Potassium Channel

Potassium Channel
The ion channel is a cell-specific amphiphilic membrane integrin that selectively
interacts with ions through the side chain of the residue to exert a specific
permeability barrier function. Ion channels are closely related to a variety of life
activities and are also important targets for drug design. Since the use of cell patch
clamp and single-channel recording technology, artificial membrane ion channel
reconstruction technology, gene recombination technology, channel protein
separation, purification and other biochemical techniques have made the molecular
structure of many channel proteins gradually clear, and its cDNA has been cloned. It
is currently believed that the K+ channel is the most diverse ion channel in the ion
channel. The research results show that there are two families of K + channels, and
their structure and function are different.
Molecular biology and gene recombination techniques also provide an effective way
for the study of ion channels. X-ray crystallography provides a visual image for the
structural study of K+ channels. With the study of K+ channels, there are still some
issues to be further explored, such as subunit function, gene mutation and disease
inconsistency. Due to the complexity and diversity of the K+ channel itself, there are
certain limitations in the understanding of some K+ structures and functions.
Multidisciplinary cross-disciplinary research and advanced technical methods explore
the mechanisms of certain diseases or conditions. It is of great theoretical and
practical significance to explore the mechanisms of potassium channel in certain
diseases and research on K+ channels has received increasing attention in the life
sciences.