European Patent Bulletin 2012/09 - European Patent Office
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European Patent Bulletin 2012/09 - European Patent Office

European Patent Bulletin 2012/09 - European Patent Office European Patent Bulletin 2012/09 - European Patent Office

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(A61K) I.1(2) (84) AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR AL BA HR MK RS (30) 06.07.2006 EP 06014002 (54) Pharmazeutische Zusammensetzung enthaltend eine Tetrahydrofolsäure Pharmaceutical composition containing a tetrahydrofolic acid Composition pharmaceutique contenant un acide tetrahydrofolique (71) Bayer Pharma Aktiengesellschaft, Müllerstrasse 178, 13353 Berlin, DE (72) King, Christina, 10437 Berlin, DE (74) Plougmann & Vingtoft A/S, Sundkrogsgade 9 P.O. Box 831, 2100 Copenhagen Ø, DK (62) 07764936.6 / 2 040 683 A61K 9/20 → (51) A61K 31/496 A61K 9/20 → (51) C07D 495/04 A61K 9/48 → (51) C07D 495/04 (51) A61K 9/50 (11) 2 422 775 A2 (25) En (26) En (21) 11005556.3 (22) 22.09.2003 (84) AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR (30) 20.09.2002 US 412208 P (27) 22.09.2003 PCT/US03/29475 (54) Sequestriermitteluntereinheit und zugehörige Zusammensetzungen und Verfahren Sequestering subunit and related compositions and methods Séquestration de sous-unité et compositions et procédés associés (71) Alpharma, Inc., One Executive Drive, Fort Lee, NJ 07024, US (72) Boehm, Garth, Westfield, NJ 07090, US (74) Pfenning, Meinig & Partner GbR, Patentund Rechtsanwälte Theresienhöhe 13, 80339 München, DE (62) 03752490.7 / 1 551 372 A61K 9/50 → (51) A61K 9/20 (51) A61K 9/51 (11) 2 422 776 A1 A61K 31/337 A61P 35/00 (25) Es (26) En (21) 10766686.9 (22) 22.04.2010 (84) AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR (86) ES 2010/070247 22.04.2010 (87) WO 2010/122204 2010/43 28.10.2010 (30) 22.04.2009 ES 200901098 (54) POLYARGININNANOKAPSELN POLYARGININE NANOCAPSULES NANOCAPSULES DE POLYARGININE (71) Universidade De Santiago De Compostela, Edificio CACTUS - Campus sur, 15782 Santiago de Compostela, ES (72) LOZANO LOPEZ, Victoria, , ES ALONSO FERNANDEZ, Maria Jose, , ES TORRES LOPEZ, Dolores, , ES (74) ABG Patentes, S.L., Avenida de Burgos 16D Edificio Euromor, 28036 Madrid, ES A61K 31/00 → (51) C07K 16/28 (51) A61K 31/05 (11) 2 422 777 A1 A61K 31/198 A61K 31/53 (25) De (26) De (21) 10173500.9 (22) 20.08.2010 Europäisches Patentblatt European Patent Bulletin Bulletin européen des brevets (84) AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR BA ME RS (54) Synergistische Wirkung von Modulatoren des NO-Stoffwechsels und der NADPH- Oxidase bei der Sensitivierung von Tumorzellen Synergistic effect of modulators for NO metabolism and NADPH oxidase during sensitization of tumour cells Effet synergétique de modulateurs du changement de matière NO et de la NADPH-oxydase dans la sensibilisation de cellules tumorales (71) Universitätsklinikum Freiburg, Hugstetter Strasse 49, 79106 Freiburg, DE (72) Bauer, Georg, 79104, Freiburg, DE (74) Keller, Günter, et al, Lederer & Keller Patentanwälte Unsöldstrasse 2, 80538 München, DE A61K 31/05 → (51) A61K 31/5513 A61K 31/10 → (51) C07C 45/71 A61K 31/121 → (51) C07C 45/71 (51) A61K 31/137 (11) 2 422 778 A1 A61P 25/04 (25) En (26) En (21) 11008908.3 (22) 21.04.2008 (84) AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT RO SE SI SK TR (30) 23.04.2007 EP 07008218 (54) Titration von Tapentadol Titration of tapentadol Titration du tapentadol (71) Grünenthal GmbH, Zieglerstrasse 6, 52078 Aachen, DE (72) Lange, Claudia, 40239 Düsseldorf, DE Rombout, Ferdinand, Klimmen 6343 CL, NL (74) Bülle, Jan, et al, Patentanwälte Kutzenberger & Wolff Theodor-Heuss-Ring 23, 50668 Köln, DE (62) 08749016.5 / 2 148 670 A61K 31/137 → (51) A61K 9/127 A61K 31/15 → (51) C07C 45/71 A61K 31/167 → (51) A61K 9/12 A61K 31/19 → (51) C09K 3/00 (51) A61K 31/192 (11) 2 422 779 A1 A61K 31/437 A61K 31/4412 A61P 35/00 A61P 43/00 C07D 213/64 C07D 471/04 (25) Ja (26) En (21) 10767106.7 (22) 22.04.2010 (84) AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR (86) JP 2010/057114 22.04.2010 (87) WO 2010/123049 2010/43 28.10.2010 (30) 22.04.2009 JP 2009104568 27.01.2010 JP 2010015445 (54) SELEKTIVE EP4-REZEPTORAGONISTEN- SUBSTANZ ZUR KREBSBEHANDLUNG SELECTIVE EP4 RECEPTOR AGONISTIC SUBSTANCE FOR TREATMENT OF CANCER SUBSTANCE AGONISTE SÉLECTIVE DU RÉCEPTEUR EP4 POUR LE TRAITEMENT DU CANCER (71) RaQualia Pharma Inc, 2, Aza 5-gochi Taketoyo-cho, Chita-gun Aichi-ken 470 2341, JP 202 Anmeldungen Applications Demandes (09/2012) 29.02.2012 (72) TAKE, Yukinori, Chita-gun Aichi 470-2341, JP KOIZUMI, Shinichi, Chita-gun Aichi 470- 2341, JP OKUMURA, Takako, Chita-gun Aichi 470- 2341, JP NONOMURA, Kazuhiko, Chita-gun Aichi 470- 2341, JP (74) Teipel, Stephan, et al, Lederer & Keller Patentanwälte Unsöldstrasse 2, 80538 München, DE A61K 31/196 → (51) A61K 9/12 A61K 31/198 → (51) A61K 31/05 A61K 31/205 → (51) A61K 31/575 A61K 31/216 → (51) A61K 31/513 (51) A61K 31/335 (11) 2 422 780 A1 C07D 231/56 C07D 311/74 A61K 31/416 A61K 31/343 A61K 31/353 A61K 31/665 C07D 493/04 A61P 31/18 (25) En (26) En (21) 11188134.8 (22) 09.05.2005 (84) AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR (30) 07.05.2004 US 568935 P (54) Resistenzabweisende retrovirale Proteaseinhibitoren Resistance-repellent retroviral protease inhibitors Inhibiteurs de la protéase rétrovirale résistants/répulsifs (71) Sequoia Pharmaceuticals, Inc., 401 Professional Drive, Suite 100, Gaithersburg, MD 20879, US (72) Eissenstat, Michael, Frederick, MD Maryland 21702, US Delahanty, Greg, Silver Spring, MD Maryland 20901, US Topin, Andrey, Highland, MD Maryland 20777, US Rajendran, Gnana Ravi, Gaithersburg, MD Maryland 20877, US (74) Carpmaels & Ransford, One Southampton Row, London WC1B 5HA, GB (62) 05745707.9 / 1 750 696 (51) A61K 31/335 (11) 2 422 781 A1 C07D 231/56 C07D 311/74 A61K 31/416 A61K 31/343 A61K 31/353 A61K 31/665 C07D 493/04 A61P 31/18 (25) En (26) En (21) 11188135.5 (22) 09.05.2005 (84) AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR (30) 07.05.2004 US 568935 P (54) Resistenzabweisende retrovirale Proteaseinhibitoren Resistance-repellent retroviral protease inhibitors Inhibiteurs de la protéase rétrovirale résistants/répulsifs (71) Sequoia Pharmaceuticals, Inc., 401 Professional Drive, Suite 100, Gaithersburg, MD 20879, US (72) Eissenstat, Michael, Frederick, MD Maryland 21702, US Delahanty, Greg, Silver Spring, MD Maryland 20901, US Topin, Andrey, Highland, MD Maryland 20777, US Rajendran, Gnana Ravi, Gaithersburg, MD Maryland 20877, US

