Open Access e-Journal Cardiometry No.16 May 2020
We should mention that Cardiometry is a fine diagnostics tool to assess heart life expectancy. Our experts, using Cardiocode in “red zones” in intensive care units, have confirmed effectiveness of noninvasive measuring of the hemodynamics data on the cardiovascular system performance in critical patients with different severity degrees. The medical staff involved had a possibility not only to monitor the state in each critical patient, but also to predict and control the progression of a disease. We are going to publish some results of this pilot study in our next issues. We should mention that Cardiometry is a fine diagnostics tool to assess heart life expectancy. Our experts, using Cardiocode in “red zones” in intensive care units, have confirmed effectiveness of noninvasive measuring of the hemodynamics data on the cardiovascular system performance in critical patients with different severity degrees. The medical staff involved had a possibility not only to monitor the state in each critical patient, but also to predict and control the progression of a disease. We are going to publish some results of this pilot study in our next issues.
13. Rose G. Variability of angina. Some implicationsfor epidemiology. British journal of preventive & socialmedicine. 1968;22(1):12.14. Rahman MA, Spurrier N, Mahmood MA, RahmanM, Choudhury SR, Leeder S. Rose Angina Questionnaire:validation with cardiologists' diagnoses todetect coronary heart disease in Bangladesh. indianheart journal. 2013;65(1):30-9.15. Bastos M-S, Lotufo PA, Whitaker AL, Bensenor IM.Validation of the short-version of Rose Angina Questionnairein Brazil. Arq Bras Cardiol. 2012;99(5):1056-9.16. Kannel WB, D'Agostino RB, Wilson PW, BelangerAJ, Gagnon DR. Diabetes, fibrinogen, and risk ofcardiovascular disease: the Framingham experience.American heart journal. 1990;120(3):672-6.17. Ford ES, Zhao G, Li C. Pre-diabetes and the risk forcardiovascular disease: a systematic review of the evidence.Journal of the American College of Cardiology.2010;55(13):1310-7.18. Zhou B, Lu Y, Hajifathalian K, Bentham J, Di CesareM, Danaei G, et al. Worldwide trends in diabetessince 1980: a pooled analysis of 751 population-basedstudies with 4· 4 million participants. The Lancet.2016;387(10027):1513-30.19. Grundy SM, Benjamin IJ, Burke GL, Chait A, EckelRH, Howard BV, et al. Diabetes and cardiovasculardisease: a statement for healthcare professionalsfrom the American Heart Association. Circulation.1999;100(10):1134-46.20. Habibian S, Eyni E, Emami H, Azizi F. Prevalenceof Rose Questionnaire Angina and It's AssociationWith Coronary Heart Disease Risk Factors In Tehran,IR Iran. 2000.21. Fakhrzadeh H, Nabipour I, Dehdari A. The associationof hypertension and ischemic heart disease; apopulation-based study. 2001.22. Sadeghi M, Rouhafza H, Shirani S, AKHAVANTA, Aghdak P, Hosseini S. The prevalence of coronaryartery disease according to Rose Questionnaire andECG: Isfahan Healthy Heart Program (IHHP). 2006.23. Poudel M, Bhandari R, Malla G, Baral D, UpretyS, Chaudhary R, et al. Rose Angina Questionnaire:Validation in emergency department to detect myocardialinfarction in a tertiary hospital of easternNepal. Hong Kong Journal of Emergency Medicine.2019:1024907919836573.24. Hui G, Koch B, Calara F, Wong ND. Angina in coronaryartery disease patients with and without diabetes:US National Health and Nutrition Examination Survey2001–2010. Clinical cardiology. 2016;39(1):30-6.25. Park G-M, An H, Lee S-W, Cho Y-R, Gil EH, HerSH, et al. Risk score model for the assessment of coronaryartery disease in asymptomatic patients with type2 diabetes. Medicine. 2015;94(4).116 | Cardiometry | Issue 16. May 2020
ORIGINAL RESEARCH Submitted: 4.12.2019; Accepted: 20.02.2020; Published online: 21.05.2020Effects produced by automatedplasmapheresis onmorphofunctional data oncardiovascular system performancein ischemic heart disease patientsYury E. Malchevsky 1 *, Aligeidar A. Ragimov 21Federal Research Center "Krasnoyarsk Science Center of theSiberian Branch of the Russian Academy of Sciences",Research Institute for Medical Problems in the North (RIMPN)Russia, 660036, Krasnoyarsk, ul. Akademgorodok, 502I.M. Sechenov First Moscow State Medical University of theMinistry of Health of the Russian Federation(Sechenov University)Russia, 119435, Moscow, ul. Bolshaya Pirogovskaya, 2, str. 4*Corresponding