[libribook.com] Traumatic Scar Tissue Management 1st Edition

16.06.2020 Views

Pathophysiological ConsiderationNeuroinflammation may play a role in the formation of hypertrophic scars,as a result of increased cellular proliferation, cytokine and growth factorstimulation and excess ECM deposition (Scott et al. 2007).

Pathophysiological ConsiderationNeuropeptides have a direct fibroblastic effect and undue mechanicalstretching of skin can lead to significant increase in neuropeptides (Scott etal. 2007, Cheng et al. 2011, Widgerow 2013).

Pathophysiological Consideration

Neuroinflammation may play a role in the formation of hypertrophic scars,

as a result of increased cellular proliferation, cytokine and growth factor

stimulation and excess ECM deposition (Scott et al. 2007).

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