(A61K) I.1(2) (74) Carpmaels & Ransford, One Southampton Row, London WC1B 5HA, GB (62) 05745707.9 / 1 750 696 A61K 31/337 → (51) A61K 9/51 A61K 31/343 → (51) A61K 31/335 A61K 31/343 → (51) C07C 235/46 A61K 31/351 → (51) C07C 235/46 A61K 31/352 → (51) A61P 35/00 A61K 31/353 → (51) A61K 31/335 A61K 31/353 → (51) A61K 31/513 A61K 31/353 → (51) A61K 45/06 A61K 31/353 → (51) A61P 35/00 A61K 31/357 → (51) C07C 235/46 A61K 31/36 → (51) C07C 235/46 A61K 31/381 → (51) C07C 235/46 A61K 31/382 → (51) C07D 495/04 A61K 31/40 → (51) A61K 9/00 A61K 31/40 → (51) C07C 43/225 A61K 31/40 → (51) C07C 235/46 A61K 31/4015 → (51) C07C 43/225 A61K 31/402 → (51) C07C 235/46 A61K 31/4025 → (51) C12P 17/16 A61K 31/403 → (51) C07D 209/14 A61K 31/4035 → (51) C07C 235/46 A61K 31/404 → (51) A61P 35/00 A61K 31/404 → (51) C07C 235/46 A61K 31/405 → (51) C07D 209/14 A61K 31/41 → (51) C07C 235/46 A61K 31/415 → (51) C07C 235/46 A61K 31/416 → (51) A61K 31/335 A61K 31/421 → (51) C07C 235/46 A61K 31/427 → (51) C07D 277/20 A61K 31/4365 → (51) C07D 495/04 A61K 31/437 → (51) A61K 31/192 (51) A61K 31/44 (11) 2 422 782 A1 (25) En (26) En (21) 11168901.4 (22) 11.04.2005 (84) AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR AL BA HR LV MK YU (30) 09.04.2004 US 560894 08.04.2005 US 102559 (54) Verfahren zur Verwendung von Aminopyrin-Zusammensetzungen mit verzögerter Freisetzung Europäisches Patentblatt European Patent Bulletin Bulletin européen des brevets Methods of Using Sustained Release Aminopyridine Compositions Utilisation de compositions d'aminopyridine à libération soutenue (71) Acorda Therapeutics, Inc., 15 Skyline Drive, Hawthorne NY 10531, US (72) Blight, Andrew R., Mahopac, NY 10541, US Cohen, Ron, Irvington, NY 10533, US (74) Carpmaels & Ransford, One Southampton Row, London WC1B 5HA, GB (62) 05732613.4 / 1 732 548 A61K 31/44 → (51) A61K 31/513 A61K 31/44 → (51) C07D 213/65 A61K 31/4406 → (51) A61K 45/00 A61K 31/4412 → (51) A61K 31/192 A61K 31/4418 → (51) C07D 213/65 A61K 31/443 → (51) C07D 213/65 A61K 31/4433 → (51) C07D 213/65 A61K 31/4439 → (51) C07D 213/65 A61K 31/454 → (51) C07D 209/14 A61K 31/454 → (51) C07D 277/20 A61K 31/4709 → (51) C07D 277/20 A61K 31/4709 → (51) C07D 401/12 A61K 31/472 → (51) C07D 217/22 A61K 31/4725 → (51) C07D 217/22 (51) A61K 31/496 (11) 2 422 783 A1 A61K 9/20 A61K 47/10 A61K 47/26 A61K 47/38 C07D 417/12 (25) En (26) En (21) 11181100.6 (22) 26.05.2006 (84) AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR (30) 26.05.2005 JP 2005153508 (54) Pharmazeutische Zusammensetzung Pharmaceutical Composition Composition pharmaceutique (71) Dainippon Sumitomo Pharma Co., Ltd., 6-8, Dosho-machi 2-chome Chuo-ku Osaka-shi, Osaka 