author:e-mail: malchevskiyy@mail.ruAbstractWe have performed the study of the effects made by the automatedplasmapheresis application on ischemic heart diseaseclinical manifestations, echocardiographic indices and heart ratevariability in patients with exertional angina III-IV functional class.It has been found that the applied plasmapheresis method is capableto reduce the severity of the disease clinical manifestationsand improve the echocardiographic characteristics of the heart, inparticular, reduce the level of end-diastolic volume, and increaseejection fraction. The clinical effect is already apparent at the earlystages of the treatment and remains unchanged even after 6months thereof. Also revealed has been the normalization of heartrate variability, indicating a decreased activity of the sympatheticnervous system. It is concluded that the plasmapheresis methodcan be successfully used in practice by a wide range of hospitals,where patients with ischemic heart disease are monitored, includingthe ambulatory conditions.KeywordsExertional angina, Plasmapheresis, Echocardiography, Heartrate variability, Holter monitoringImprintYury E. Malchevsky, Aligeidar A. Ragimov. Effects produced byautomated plasmapheresis on morphofunctional data on car-diovascular system performance in ischemic heart disease patients.Cardiometry; Issue 16; May 2020; р.117-122; DOI: 10.12710/cardiometry.2020.16.117122; Available from: http://www.cardiometry.net/issues/no16-may-2020/complex-treatment-ofchronic-heart-failureIntroductionIt is well known that so far CVD and first of allischemic heart disease (IHD) remain the main causesof mortality of population in the Russian Federation[2]. In addition to the existing medication and a wideapplication of invasive methods for IHD treatment, forlast decades some methods of alternative treatmentshave being introduced into clinical practice for thissort of patients that includes the efferent therapy techniques[1, 3-5]. In this connection, we should mentionthat the problem of an adequate extracorporealassistance retains its topicality in the context of thecomplex treatment of ischemic heart disease becausethere are a number of factors as listed below: a highoccurrence rate of this pathology, the disease severity,some predictable complications, an increasing cohortof younger patients and resistance to medication dueto available metabolic disorders [2, 4, 12].One of the most pathogenetically substantiatedand, therefore, promising approaches to the treatmentof the patients with ischemic heart disease (IHD), inparticular exertional angina, is the use of plasmapheresis(PP). However, at the same time, there are onlysome fragmented single reports on capabilities of thisapproach, and there are no data on factors responsiblefor effects and determining efficacy of the plasmapheresismethod application; no works are available whichrelate to justification of the use of different modes ofPP application in CHF therapy.AimsThe aim is to study some effects produced by theautomated plasmapheresis (PP) technique on clinicalsigns in ischemic heart disease patients and on on instrumentallaboratory data on the cardiovascular systemperformanceMaterials and methodsThe study was carried out on the basis of the RussianInstitution for Medical Problems of the North Regionof the North Division of the Russian Academy of Med-Issue 16. May 2020 | Cardiometry | 117
- Page 67 and 68: Table 2No. of ind.BMIAge, yearsHb,
- Page 69 and 70: ORIGINAL RESEARCH Submitted: 18.03.
- Page 71 and 72: а) b)Figure 1. Fragments of the bl
- Page 73 and 74: а)b)cd)Figure 3. Fragments of seru
- Page 75 and 76: zation of the facias and add to the
- Page 77 and 78: PV5 - blood volume (part of SV), pu
- Page 79 and 80: Conflict of interestNone declared.A
- Page 81 and 82: Issue 16. May 2020 | Cardiometry |
- Page 83 and 84: the action of high level energy. Ac
- Page 85 and 86: Figure 5. Diagram of “a multipuls
- Page 87 and 88: REPORT Submitted: 25.02.2020; Accep
- Page 89 and 90: used to suppress this sort of noise
- Page 91 and 92: tion v[n] using HFF, then the final
- Page 93 and 94: jω jω jωZe ( ) = Xe ( ) H1( e )
- Page 95 and 96: Figure 4. Filtering of the ECG sign
- Page 97 and 98: Significant data have been obtained
- Page 99 and 100: REVIEW Submitted: 5.03.2020; Accept
- Page 101 and 102: companies have even made the implem
- Page 103 and 104: the evaluation of the item occurs.
