European Patent Bulletin 2012/09 - European Patent Office
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European Patent Bulletin 2012/09 - European Patent Office

European Patent Bulletin 2012/09 - European Patent Office European Patent Bulletin 2012/09 - European Patent Office

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(C07D) II.1(1) (54) VERBESSERTES VERFAHREN ZUR HER- STELLUNG VON LETROZOL UND ZWI- SCHENPRODUKTEN DAVON AN IMPROVED PROCESS FOR PREPARATION OF LETROZOLE AND ITS INTERMEDIATES PROCÉDÉ PERFECTIONNÉ DE PRÉPARA- TION DU LÉTROZOLE ET SES INTERMÉ- DIAIRES (73) Fresenius Kabi Oncology Limited, B- 310, Som Datt Chambers - I Bhikaji Cama Place, New Delhi 110 066, IN (72) SHRAWAT, Vimal, Kumar, Ghaziabad 201 010, IN SINGH, Jai, Pal, Ghaziabad 201 010, IN NAUTIYAL, Rajesh, Prasad, Ghaziabad 201 010, IN (74) Le Coupanec, Pascale A.M.P., Cabinet Nony 3, rue de Penthièvre, 75008 Paris, FR C07D 301/10 → (51) C07C 41/03 C07D 307/20 → (51) C11C 3/00 C07D 307/32 → (51) C07C 211/48 C07D 307/60 → (51) C07D 409/12 C07D 309/14 → (51) C07C 211/48 C07D 317/64 → (51) C07C 217/64 C07D 319/12 → (51) C11C 3/00 (51) C07D 333/16 (11) 2 228 372 B1 (25) En (26) En (21) 10156142.1 (22) 10.03.2010 (84) AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR (43) 15.09.2010 (30) 12.03.2009 US 402740 05.03.2010 US 718289 (54) Verfahren zur Herstellung von (S)-(+)-N- Methyl-3-(1-Naphthyloxy)-3-(2-Thienyl)- Propylamin mittels einer optisch aktiven Methylhydroxylaminopropanolverbindung als Zwischenprodukt Process for Preparing (S)-(+)-N-Methyl-3- (1-Naphthyloxy)-3-(2-Thienyl-Propylamine by using Optically Active Methylhydroxylaminopropanol Compound as an Intermediate Procédé de préparation de (S)-(+)-N- Methyl-3-(1-Naphthyloxy)-3-(2-Thienyl- Propylamine en utilisant un composant optique actif de Méthylhydroxylaminopropanol en tant qu'intermédiaire (73) SCI Pharmatech, Inc., Hai-Hu-Tsun Lu-Chu- Hsiang, Taoyuan, TW (72) CHEN, Bo-Feng, Taoyuan, TW YEH, Jinun-Ban, Taoyuan, TW WONG, Weichyun, Toayuan, TW LU, Feng-Ju, Taoyuan, TW (74) Jones, Helen M.M., Gill Jennings & Every LLP The Broadgate Tower 20 