541-8524, JP (72) Fujihara, Kazuyuki, Ibaraki-shi, Osaka 567- 0878, JP (74) Vossius & Partner, Siebertstrasse 4, 81675 München, DE (62) 06746900.7 / 1 884 242 A61K 31/496 → (51) A61K 9/12 A61K 31/496 → (51) C07D 277/20 (51) A61K 31/513 (11) 2 422 784 A1 A61K 31/216 A61P 35/00 A61K 31/353 (25) En (26) En (21) 10173256.8 (22) 18.08.2010 (84) AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR BA ME RS (54) Zusammensetzung aus TEGAFUR und Kaffeinsäurephenethyl-Ester (CAPE) und entweder Catechin, Kaempherol, Myrecetin oder Luteolin zur Potenzierung der 203 Anmeldungen Applications Demandes (09/2012) 29.02.2012 Antitumor-Wirkung und zur Behandlung von Tumoren Composition of TEGAFUR, caffeic acid phenethyl ester (CAPE) and either catechin, kaempherol, myricetin or luteolin for potentiating antitumour effect and for treating tumours Composition de TEGAFUR et d'ester phénéthylique de l'acide caféique (CAPE) en combinaison avec de catéchine, de caempherol, de myricetine ou de luteoline pour augmenter l'effet anti-tumeur et pour traiter des tumeurs (71) Grindeks, a joint stock company, 53, Krustpils Street, 1057 Riga, LV (72) Kalvins, Ivars, 1006 Riga, LV Stonans, Ilmars, 1057 Riga, LV Sestakova, Irina, 1006 Riga, LV Domracova, Ilona, 1006 Riga, LV Jascenko, Elina, 1006 Riga, LV Bridane, Veronika, 1006 Riga, LV Kanepe, Iveta, 1006 Riga, LV (51) A61K 31/513 (11) 2 422 785 A1 A61K 31/44 A61P 35/00 A61P 43/00 C07D 405/02 (25) Ja (26) En (21) 10767135.6 (22) 22.04.2010 (84) AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK SM TR (86) JP 2010/057176 22.04.2010 (87) WO 2010/123078 2010/43 28.10.2010 (30) 22.04.2009 JP 2009104189 (54) VERFAHREN ZUR VORHERSAGE DER WIRKSAMKEIT VON CHEMOTHERAPIE BEI NIERENZELLKARZINOM METHOD FOR PREDICTING THERA- PEUTIC EFFECT OF CHEMOTHERAPY ON RENAL CELL CANCER PROCÉDÉ DE PRÉDICTION DE L'EFFET THÉRAPEUTIQUE D'UNE CHIMIOTHÉ- RAPIE SUR UN CANCER À CELLULES RÉNALES (71) Taiho Pharmaceutical Co., Ltd., 1-27, Kandanishiki-cho, Chiyoda-ku, Tokyo 101- 8444, JP (72) AKAZA, Hideyuki, Tokyo 160-0023, JP NAITO, Seiji, Fukuoka-shi Fukuoka 810- 0053, JP OKA, Toshinori, Tokushima-shi Tokushima 771-0194, JP (74) Vossius & Partner, Siebertstrasse 4, 81675 München, DE A61K 31/513 → (51) A61K 45/06 A61K 31/513 → (51) A61P 35/00 A61K 31/513 → (51) C07D 401/04 A61K 31/525 → (51) A61K 9/20 A61K 31/53 → (51) A61K 31/05 A61K 31/536 → (51) C07D 265/26 A61K 31/5377 → (51) C07D 277/20 A61K 31/5377 → (51) C07D 401/04 (51) A61K 31/538 (11) 2 422 786 A1 A61P 11/06 (25) De (26) De (21) 11187038.2 (22) 18.04.2005 (84) AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR (30) 07.02.2005 EP 05002496 22.04.2004 DE 102004019540

