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[libribook.com] Traumatic Scar Tissue Management 1st Edition

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Pathophysiological Consideration

When one brain hemisphere has been damaged, the intact hemisphere may

take over some of its functions. Compensation can also occur via

reorganization and formation of new connections between intact neurons.

The ‘rewiring’ of neuronal connection is stimulated by activity. For neurons

to form beneficial connections, they must be correctly stimulated.

Inappropriately stimulated, bored or unstimulated neurons will disengage or

find something else to do. Neuroplasticity can also result in an impairment

or harmful compensation; for example, some who are deaf may experience

tinnitus, thought to be the result of the rewiring of brain cells starved for

sound. Another illustration of this is neuroplastic pain – pain caused by or

increased as a result of changes within the NS. In addition to the higher

brain centers, neuroplastic changes can occur in the spinal cord and

periphery following injury and inflammation. Neuroplastic changes may

increase the magnitude of perceived sensation (pain) and may contribute to

pain translation (shift from acute pain to chronic/persistent pain) and

consequent increased sensitivity (Puretić & Demarin 2012).

Spinal Cord

The spinal cord propagates nerve impulses between the spinal nerves and the

brain, primarily functioning as a conduit for motor and sensory information, and

as a center for coordinating certain reflexes, which it can independently control.

Each of the 31 segments of the spinal cord comprises one pair of dorsal and

ventral horns:

• Ventral components: groups of efferent (out-going) motor neurons

• Dorsal components: groups of afferent (in-coming) sensory neurons (Zigmond

et al. 1999) (Fig. 4.2).

The spinal cord also contains interneurons which modulate bidirectional

information from the sensory and motor components.

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