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The Endocannabinoid System<br />

The main function of the human<br />

endocannabinoid system is to help<br />

maintain homeostasis throughout<br />

your entire body.<br />

There are a few key pieces to the ECS<br />

Cannabinoid Receptors<br />

Endocannabinoids<br />

Metabolic Enzymes<br />

Cannabinoid Receptors are key to the endocannabinoid<br />

system in the sense that they are<br />

the communicator. These receptors transmit<br />

information about changing conditions to the<br />

inside of the cell.<br />

There are two major cannabinoid receptors:<br />

CB1 & CB2. These are not the only receptors,<br />

but they were the first ones discovered <strong>and</strong><br />

have remained the best studied.<br />

The CB1 receptor is expressed mainly in the brain or<br />

central nervous system, but also in the lungs, liver, <strong>and</strong><br />

kidneys.<br />

The CB2 receptor is expressed mainly in the immune<br />

system <strong>and</strong> in hematopoietic cells. They are also<br />

expressed on the peripheral nerve terminals, which<br />

play a role in the relief of pain.<br />

<strong>Health</strong> <strong>and</strong> <strong>Wellness</strong> Botanicals LLC does not sell or distribute any products that are in violation of the United States Controlled Substances Act (USA CSA). The company<br />

does sell, <strong>and</strong> distribute hemp-based products.<br />

FOOD AND DRUG ADMINISTRATION (FDA) DISCLOSURE<br />

These statements have not been evaluated by the FDA <strong>and</strong> are not intended to diagnose, treat, or cure any disease. Always check with your physician before starting a<br />

new dietary supplement program.

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