Primrose Street, London EC2A 2ES, GB C07D 401/02 → (51) C07D 211/58 C07D 401/04 → (51) C07D 213/75 C07D 401/06 → (51) C07D 211/58 C07D 401/12 → (51) A01N 43/40 C07D 401/12 → (51) C07D 209/42 C07D 401/12 → (51) C07D 211/58 Europäisches Patentblatt European Patent Bulletin Bulletin européen des brevets C07D 401/12 → (51) C07D 213/75 C07D 401/14 → (51) A61K 31/506 C07D 401/14 → (51) C07D 211/58 C07D 401/14 → (51) C07D 239/90 C07D 401/14 → (51) C09B 5/14 (51) C07D 403/04 (11) 2 123 649 B1 A61K 31/404 A61K 31/405 A61P 35/00 A61P 3/10 A61P 7/00 A61P 29/00 A61P 37/00 A61P 9/00 (25) Zh (26) En (21) 07817351.5 (22) 03.12.2007 (84) AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR (43) 25.11.2009 (86) CN 2007/071161 03.12.2007 (87) WO 2008/067756 2008/24 12.06.2008 (30) 04.12.2006 CN 200610098202 15.12.2006 CN 200610161220 (54) 3-PYRROLO-CYCLOHEXYLEN-2-DIHY- DROINDOLINONDERIVATE UND ANWEN- DUNGEN DAVON 3-PYRROLO-CYCLOHEXYLENE-2- DIHYDRO-INDOLINONE DERIVATIVES AND USES THEREOF DÉRIVÉS DE 3-PYRROLO-CYCLOHEXY- LÈNE-2-DIHYDRO-INDOLINONE ET UTILISATIONS DE CEUX-CI (73) Jiangsu Simcere Pharmaceutical R&D Co., Ltd., No. 12 Huayuan Road, Nanjing Jiangsu 210042, CN (72) TANG, Feng c/o JIANGSU SIMCERE PHAR- MACEUTICAL R&D CO., LTD., Nanjing Jiangsu 210042, CN SHEN, Han c/o JIANGSU SIMCERE PHAR- MACEUTICAL R&D CO., LTD, Nanjing Jiangsu 210042, CN JIN, Qiu c/o JIANGSU SIMCERE PHARMA- CEUTICAL R&D CO., LTD, Nanjing Jiangsu 210042, CN DING, Lei c/o JIANGSU SIMCERE PHARMA- CEUTICAL R&D CO., LTD, Nanjing Jiangsu 210042, CN YANG, Jie c/o JIANGSU SIMCERE PHAR- MACEUTICAL R&D CO., LTD, Nanjing Jiangsu 210042, CN YIN, Xiaojin c/o JIANGSU SIMCERE PHAR- MACETICAL R&D CO., LTD., Nanjing Jiangsu 210042, CN LU, Shiyue c/o JIANGSU SIMCERE PHAR- MACEUTICAL R&D CO., LTD., Nanjing Jiangsu 210042, CN (74) Kramer, Reinhold, Kramer - Barske - Schmidtchen Landsberger Strasse 300, 80687 München, DE (51) C07D 403/12 (11) 1 636 208 B1 C07D 417/12 A61K 31/401 A61K 31/4155 A61K 31/425 A61K 31/4965 (25) En (26) En (21) 04759362.9 (22) 09.04.2004 (84) AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR AL HR LT LV MK (43) 22.03.2006 (86) US 2004/011012 09.04.2004 (87) WO 2004/092162 2004/44 28.10.2004 (30) 11.04.2003 US 412600 23.10.2003 US 513765 P 658 Patente Patents Brevets (09/2012) 29.02.2012 (54) INHIBITOREN VON SERINPROTEASEN, INSBESONDERE HCV-NS3-NS4A-PRO- TEASE INHIBITORS OF SERINE PROTEASES, PARTICULARLY HCV NS3-NS4A PROTEASE INHIBITEURS DES SERINE PROTEASES, EN PARTICULIER DE LA PROTEASE NS3- NS4A DU VHC (73) VERTEX PHARMACEUTICALS INCOR- PORATED, 130 Waverly Street, Cambridge, MA 02139-4242, US (72) FARMER, Luc, J., Foxboro, MA 02035, US PERNI, Robert, P., Marlborough, MA 01752, US BHISETTI, Govinda, Rao, Lexington, MA 02421, US WILSON, Keith, P., La Jolla, CA 92037, US (74) Burrichter, Arwed Andreas, COHAUSZ & FLORACK Patent- und Rechtsanwälte Partnerschaftsgesellschaft Bleichstrasse 14, 40211 Düsseldorf, DE (60) 10178023.7 / 2 332 935 C07D 403/12 → (51) C07D 209/42 C07D 403/12 → (51) C07D 213/75 C07D 403/12 → (51) C07D 239/90 C07D 403/14 → (51) A61K 31/506 C07D 403/14 → (51) C07D 239/90 C07D 405/12 → (51) C07D 209/42 C07D 405/12 → (51) C07D 213/75 C07D 405/14 → (51) C07D 209/42 C07D 407/06 → (51) C11C 3/00 C07D 409/06 → (51) C07D 213/75 (51) C07D 409/12 (11) 2 176 255 B1 C07D 307/60 A61K 31/365 A61K 31/385 A61P 35/00 A61P 29/00 A61P 3/10 A61P 31/00 (25) En (26) En (21) 08783912.2 (22) 07.08.2008 (84) AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR (43) 21.04.2010 (86) CN 2008/071919 07.08.2008 (87) WO 2009/018780 2009/07 12.02.2009 (30) 08.08.2007 CN 200710029644 (54) ANDROGRAPHOLIDDERIVATE UND DE- REN VERWENDUNG BEI DER HERSTEL- LUNG VON MEDIKAMENTEN ANDROGRAPHOLIDE DERIVATIVES AND USE THEREOF IN MANUFACTURE OF MEDICAMENTS DÉRIVÉS D'ANDROGRAPHOLIDE ET LEUR UTILISATION POUR LA FABRICA- TION DE MÉDICAMENTS (73) Panorama Research Inc., 1230 Bordeaux Drive, Sunnyvale, CA 94089, US (72) WANG, Yuqiang, Guangdong 510632, CN JIANG, Xiaojian, Guangdong 510632, CN JIANG, Jie, Guangdong 510632, CN ZHANG, Zaijun, Guangdong 510632, CN YANG, Zhaoqi, Guangdong 510632, CN YU, Pei, Guangdong 510632, CN (74) UEXKÜLL & STOLBERG, Patentanwälte Beselerstrasse 4, 22607 Hamburg, DE C07D 409/12 → (51) C07D 211/58

