[libribook.com] Traumatic Scar Tissue Management 1st Edition

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pro-collagen in the fibroblasts will change types (e.g., collagen type I intocollagen type III), or undifferentiated cell types may adapt towards a morefunctionally appropriate lineage (e.g. chondrocyte) (Benjamin & Ralphs, 1998,Bank et al. 1999, Jarvinen et al. 2002, Milz et al. 2005, Mammoto & Ingber2009). Therefore, a tissue that is exposed to unusual demand may remodel into aform or presentation that is atypical to its fundamental nature.

Clinical ConsiderationSignificant compression can ultimately culminate in tissues changing theirmorphology (e.g. tissue that was once populated with fibroblasts, becomesinvested predominately with chondrocytes – forming cartilage, along withits mineral deposition (Benjamin & Ralphs 1998, Bank et al. 1999). Theseadaptations have been demonstrated in the supraspinatus tendon (akacalcific tendonitis), transverse acetabular ligament, transverse ligament ofatlas, as well as various other ligaments and tendons throughout the body(Bank et al. 1999, Milz et al. 2005). What once was pliant mobile tissueexhibits entirely different functional capabilities and palpable feel (Kumka& Bonar 2012). Here we can envision the potential for unfavourableoutcomes as a result of improperly stimulated tissue during therepair/remodeling stage of healing.Timing is everything – more on this in Chapter 05.

pro-collagen in the fibroblasts will change types (e.g., collagen type I into

collagen type III), or undifferentiated cell types may adapt towards a more

functionally appropriate lineage (e.g. chondrocyte) (Benjamin & Ralphs, 1998,

Bank et al. 1999, Jarvinen et al. 2002, Milz et al. 2005, Mammoto & Ingber

2009). Therefore, a tissue that is exposed to unusual demand may remodel into a

form or presentation that is atypical to its fundamental nature.

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