[libribook.com] Traumatic Scar Tissue Management 1st Edition

Pathophysiological consideration
Fibrosis is commonly considered to be a by-product of an abnormal or chronic inflammatory response as a result
of cumulative or overuse-type trauma, immobilization and poor wound healing. When not effectively managed,
fibrosis can result in a milieu of functional deficits. The fall-out from fibrosis include the following and associated
sequelae: increased risk of recurrent injury, muscle contraction dysfunction, altered force transmission, impaired
tissue; slide/glide and stretch, neural, circulatory and lymphatic compression, antalgia, pain and pain translation
(i.e. shift from acute to chronic pain) (Simons, Travell & Simons 1999, Gabbiani 2003, Shah et al. 2005, 2008,
Hinz 2007, Grinell 2008, Chiquet et al. 2009, Lowe 2009, Ciciliot & Schiaffino 2010).