LightNeedle - RJ Laser

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ment A 1 of the ACA was exposed to ultrasonic waves at a depth of 58 to 88 mm. The flow direction in the ACA was opposite from the ipsilaterally applied probe. The PCA was exposed to ultrasonic waves between 60 and 78 mm and the flow direction in segment Pl was directed towards the probe. Near-infrared spectroscopy (NIRS) The NIRS method allows the monitaring of changes in cerebral oxygenation through the intact skull, and is gaining importance in acupuncture research because of its non i nvasiveness2,6, 17,28=-30,34,36,37. One equipment für this fjeld of research is the NIRO 300 Monitor (Hamamatsu Photonics, Japan). Measurement values such as changes in oxyhemoglobin (AO2Hb) and desoxyhemoglobin (AHHb) are determined by Lambert-Beer's Principle3,37. With this system, changes in parameters can be measured absolutely (Jlmolar), however, the niveau (absolute concentration) at which these changes (in positive ar negative direction) occur cannot be determined. As lang as no change in concentration takes place, the measurement value is zero. Using a silicone holder, the application of the probe (emitter and near-infrared detectors) on the head is simple. Data reproduction of AO2Hb and AHHb was düne with a color LCD-display and color printer. 2 Neurological Research, 2003, Volume 25, Volunteers and procedure Twenty-two healthy volunteers, mean age 24.4 :f: 2.6 years (21-29 years) were examined with LDF and temperature monitoring. At the time of measurement, the volunteers were informed about the procedure, were not under influence of medication and gave their written consent. In addition, thermography imaging was performed on two volunteers. This study was approved by the Ethics Committee of the University of Graz, Austria (Laserneedle@-Stimulation; 13-048 ex 02/03). Continuous measurement of microcirculation parameters and temperature at the right hand were initiated, after a resting period of 10 min. When the 'steady-state' condition was reached, acupuncture point Hegu (Li.4) on the right hand was stimulated with a laserneedle@. After cleaning the skin with alcohol, the laserneedle@ was fixed at the acupuncture point with special adhesive tape. A semi-conductor with an emitting wavelength of 680 nm was used as light source. Laser intensity was rv60 mW. The LDF-tem~erature probe was applied 1 cm from the laserneedle .This distance was selected in the infrared range of 1 cm, based on the given geometric dimensions of the probe holder and the supposed optic penetration depth. In addition, temperature at the measurement point as weil as room temperature were determined for comparison.
a +-+ 2 min b c miR 10 min 20 min lasemeedle@-stimulation activ Effects of laserneedle@-stimulation: Gerhard Litscher d '..e I min e -.-+ 2 min Figure 2: Measurement profile and measuring times (a-e) before, during and after laserneedle\n1-acupuncture Figure 2a-e shows the different measurement times before, during and after laserneedle@ stimulation. In a further study series, flow profiles from the ACA and P CA, before, during and after acupuncture were registered continuously in the same 22 adult volunteers3. Two laserpuncture schemes were tested during two different measurements on each test person. The first scheme (Yingxiang, Hegu and Pianli, stimulated bilaterally) was used to influence the olfactory system according to the expectations of traditional Chinese medicine, the second scheme (Guangming, Taichong and Zhiyin, bilateral stimulation of all three points) to activate the optic system3, has already been documented in preliminary studies 1-3. Statistical analysis LDF-data were analysed with 'Friedman repeated measures ANOV A on ranks' using SigmaStat Oandel Scientific Corp., Erkrath, Germany). The Tukey test was used for post hoc analysis. Mean values before (a), during (b-d) and after (e) laserneedle@ acupuncture are shown graphically. Statistical significance was estab- lished at p< 0.05. Mean blood flow velocity (vm) in the left ACA as weil as Vm in the PCA were referred to as evaluative parameters for TCD-measurements. This data was analysed with 'one-way repeated measure ANOVA'. RESULTS Figure 3 shows the summary of results from the three parameters flux, as weil as hand and room temperature at different measurement times. Note the significant changes in flux (p= 0.005) as weil as the increase in temperature at the measuring point (p= 0.02). Even 2 min after discontinuing laser stimulation (measurement time e), the flux was no longer significant, however