(C07D) II.1(1) C07D 409/12 → (51) C07D 213/75 C07D 409/14 → (51) C07D 213/75 (51) C07D 413/04 (11) 1 951 718 B1 C07D 413/14 A61K 31/454 A61P 25/00 (25) En (26) En (21) 06829087.3 (22) 21.11.2006 (84) AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR AL BA HR MK RS (43) 06.08.2008 (86) EP 2006/011150 21.11.2006 (87) WO 2007/057229 2007/21 24.05.2007 (30) 21.11.2005 US 739107 P (54) 4-OXADIAZOLYLPIPERIDINVERBINDUN- GEN UND DEREN VERWENDUNG 4-OXADIAZOLYL-PIPERIDINE COMPOUNDS AND USE THEREOF COMPOSES A BASE DE 4-OXADIAZOLYL- PIPERIDINE ET UTILISATION DE CEUX-CI (73) Purdue Pharma LP, One Stamford Forum 201 Tresser Boulevard, Stamford, CT 06901, US (72) TAFESSE, Laykea, Robbinsville, NJ 08691, US (74) Maiwald, Walter, Maiwald Patentanwalts GmbH Elisenhof Elisenstrasse 3, 80335 München, DE (60) 10010919.8 / 2 298 764 10010920.6 / 2 298 765 C07D 413/06 → (51) C07D 213/75 C07D 413/12 → (51) A01N 43/40 C07D 413/12 → (51) C07D 213/75 (51) C07D 413/14 (11) 2 203 447 B1 A61K 31/538 A61P 35/00 (25) En (26) En (21) 08804483.9 (22) 19.09.2008 (84) AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR AL BA MK RS (43) 07.07.2010 (86) EP 2008/062551 19.09.2008 (87) WO 2009/037343 2009/13 26.03.2009 (30) 21.09.2007 EP 07116897 21.09.2007 US 974240 P (54) INHIBITOREN DER WECHSELWIRKUNG ZWISCHEN MDM2 UND P53 INHIBITORS OF THE INTERACTION BETWEEN MDM2 AND P53 INHIBITEURS DE L'INTERACTION ENTRE MDM2 ET P53 (73) Janssen Pharmaceutica, N.V., Turnhoutseweg 30, 2340 Beerse, BE (72) STORCK, Pierre-Henri, Ramsgate Kent CT11 8BB, GB SCHOENTJES, Bruno, F-27106 Val De Reuil Cedex, FR PIETTRE, Arnaud Marcel Pierre, CH-4123 Allschwil, CH ERMERT, Philipp, CH-4123 Allschwil, CH PONCELET, Virginie Sophie, F-27106 Val De Reuil Cedex, FR CSOKA, Imre Christian Francis, F-27106 Val De Reuil Cedex, FR (74) Vervoort, Liesbeth, Janssen Pharmaceutica N.V. Turnhoutseweg 30, 2340 Beerse, BE C07D 413/14 → (51) C07D 413/04 Europäisches Patentblatt European Patent Bulletin Bulletin européen des brevets (51) C07D 417/04 (11) 1 542 997 B1 A61P 35/00 A61K 31/428 (25) En (26) En (21) 03771002.7 (22) 23.07.2003 (84) AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR (43) 22.06.2005 (86) CA 2003/001078 23.07.2003 (87) WO 2004/011460 2004/06 05.02.2004 (30) 24.07.2002 US 398504 P (54) PYRAZOLYLBENZOTHIAZOLDERIVATE UND DEREN VERWENDUNG ALS THERA- PEUTISCHE MITTEL PYRAZOLYLBENZOTHIAZOLE DERI- VATIVES AND THEIR USE AS THERA- PEUTIC AGENTS DERIVES DE PYRAZOLYLBENZOTHIA- ZOLE ET LEUR UTILISATION EN TANT QU' AGENTS THERAPEUTIQUES (73) Dermira (Canada), Inc., 777 Dunsmuir Street, Suite 1300, Vancouver, BC V7Y 1K2, CA (72) ZHANG, Zaihui, Vancouver, British Columbia V6L 2N9, CA DAYNARD, Timothy, S., Vancouver, British Columbia V6P 2G4, CA WANG, Shisen, Coquitlam, British Columbia V3E 2M1, CA DU, Xinyao, Richmond, British Colombia V6V 2A4, CA CHOPIUK, Gregory, B., San Diego, CA 92130, US YAN, Jun, Coquitlam, British Columbia V3K 1V3, CA CHEN, Jianxin, Vancouver, British Columbia V6S 1B7, CA SVIRIDOV, Serguei, V., Burnaby, British Columbia V5H 4N8, CA (74) Crooks, Elizabeth Caroline, et al, Kilburn & Strode LLP 20 Red Lion Street, London WC1R 