(A61K) I.1(2)<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HU IE IS IT LI LT LU LV MC MT NL PL<br />

PT RO SE SI SK TR<br />

AL BA HR MK RS<br />

(30) 06.07.2006 EP 06014002<br />

(54) Pharmazeutische Zusammensetzung enthaltend<br />

eine Tetrahydrofolsäure<br />

Pharmaceutical composition containing a<br />

tetrahydrofolic acid<br />

Composition pharmaceutique contenant<br />

un acide tetrahydrofolique<br />

(71) Bayer Pharma Aktiengesellschaft, Müllerstrasse<br />

178, 13353 Berlin, DE<br />

(72) King, Christina, 10437 Berlin, DE<br />

(74) Plougmann & Vingtoft A/S, Sundkrogsgade<br />

9 P.O. Box 831, 2100 Copenhagen Ø, DK<br />

(62) 07764936.6 / 2 040 683<br />

A61K 9/20 → (51) A61K 31/496<br />

A61K 9/20 → (51) C07D 495/04<br />

A61K 9/48 → (51) C07D 495/04<br />

(51) A61K 9/50 (11) 2 422 775 A2<br />

(25) En (26) En<br />

(21) 11005556.3 (22) 22.<strong>09</strong>.2003<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HU IE IT LI LU MC NL PT RO SE SI SK<br />

TR<br />

(30) 20.<strong>09</strong>.2002 US 412208 P<br />

(27) 22.<strong>09</strong>.2003 PCT/US03/29475<br />

(54) Sequestriermitteluntereinheit und zugehörige<br />

Zusammensetzungen und Verfahren<br />

Sequestering subunit and related compositions<br />

and methods<br />

Séquestration de sous-unité et compositions<br />

et procédés associés<br />

(71) Alpharma, Inc., One Executive Drive, Fort<br />

Lee, NJ 07024, US<br />

(72) Boehm, Garth, Westfield, NJ 07<strong>09</strong>0, US<br />

(74) Pfenning, Meinig & Partner GbR, <strong>Patent</strong>und<br />

Rechtsanwälte Theresienhöhe 13,<br />

80339 München, DE<br />

(62) 03752490.7 / 1 551 372<br />

A61K 9/50 → (51) A61K 9/20<br />

(51) A61K 9/51 (11) 2 422 776 A1<br />

A61K 31/337 A61P 35/00<br />

(25) Es (26) En<br />

(21) 10766686.9 (22) 22.04.2010<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HR HU IE IS IT LI LT LU LV MC MK MT<br />

NL NO PL PT RO SE SI SK SM TR<br />

(86) ES 2010/070247 22.04.2010<br />

(87) WO 2010/122204 2010/43 28.10.2010<br />

(30) 22.04.20<strong>09</strong> ES 20<strong>09</strong>01<strong>09</strong>8<br />

(54) POLYARGININNANOKAPSELN<br />

POLYARGININE NANOCAPSULES<br />

NANOCAPSULES DE POLYARGININE<br />

(71) Universidade De Santiago De Compostela,<br />

Edificio CACTUS - Campus sur, 15782 Santiago<br />

de Compostela, ES<br />

(72) LOZANO LOPEZ, Victoria, , ES<br />

ALONSO FERNANDEZ, Maria Jose, , ES<br />

TORRES LOPEZ, Dolores, , ES<br />

(74) ABG <strong>Patent</strong>es, S.L., Avenida de Burgos 16D<br />

Edificio Euromor, 28036 Madrid, ES<br />

A61K 31/00 → (51) C07K 16/28<br />

(51) A61K 31/05 (11) 2 422 777 A1<br />

A61K 31/198 A61K 31/53<br />

(25) De (26) De<br />

(21) 10173500.9 (22) 20.08.2010<br />

Europäisches <strong>Patent</strong>blatt<br />

<strong>European</strong> <strong>Patent</strong> <strong>Bulletin</strong><br />