markedly higher compared to the initial value. Temperature at the stimulation point (distance "",1 cm) showed an obvious increase, which reached its maximum at measurement time d. The nearly constant room temperature was registered simultaneously as a com- parative parameter. Figure 4 shows a typical example of Vm jncrease in the ACA during laserneedle@-stjmulation. Figure 5 (middle and lower sectjons) summarizes the TCD-results from all 22 volunteers and both laserpuncture schemes. When usjng laserpuncture scheme A, Vm increases significantly (p < 0.001) during stimulatjon (b-d) in the ACA and at the end of the test (e) is stjll higher than before laserneedle@-acupuncture (a). At the same time, no significant changes jn Vm in the PCA occurred. However, durjng optjc stjmulation of the acupuncture points jn scheme B, a signjfjcant (p< 0.002) increase in Vm in the PCA without signjficant simultaneous changes jn the ACA, took place. A frontal derivation of near-jnfrared spectroscopic parameters js shown jn Figure 6. DISCUSSION Laser Doppler technology js a suitable method for determinjng concentratjon and velocjty of moving blood cells in surface vessels. Penetratjon depth is Ijmjted to about 1 mm. Laser Ijght js usually transferred to the derivation point via optical fibres. Due to the Doppler effect, a frequency change in scattered Ijght occurs, whjch enables determination of e.g. flow velocjty. Currently, the possible advantages of this method jn acupuncture research are being investjgated2.3,21-23,26. Based on the results in this study, we see that the energy dose emjtted from a laserneedle@ jn 20 min at a distance of 1 cm, was able to warm local skin and subcutaneous tissues about 0.7°C (p= 0.02). Thus, stimulation wjth laserneedles@ is not only optical, but also thermic. It is interestjng that flux is signjficantly ~= 0.005) increased, 2 mjn after begjnnjng laserneedle stimulation. Laserneedle@ acupuncture leads to an jmprovement in local, peripheral microcirculation at the area where stjmulus applicatjon was done. This fact could be useful in case of dermatologic indications (p=0.005). The additional use of TCD enables continuous, noninvasjve monitorjng of blood flow in different cerebral vessels. The results presented in this study document a further important factor for characterising cerebral effects of laserneedle@ acupuncture. laserneedle@ stimulatjon of particular acupuncture points Neurological Research, 2003, Volume 2
Page 1 and 2: LightNeedle Photon energy in the fo
Page 3 and 4: The LightNeedle device works in con
Page 5 and 6: LightNeedle Therapy Choose the best
Page 7 and 8: LightNeedle Therapy Trigger points,
Page 9 and 10: LightNeedle Therapy Inner organs ca
Page 11 and 12: Abstracts Laser Acupuncture Effects
Page 13 and 14: Abstracts Laser Acupuncture Effects
Page 15 and 16: Abstracts Laser Acupuncture Laser-N
Page 17 and 18: 14 G. Litscher Methods Subjects The
Page 19 and 20: 16 100 80 ~ 60 m N I N I 40 20 O 35
Page 21 and 22: 18 G. Litscher colleagues [4] did c
Page 23 and 24: 38 that is shining on the skin does
Page 25 and 26: 40 FIG. 4. Laserneedle treatment of
Page 27 and 28: 42 16. Litscher G, Nemetz W, Smolle
Page 29 and 30: decisive importance for the therape
Page 31 and 32: The fMRI-study was based on a block
Page 33 and 34: Figures 2 and 3 document specific c
Page 35 and 36: Figure 6 (at the left) shows the hy
Page 37 and 38: Dr Lu Wang is a Doctor of Western a
Page 39: Gerhard Litscher Department 0( Biom
Page 45 and 46: 13 Litscher G, Wang L. Visualisieru
Page 47 and 48: after application of the needles or
Page 49 and 50: EFFECTS OF NEW NONINVASIVE LASERNEE
Page 51 and 52: Spectroscopy 16 (2002) 335-342 lOS
Page 53 and 54: Spectroscopy 16 (2002) 335-342 lOS
Page 55 and 56: E2 G. Litscher und D. Schikoru / Ne
Page 57 and 58: L\ ~mol G. Lit.l'cher and D. Schiko
Page 59 and 60: G. Litscher and D. .S.chiktJra / Ne
Page 61 and 62: SPECTROSCOPY: An International Jour
Page 63 and 64: presented. NIRS seems to be able to
Page 65 and 66: Fig. 1: Test person during lasernee
Page 67 and 68: Acupuncture points were needled wit
Page 69 and 70: Figures 4 and 5 show the mean value
Page 71 and 72: Fig. 5: Cerebral changes (generally
Page 73 and 74: A number of factors which can influ
Page 75 and 76: data analysis (all Department of Bi
Page 77 and 78: Photomedicine and Laser Surgery Vol
Page 79 and 80: LASER-NEEDLE THERAPY IN SONK 303 Th
Page 81 and 82: LASER-NEEDLE THERAPY IN SONK 305 di
Page 83: 16 Service & Support REIMERS & JANS

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