4PJ, GB (51) C07D 417/04 (11) 2 039 686 B1 A61K 31/506 A61P 31/12 A61P 1/16 (25) Zh (26) En (21) 07764006.8 (22) 09.07.2007 (84) AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR (43) 25.03.2009 (86) CN 2007/002098 09.07.2007 (87) WO 2008/009209 2008/04 24.01.2008 (30) 10.07.2006 CN 200610098646 (54) DIHYDROPYRIMIDINVERBINDUNGEN UND IHRE VERWENDUNGEN BEI DER HERSTELLUNG VON MEDIKAMENTEN ZUR BEHANDLUNG UND PRÄVENTION ANTIVIRALER KRANKHEITEN DIHYDROPYRIMIDINE COMPOUNDS AND THEIR USES IN PREPARATION OF MEDI- CAMENTS FOR TREATING AND PREVENTING ANTIVIRAL DISEASES COMPOSÉS DE DIHYDROPYRIMIDINE ET LEURS UTILISATIONS DANS LA PRÉPA- RATION DE MÉDICAMENTS POUR TRAITER ET PRÉVENIR DES MALADIES ANTIVIRALES (73) Beijing Molecule Science and Technology Co., Ltd., Apt. 301, Attached Building of Zizhu Building No. 44, Hongliannancun Haidian District, Beijing 100088, CN (72) LI, Song, Beijing 100850, CN ZHAO, Guoming, Beijing 100850, CN XIA, Guangqiang, Beijing 100850, CN WANG, Lili, Beijing 100850, CN ZHENG, Zhibing, Beijing 100850, CN XIE, Yunde, Beijing 100850, CN ZHONG, Wu, Beijing 100850, CN 659 Patente Patents Brevets (09/2012) 29.02.2012 XIAO, Junhai, Beijing 100850, CN LI, Xingzhou, Beijing 100850, CN CUI, Hao, Beijing 100850, CN (74) Mammel und Maser, Patentanwälte Tilsiter Straße 3, 71065 Sindelfingen, DE (60) 11000422.3 / 2 336 115 C07D 417/06 → (51) C07D 213/75 C07D 417/12 → (51) A01N 43/40 C07D 417/12 → (51) C07D 403/12 C07D 417/14 → (51) A01N 43/40 C07D 471/04 → (51) C07D 213/75 C07D 471/04 → (51) C07D 487/04 (51) C07D 471/14 (11) 2 036 907 B1 C07F 15/00 H01L 51/00 C09K 11/87 H05B 33/14 (25) En (26) En (21) 08016208.4 (22) 15.09.2008 (84) AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR (43) 18.03.2009 (30) 14.09.2007 JP 2007239652 20.12.2007 JP 2007329145 28.07.2008 JP 2008194095 (54) Organische Elektrolumineszenzvorrichtung Organic electroluminescence device Dispositif électroluminescent organique (73) FUJIFILM Corporation, 26-30, Nishiazabu 2chome, Minato-ku Tokyo, JP (72) Murakami, Takeshi, Ashigarakmi-gun, Kanagawa, JP Kinoshita, Ikuo, Ashigarakmi-gun, Kanagawa, JP Yagi, Kazunari, Ashigarakmi-gun, Kanagawa, JP Takada, Saki, Ashigarakmi-gun, Kanagawa, JP Takeda, Akira, Ashigarakmi-gun, Kanagawa, JP Sotoyama, Wataru, Ashigarakmi-gun, Kanagawa, JP Takizawa, Hiroo, Ashigarakmi-gun, Kanagawa, JP (74) HOFFMANN EITLE, Patent- und Rechtsanwälte Arabellastraße 4, 81925 München, DE (51) C07D 473/32 (11) 2 184 286 B1 (25) En (26) En (21) 08019325.3 (22) 05.11.2008 (84) AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR (43) 12.05.2010 (54) Verfahren zur Herstellung von Acyclovir- Prodrugs Process for the manufacture of acyclovir pro-drugs Procédé de fabrication de pro-médicaments acyclovir (73) Cognis IP Management GmbH, Henkelstr. 67, 40589 Düsseldorf, DE Universidad Complutense De Madrid, Plaza. Ramon y Cajal s/n, 28040 Madrid, ES (72) Bigorra Llosas, Joaquin, 08201 Sabadell, ES Valls, Ramon, 08022 Barcelona, ES Raya, Javier, 08970 Sant Joan Despí, ES Fabry, Bernd, 41352 Korschenbroich, DE De Regil-Hernandez, Ruben, 28017 Madrid, ES Rodriguez-Bayon, Amalia, 28034 Madrid, ES