<strong>Bulletin</strong> européen des brevets<br />

(84) AL AT BE BG CH CY CZ DE DK EE ES FI FR<br />

GB GR HR HU IE IS IT LI LT LU LV MC MK<br />

MT NL NO PL PT RO SE SI SK SM TR<br />

BA ME RS<br />

(54) Synergistische Wirkung von Modulatoren<br />

des NO-Stoffwechsels und der NADPH-<br />

Oxidase bei der Sensitivierung von Tumorzellen<br />

Synergistic effect of modulators for NO<br />

metabolism and NADPH oxidase during<br />

sensitization of tumour cells<br />

Effet synergétique de modulateurs du<br />

changement de matière NO et de la<br />

NADPH-oxydase dans la sensibilisation de<br />

cellules tumorales<br />

(71) Universitätsklinikum Freiburg, Hugstetter<br />

Strasse 49, 79106 Freiburg, DE<br />

(72) Bauer, Georg, 79104, Freiburg, DE<br />

(74) Keller, Günter, et al, Lederer & Keller <strong>Patent</strong>anwälte<br />

Unsöldstrasse 2, 80538 München,<br />

DE<br />

A61K 31/05 → (51) A61K 31/5513<br />

A61K 31/10 → (51) C07C 45/71<br />

A61K 31/121 → (51) C07C 45/71<br />

(51) A61K 31/137 (11) 2 422 778 A1<br />

A61P 25/04<br />

(25) En (26) En<br />

(21) 11008908.3 (22) 21.04.2008<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HR HU IE IS IT LI LT LU LV MC MT NL<br />

NO PL PT RO SE SI SK TR<br />

(30) 23.04.2007 EP 07008218<br />

(54) Titration von Tapentadol<br />

Titration of tapentadol<br />

Titration du tapentadol<br />

(71) Grünenthal GmbH, Zieglerstrasse 6, 52078<br />

Aachen, DE<br />

(72) Lange, Claudia, 40239 Düsseldorf, DE<br />

Rombout, Ferdinand, Klimmen 6343 CL, NL<br />

(74) Bülle, Jan, et al, <strong>Patent</strong>anwälte Kutzenberger<br />

& Wolff Theodor-Heuss-Ring 23, 50668<br />

Köln, DE<br />

(62) 08749016.5 / 2 148 670<br />

A61K 31/137 → (51) A61K 9/127<br />

A61K 31/15 → (51) C07C 45/71<br />

A61K 31/167 → (51) A61K 9/12<br />

A61K 31/19 → (51) C<strong>09</strong>K 3/00<br />

(51) A61K 31/192 (11) 2 422 779 A1<br />

A61K 31/437 A61K 31/4412<br />

A61P 35/00 A61P 43/00<br />

C07D 213/64 C07D 471/04<br />

(25) Ja (26) En<br />

(21) 10767106.7 (22) 22.04.2010<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HR HU IE IS IT LI LT LU LV MC MK MT<br />

NL NO PL PT RO SE SI SK SM TR<br />

(86) JP 2010/057114 22.04.2010<br />

(87) WO 2010/123049 2010/43 28.10.2010<br />

(30) 22.04.20<strong>09</strong> JP 20<strong>09</strong>104568<br />

27.01.2010 JP 2010015445<br />

(54) SELEKTIVE EP4-REZEPTORAGONISTEN-<br />

SUBSTANZ ZUR KREBSBEHANDLUNG<br />

SELECTIVE EP4 RECEPTOR AGONISTIC<br />

SUBSTANCE FOR TREATMENT OF<br />

CANCER<br />

SUBSTANCE AGONISTE SÉLECTIVE DU<br />

RÉCEPTEUR EP4 POUR LE TRAITEMENT<br />

DU CANCER<br />

(71) RaQualia Pharma Inc, 2, Aza 5-gochi<br />

Taketoyo-cho, Chita-gun Aichi-ken 470<br />

2341, JP<br />

202<br />

Anmeldungen<br />

Applications<br />

Demandes (<strong>09</strong>/<strong>2012</strong>) 29.02.<strong>2012</strong><br />

