[libribook.com] Traumatic Scar Tissue Management 1st Edition

16.06.2020 Views

Clinical ConsiderationChanges in fibroblast shape and subsequently function occurs in responseto a variety of signals, including mechanically applied tension or strain(Eagen et al. 2007, Mammoto & Ingber 2009, Stecco et al. 2009, Meltzeret al. 2009). This feature of fibroblasts enables fascia to alter its fiberconfiguration in response to mechanical demands or stress placed upon it(e.g. movement, exercise, posture, work-related activities). Additionally,this provides a plausible explanation for the mechanism by which fascialspecific therapies (e.g. structural integration/Rolfing, myofascial massageand acupuncture) produce therapeutic results (Langevin et al. 2004).

Clinical ConsiderationManual therapy techniques treat the fascial layers by altering density,tonus, viscosity and the arrangement of fascia (Findley et al. 2012).Myofibroblasts (MFBs): differentiation of fibroblasts into MFBs is triggered inresponse to mechanical strain/tensional loading and certain cytokines (e.g.transforming growth factor beta-1; TGF-β1). MFBs play an important role ininflammation, remodeling and fibrosis (Cathie 1974, Powell et al. 1999,Tomasek et al. 2002, Hinz & Gabbiani 2003, Schleip et al. 2007, Nekouzadeh etal. 2008, Hinz 2013).

Clinical Consideration

Changes in fibroblast shape and subsequently function occurs in response

to a variety of signals, including mechanically applied tension or strain

(Eagen et al. 2007, Mammoto & Ingber 2009, Stecco et al. 2009, Meltzer

et al. 2009). This feature of fibroblasts enables fascia to alter its fiber

configuration in response to mechanical demands or stress placed upon it

(e.g. movement, exercise, posture, work-related activities). Additionally,

this provides a plausible explanation for the mechanism by which fascial

specific therapies (e.g. structural integration/Rolfing, myofascial massage

and acupuncture) produce therapeutic results (Langevin et al. 2004).

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