(C07D) II.1(1)<br />

C07D 4<strong>09</strong>/12 → (51) C07D 213/75<br />

C07D 4<strong>09</strong>/14 → (51) C07D 213/75<br />

(51) C07D 413/04 (11) 1 951 718 B1<br />

C07D 413/14 A61K 31/454<br />

A61P 25/00<br />

(25) En (26) En<br />

(21) 06829087.3 (22) 21.11.2006<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HU IE IS IT LI LT LU LV MC NL PL PT<br />

RO SE SI SK TR<br />

AL BA HR MK RS<br />

(43) 06.08.2008<br />

(86) EP 2006/011150 21.11.2006<br />

(87) WO 2007/057229 2007/21 24.05.2007<br />

(30) 21.11.2005 US 739107 P<br />

(54) 4-OXADIAZOLYLPIPERIDINVERBINDUN-<br />

GEN UND DEREN VERWENDUNG<br />

4-OXADIAZOLYL-PIPERIDINE<br />

COMPOUNDS AND USE THEREOF<br />

COMPOSES A BASE DE 4-OXADIAZOLYL-<br />

PIPERIDINE ET UTILISATION DE CEUX-CI<br />

(73) Purdue Pharma LP, One Stamford Forum<br />

201 Tresser Boulevard, Stamford, CT 06901,<br />

US<br />

(72) TAFESSE, Laykea, Robbinsville, NJ 08691,<br />

US<br />

(74) Maiwald, Walter, Maiwald <strong>Patent</strong>anwalts<br />

GmbH Elisenhof Elisenstrasse 3, 80335<br />

München, DE<br />

(60) 1001<strong>09</strong>19.8 / 2 298 764<br />

1001<strong>09</strong>20.6 / 2 298 765<br />

C07D 413/06 → (51) C07D 213/75<br />

C07D 413/12 → (51) A01N 43/40<br />

C07D 413/12 → (51) C07D 213/75<br />

(51) C07D 413/14 (11) 2 203 447 B1<br />

A61K 31/538 A61P 35/00<br />

(25) En (26) En<br />

(21) 08804483.9 (22) 19.<strong>09</strong>.2008<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HR HU IE IS IT LI LT LU LV MC MT NL<br />

NO PL PT RO SE SI SK TR<br />

AL BA MK RS<br />

(43) 07.07.2010<br />

(86) EP 2008/062551 19.<strong>09</strong>.2008<br />

(87) WO 20<strong>09</strong>/037343 20<strong>09</strong>/13 26.03.20<strong>09</strong><br />

(30) 21.<strong>09</strong>.2007 EP 07116897<br />

21.<strong>09</strong>.2007 US 974240 P<br />

(54) INHIBITOREN DER WECHSELWIRKUNG<br />

ZWISCHEN MDM2 UND P53<br />

INHIBITORS OF THE INTERACTION<br />

BETWEEN MDM2 AND P53<br />

INHIBITEURS DE L'INTERACTION ENTRE<br />

MDM2 ET P53<br />

(73) Janssen Pharmaceutica, N.V., Turnhoutseweg<br />

30, 2340 Beerse, BE<br />

(72) STORCK, Pierre-Henri, Ramsgate Kent CT11<br />

8BB, GB<br />

SCHOENTJES, Bruno, F-27106 Val De Reuil<br />

Cedex, FR<br />

PIETTRE, Arnaud Marcel Pierre, CH-4123<br />

Allschwil, CH<br />

ERMERT, Philipp, CH-4123 Allschwil, CH<br />

PONCELET, Virginie Sophie, F-27106 Val De<br />

Reuil Cedex, FR<br />

CSOKA, Imre Christian Francis, F-27106 Val<br />

De Reuil Cedex, FR<br />

(74) Vervoort, Liesbeth, Janssen Pharmaceutica<br />

N.V. Turnhoutseweg 30, 2340 Beerse, BE<br />

C07D 413/14 → (51) C07D 413/04<br />

Europäisches <strong>Patent</strong>blatt<br />

<strong>European</strong> <strong>Patent</strong> <strong>Bulletin</strong><br />

<strong>Bulletin</strong> européen des brevets<br />

(51) C07D 417/04 (11) 1 542 997 B1<br />

A61P 35/00 A61K 31/428<br />

(25) En (26) En<br />

(21) 03771002.7 (22) 23.07.2003<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HU IE IT LI LU MC NL PT RO SE SI SK<br />