- Page 105 and 106: XFig.1. Medical recommender system
- Page 107 and 108: System Using Collaborative Filterin
- Page 109 and 110: processing analysis, in particular
- Page 111 and 112: Statement on ethical issuesResearch
- Page 113 and 114: ORIGINAL RESEARCH Submitted: 12.01.
- Page 115 and 116: Table 1Descriptive statistics of pa
- Page 117: ison to non-diabetic patients but s
- Page 121 and 122: The data have been collected and th
- Page 123 and 124: It is known that the main mechanism
ORIGINAL RESEARCH Submitted: 4.12.2019; Accepted: 20.02.2020; Published online: 21.05.2020
Effects produced by automated
plasmapheresis on
morphofunctional data on
cardiovascular system performance
in ischemic heart disease patients
Yury E. Malchevsky 1 *, Aligeidar A. Ragimov 2
1
Federal Research Center "Krasnoyarsk Science Center of the
Siberian Branch of the Russian Academy of Sciences",
Research Institute for Medical Problems in the North (RIMPN)
Russia, 660036, Krasnoyarsk, ul. Akademgorodok, 50
2
I.M. Sechenov First Moscow State Medical University of the
Ministry of Health of the Russian Federation
(Sechenov University)
Russia, 119435, Moscow, ul. Bolshaya Pirogovskaya, 2, str. 4
*
Corresponding author:
e-mail: malchevskiyy@mail.ru
Abstract
We have performed the study of the effects made by the automated
plasmapheresis application on ischemic heart disease
clinical manifestations, echocardiographic indices and heart rate
variability in patients with exertional angina III-IV functional class.
It has been found that the applied plasmapheresis method is capable
to reduce the severity of the disease clinical manifestations
and improve the echocardiographic characteristics of the heart, in
particular, reduce the level of end-diastolic volume, and increase
ejection fraction. The clinical effect is already apparent at the early
stages of the treatment and remains unchanged even after 6
months thereof. Also revealed has been the normalization of heart
rate variability, indicating a decreased activity of the sympathetic
nervous system. It is concluded that the plasmapheresis method
can be successfully used in practice by a wide range of hospitals,
where patients with ischemic heart disease are monitored, including
the ambulatory conditions.
Keywords
Exertional angina, Plasmapheresis, Echocardiography, Heart
rate variability, Holter monitoring
Imprint
Yury E. Malchevsky, Aligeidar A. Ragimov. Effects produced by
automated plasmapheresis on morphofunctional data on car-
diovascular system performance in ischemic heart disease patients.
Cardiometry; Issue 16; May 2020; р.117-122; DOI: 10.12710/
cardiometry.2020.16.117122; Available from: http://www.
cardiometry.net/issues/no16-may-2020/complex-treatment-ofchronic-heart-failure
Introduction
It is well known that so far CVD and first of all
ischemic heart disease (IHD) remain the main causes
of mortality of population in the Russian Federation
[2]. In addition to the existing medication and a wide
application of invasive methods for IHD treatment, for
last decades some methods of alternative treatments
have being introduced into clinical practice for this
sort of patients that includes the efferent therapy techniques
[1, 3-5]. In this connection, we should mention
that the problem of an adequate extracorporeal
assistance retains its topicality in the context of the
complex treatment of ischemic heart disease because
there are a number of factors as listed below: a high
occurrence rate of this pathology, the disease severity,
some predictable complications, an increasing cohort
of younger patients and resistance to medication due
to available metabolic disorders [2, 4, 12].
One of the most pathogenetically substantiated
and, therefore, promising approaches to the treatment
of the patients with ischemic heart disease (IHD), in
particular exertional angina, is the use of plasmapheresis
(PP). However, at the same time, there are only
some fragmented single reports on capabilities of this
approach, and there are no data on factors responsible
for effects and determining efficacy of the plasmapheresis
method application; no works are available which
relate to justification of the use of different modes of
PP application in CHF therapy.
Aims
The aim is to study some effects produced by the
automated plasmapheresis (PP) technique on clinical
signs in ischemic heart disease patients and on on instrumental
laboratory data on the cardiovascular system
performance
Materials and methods
The study was carried out on the basis of the Russian
Institution for Medical Problems of the North Region
of the North Division of the Russian Academy of Med-
Issue 16. May 2020 | Cardiometry | 117
Change language