injury), extent (size/surface areaaffected) and if multiple surgical or graft procedures are performed (Deitch et al.1983, Cubison et al. 2006, Thompson et al. 2013, Cho et al. 2014).Unfortunately, most of the published information on post-burn scarring does notaccurately define these factors and the body’s whirlpool of physiologicalresponses to burn injury continue to be studied and researched (Spurr &Shakespeare 1990, Bombaro et al. 2003, Cho et al. 2014).What do we know? Fibroblasts play a key role in wound healing and scarformation as they:• Actively release cytokines

Figure 6.1

Depth of burn trauma and structures impacted.

Dermal water plays an important role in maintaining the physical properties of

the skin (e.g. moisturizing and elasticity) (Nakagawa et al. 2010). Specialized

cells in the dermis assist with regulating temperature and fighting infection. The

dermis also houses vessels that supply blood and nutrients to the skin. Damage

to the sweat glands, sebaceous glands, hair follicles, nerve receptors, blood

vessels, lymph nodes/vessels, muscle and connective tissue may occur.

Partial-thickness burn injuries can be extremely painful, are often accompanied

by blistering and edema/swelling, and may require debridement (removal of

lacerated, weaken, debilitated or contaminated tissue) or skin grafting

(transplanted tissue). Depending on the type of skin graft needed, the donor site

may lose the epidermis and part or all of the dermis.

Third Degree

Third degree trauma involves destruction of all epidermal and dermal layers and

is commonly referred to as a ‘full-thickness’ injury. Damage extends below hair

follicles and sweat glands, into the subcutaneous tissue (i.e. connective tissue

(CT) layer that is seeded with adipocytes).

With full-thickness trauma, there may be extensive edema and skin

characteristics can change dramatically (e.g. charred, leathery appearance). Third

degree injuries are usually not painful because of the destruction of nerve

endings. Skin grafting or other replacement options are often required.

Fourth Degree

Fourth degree trauma involves destruction of epidermis, dermis, subcutaneous

tissue, ligaments, tendons, nerves, blood vessels, possibly down to the level of

bone. Fourth degree trauma often leads to amputation and significant functional

impairment. Skin grafting and multistage reconstructive procedures are

necessary.

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