TR<br />

(43) 22.06.2005<br />

(86) CA 2003/001078 23.07.2003<br />

(87) WO 2004/011460 2004/06 05.02.2004<br />

(30) 24.07.2002 US 398504 P<br />

(54) PYRAZOLYLBENZOTHIAZOLDERIVATE<br />

UND DEREN VERWENDUNG ALS THERA-<br />

PEUTISCHE MITTEL<br />

PYRAZOLYLBENZOTHIAZOLE DERI-<br />

VATIVES AND THEIR USE AS THERA-<br />

PEUTIC AGENTS<br />

DERIVES DE PYRAZOLYLBENZOTHIA-<br />

ZOLE ET LEUR UTILISATION EN TANT<br />

QU' AGENTS THERAPEUTIQUES<br />

(73) Dermira (Canada), Inc., 777 Dunsmuir<br />

Street, Suite 1300, Vancouver, BC V7Y 1K2,<br />

CA<br />

(72) ZHANG, Zaihui, Vancouver, British Columbia<br />

V6L 2N9, CA<br />

DAYNARD, Timothy, S., Vancouver, British<br />

Columbia V6P 2G4, CA<br />

WANG, Shisen, Coquitlam, British Columbia<br />

V3E 2M1, CA<br />

DU, Xinyao, Richmond, British Colombia<br />

V6V 2A4, CA<br />

CHOPIUK, Gregory, B., San Diego, CA<br />

92130, US<br />

YAN, Jun, Coquitlam, British Columbia V3K<br />

1V3, CA<br />

CHEN, Jianxin, Vancouver, British Columbia<br />

V6S 1B7, CA<br />

SVIRIDOV, Serguei, V., Burnaby, British<br />

Columbia V5H 4N8, CA<br />

(74) Crooks, Elizabeth Caroline, et al, Kilburn &<br />

Strode LLP 20 Red Lion Street, London<br />

WC1R 4PJ, GB<br />

(51) C07D 417/04 (11) 2 039 686 B1<br />

A61K 31/506 A61P 31/12<br />

A61P 1/16<br />

(25) Zh (26) En<br />

(21) 07764006.8 (22) <strong>09</strong>.07.2007<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HU IE IS IT LI LT LU LV MC MT NL PL<br />

PT RO SE SI SK TR<br />

(43) 25.03.20<strong>09</strong><br />

(86) CN 2007/002<strong>09</strong>8 <strong>09</strong>.07.2007<br />

(87) WO 2008/0<strong>09</strong>2<strong>09</strong> 2008/04 24.01.2008<br />

(30) 10.07.2006 CN 200610<strong>09</strong>8646<br />

(54) DIHYDROPYRIMIDINVERBINDUNGEN<br />

UND IHRE VERWENDUNGEN BEI DER<br />

HERSTELLUNG VON MEDIKAMENTEN<br />

ZUR BEHANDLUNG UND PRÄVENTION<br />

ANTIVIRALER KRANKHEITEN<br />

DIHYDROPYRIMIDINE COMPOUNDS AND<br />

THEIR USES IN PREPARATION OF MEDI-<br />

CAMENTS FOR TREATING AND<br />

PREVENTING ANTIVIRAL DISEASES<br />

COMPOSÉS DE DIHYDROPYRIMIDINE ET<br />

LEURS UTILISATIONS DANS LA PRÉPA-<br />

RATION DE MÉDICAMENTS POUR<br />

TRAITER ET PRÉVENIR DES MALADIES<br />

ANTIVIRALES<br />

(73) Beijing Molecule Science and Technology<br />

Co., Ltd., Apt. 301, Attached Building of<br />

Zizhu Building No. 44, Hongliannancun<br />

Haidian District, Beijing 100088, CN<br />

(72) LI, Song, Beijing 100850, CN<br />

ZHAO, Guoming, Beijing 100850, CN<br />

XIA, Guangqiang, Beijing 100850, CN<br />

WANG, Lili, Beijing 100850, CN<br />

ZHENG, Zhibing, Beijing 100850, CN<br />

XIE, Yunde, Beijing 100850, CN<br />

ZHONG, Wu, Beijing 100850, CN<br />

659<br />

<strong>Patent</strong>e<br />

<strong>Patent</strong>s<br />

Brevets (<strong>09</strong>/<strong>2012</strong>) 29.02.<strong>2012</strong><br />

