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The Endocannabinoid System<br />
Endocannabinoids are molecules that bind to <strong>and</strong><br />
activate cannabinoid receptors. Unlike the cannabinoids<br />
found naturally in cannabis, endocannabinoids are<br />
produced naturally by cells in the human body.<br />
(Endo = Endogenous)<br />
The two major endocannabinoids are an<strong>and</strong>amide <strong>and</strong><br />
2-AG. These endocannabinoids are made from fat-like<br />
molecules within cell membranes <strong>and</strong> are synthesized<br />
on dem<strong>and</strong>.<br />
This means that they get made <strong>and</strong> used exactly when<br />
they are needed, rather than packaged <strong>and</strong> stored for<br />
later use like many other biological molecules.<br />
Metabolic Enzymes are enzymes that quickly destroy<br />
endocannabinoids once they are used. The two big<br />
enzymes are FAAH, which breaks down an<strong>and</strong>amide,<br />
<strong>and</strong> MAGL, which breaks down 2-AG.<br />
These enzymes are important because they ensure<br />
that endocannabinoids get used when they’re<br />
needed, but not for longer than necessary.<br />
THC & CBD: Whats the difference?<br />
THC<br />
Psychoactive<br />
Known for its High<br />
Appetite Stimulant<br />
Drowsiness<br />
Euphoria<br />
Combats<br />
Pain<br />
Cant<br />
Overdose<br />
CBD<br />
Non-Psychoactive<br />
Found in Hemp &<br />
Cannabis<br />
Anti-Inflammatory<br />
Neuro-Protective<br />
Anti-Anxiety
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