(72) TAKE, Yukinori, Chita-gun Aichi 470-2341,<br />

JP<br />

KOIZUMI, Shinichi, Chita-gun Aichi 470-<br />

2341, JP<br />

OKUMURA, Takako, Chita-gun Aichi 470-<br />

2341, JP<br />

NONOMURA, Kazuhiko, Chita-gun Aichi 470-<br />

2341, JP<br />

(74) Teipel, Stephan, et al, Lederer & Keller <strong>Patent</strong>anwälte<br />

Unsöldstrasse 2, 80538 München,<br />

DE<br />

A61K 31/196 → (51) A61K 9/12<br />

A61K 31/198 → (51) A61K 31/05<br />

A61K 31/205 → (51) A61K 31/575<br />

A61K 31/216 → (51) A61K 31/513<br />

(51) A61K 31/335 (11) 2 422 780 A1<br />

C07D 231/56 C07D 311/74<br />

A61K 31/416 A61K 31/343<br />

A61K 31/353 A61K 31/665<br />

C07D 493/04 A61P 31/18<br />

(25) En (26) En<br />

(21) 11188134.8 (22) <strong>09</strong>.05.2005<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HU IE IS IT LI LT LU MC NL PL PT RO<br />

SE SI SK TR<br />

(30) 07.05.2004 US 568935 P<br />

(54) Resistenzabweisende retrovirale Proteaseinhibitoren<br />

Resistance-repellent retroviral protease<br />

inhibitors<br />

Inhibiteurs de la protéase rétrovirale<br />

résistants/répulsifs<br />

(71) Sequoia Pharmaceuticals, Inc., 401 Professional<br />

Drive, Suite 100, Gaithersburg, MD<br />

20879, US<br />

(72) Eissenstat, Michael, Frederick, MD Maryland<br />

21702, US<br />

Delahanty, Greg, Silver Spring, MD Maryland<br />

2<strong>09</strong>01, US<br />

Topin, Andrey, Highland, MD Maryland<br />

20777, US<br />

Rajendran, Gnana Ravi, Gaithersburg, MD<br />

Maryland 20877, US<br />

(74) Carpmaels & Ransford, One Southampton<br />

Row, London WC1B 5HA, GB<br />

(62) 05745707.9 / 1 750 696<br />

(51) A61K 31/335 (11) 2 422 781 A1<br />

C07D 231/56 C07D 311/74<br />

A61K 31/416 A61K 31/343<br />

A61K 31/353 A61K 31/665<br />

C07D 493/04 A61P 31/18<br />

(25) En (26) En<br />

(21) 11188135.5 (22) <strong>09</strong>.05.2005<br />

(84) AT BE BG CH CY CZ DE DK EE ES FI FR GB<br />

GR HU IE IS IT LI LT LU MC NL PL PT RO<br />

SE SI SK TR<br />

(30) 07.05.2004 US 568935 P<br />

(54) Resistenzabweisende retrovirale Proteaseinhibitoren<br />

Resistance-repellent retroviral protease<br />

inhibitors<br />

Inhibiteurs de la protéase rétrovirale<br />

résistants/répulsifs<br />

(71) Sequoia Pharmaceuticals, Inc., 401 Professional<br />

Drive, Suite 100, Gaithersburg, MD<br />

20879, US<br />

(72) Eissenstat, Michael, Frederick, MD Maryland<br />

21702, US<br />

Delahanty, Greg, Silver Spring, MD Maryland<br />

2<strong>09</strong>01, US<br />

Topin, Andrey, Highland, MD Maryland<br />

20777, US<br />

Rajendran, Gnana Ravi, Gaithersburg, MD<br />

Maryland 20877, US

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