XIAO, Junhai, Beijing 100850, CN<br />

LI, Xingzhou, Beijing 100850, CN<br />

CUI, Hao, Beijing 100850, CN<br />

(74) Mammel und Maser, <strong>Patent</strong>anwälte Tilsiter<br />

Straße 3, 71065 Sindelfingen, DE<br />

(60) 11000422.3 / 2 336 115<br />

C07D 417/06 → (51) C07D 213/75<br />

C07D 417/12 → (51) A01N 43/40<br />

C07D 417/12 → (51) C07D 403/12<br />

C07D 417/14 → (51) A01N 43/40<br />

C07D 471/04 → (51) C07D 213/75<br />

C07D 471/04 → (51) C07D 487/04<br />

(51) C07D 471/14 (11) 2 036 907 B1<br />

C07F 15/00 H01L 51/00<br />

C<strong>09</strong>K 11/87 H05B 33/14<br />

(25) En (26) En<br />

(21) 08016208.4 (22) 15.<strong>09</strong>.2008<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HR HU IE IS IT LI LT LU LV MC MT NL<br />

NO PL PT RO SE SI SK TR<br />

(43) 18.03.20<strong>09</strong><br />

(30) 14.<strong>09</strong>.2007 JP 2007239652<br />

20.12.2007 JP 2007329145<br />

28.07.2008 JP 2008194<strong>09</strong>5<br />

(54) Organische Elektrolumineszenzvorrichtung<br />

Organic electroluminescence device<br />

Dispositif électroluminescent organique<br />

(73) FUJIFILM Corporation, 26-30, Nishiazabu 2chome,<br />

Minato-ku Tokyo, JP<br />

(72) Murakami, Takeshi, Ashigarakmi-gun,<br />

Kanagawa, JP<br />

Kinoshita, Ikuo, Ashigarakmi-gun,<br />

Kanagawa, JP<br />

Yagi, Kazunari, Ashigarakmi-gun, Kanagawa,<br />

JP<br />

Takada, Saki, Ashigarakmi-gun, Kanagawa,<br />

JP<br />

Takeda, Akira, Ashigarakmi-gun, Kanagawa,<br />

JP<br />

Sotoyama, Wataru, Ashigarakmi-gun,<br />

Kanagawa, JP<br />

Takizawa, Hiroo, Ashigarakmi-gun,<br />

Kanagawa, JP<br />

(74) HOFFMANN EITLE, <strong>Patent</strong>- und Rechtsanwälte<br />

Arabellastraße 4, 81925 München,<br />

DE<br />

(51) C07D 473/32 (11) 2 184 286 B1<br />

(25) En (26) En<br />

(21) 08019325.3 (22) 05.11.2008<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HR HU IE IS IT LI LT LU LV MC MT NL<br />

NO PL PT RO SE SI SK TR<br />

(43) 12.05.2010<br />

(54) Verfahren zur Herstellung von Acyclovir-<br />

Prodrugs<br />

Process for the manufacture of acyclovir<br />

pro-drugs<br />

Procédé de fabrication de pro-médicaments<br />

acyclovir<br />

(73) Cognis IP Management GmbH, Henkelstr.<br />

67, 40589 Düsseldorf, DE<br />

Universidad Complutense De Madrid, Plaza.<br />

Ramon y Cajal s/n, 28040 Madrid, ES<br />

(72) Bigorra Llosas, Joaquin, 08201 Sabadell, ES<br />

Valls, Ramon, 08022 Barcelona, ES<br />

Raya, Javier, 08970 Sant Joan Despí, ES<br />

Fabry, Bernd, 41352 Korschenbroich, DE<br />

De Regil-Hernandez, Ruben, 28017 Madrid,<br />

ES<br />

Rodriguez-Bayon, Amalia, 28034 Madrid, ES

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