LightNeedle - RJ Laser
LightNeedle - RJ Laser LightNeedle - RJ Laser
Methods Near-infrared spectroscopy The NIRS method allows the evaluation of changes in cerebral oxygenation through the intact skull and is also gaining importance in acupuncture research because of its non-invasive approach [4-8]. The NIRO 300 Monitor (Hamamatsu Photonics, Japan) is a new instrument in this field of research. Parameters such as changes in oxyhemoglobin ( O 2Hb) and desoxyhemoglobin ( HHb) are determined by Lambert-Beer´s principle [4]. The system can measure the absolute value (µmol) of changes in parameters, but not the level (absolute concentration) at which these changes occur (in positive or negative direction). The measurement value is zero, as long as no change in concentration occurs. Placement of the sensor (emitter and near-infrared detectors) on the head with a silicone holder is easy and reproducible. Data output of O 2Hb and HHb were presented on a color LCD-Display and color printer. In addition to the spectroscopic method, non-invasive, standard monitoring parameters such as blood pressure (Cardiocap ® CC-104, Datex Medical Electronics, Hoevelaken, Netherlands) were determined before, during and after different manners of stimulation. Laserneedle ® stimulation The Laserneedle ® -technique represents a new, non-invasive method for optic stimulation of acupuncture points and was first described in literature in 2002 [9,10]. Laserneedle ® (Schikora D.: European Patent Nr. PCT/EP 01/08504) acupuncture allows the simultaneous stimulation of individual acupuncture point combinations [9,10]. Variations and combinations of acupuncture at different areas of the body, ear or hand, as performed particularly in this study are possible (compare Fig. 1). Details regarding this method can be found in preceding studies [9,10]. 3
Fig. 1: Test person during laserneedle stimulation and simultaneous registration of NIRS parameters. Right bottom: single active laserneedle and application device. Changes in near-infrared spectroscopic parameters in the frontal region of the brain were continuously registered and analyzed. Healthy volunteers, acupuncture, measurement procedure In this study, a total of 328 measurements on 88 healthy volunteers (50 female, 38 male) mean age 25.7 + 4.0 (⎺x + SD) years (19 - 38 years) were performed. The study protocol was approved by the ethics committee of the University of Graz (11- 017) and all test persons gave their written consent. None of the volunteers had 4
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Methods<br />
Near-infrared spectroscopy<br />
The NIRS method allows the evaluation of changes in cerebral oxygenation through<br />
the intact skull and is also gaining importance in acupuncture research because of<br />
its non-invasive approach [4-8].<br />
The NIRO 300 Monitor (Hamamatsu Photonics, Japan) is a new instrument in this<br />
field of research. Parameters such as changes in oxyhemoglobin ( O 2Hb) and<br />
desoxyhemoglobin ( HHb) are determined by Lambert-Beer´s principle [4]. The<br />
system can measure the absolute value (µmol) of changes in parameters, but not<br />
the level (absolute concentration) at which these changes occur (in positive or<br />
negative direction). The measurement value is zero, as long as no change in<br />
concentration occurs. Placement of the sensor (emitter and near-infrared detectors)<br />
on the head with a silicone holder is easy and reproducible. Data output of O 2Hb<br />
and HHb were presented on a color LCD-Display and color printer.<br />
In addition to the spectroscopic method, non-invasive, standard monitoring<br />
parameters such as blood pressure (Cardiocap ® CC-104, Datex Medical Electronics,<br />
Hoevelaken, Netherlands) were determined before, during and after different<br />
manners of stimulation.<br />
<strong>Laser</strong>needle ® stimulation<br />
The <strong>Laser</strong>needle ® -technique represents a new, non-invasive method for optic<br />
stimulation of acupuncture points and was first described in literature in 2002 [9,10].<br />
<strong>Laser</strong>needle ® (Schikora D.: European Patent Nr. PCT/EP 01/08504) acupuncture<br />
allows the simultaneous stimulation of individual acupuncture point combinations<br />
[9,10]. Variations and combinations of acupuncture at different areas of the body,<br />
ear or hand, as performed particularly in this study are possible (compare Fig. 1).<br />
Details regarding this method can be found in preceding studies [9,10].<br />
3