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Your horse’s care<br />

-<br />

Endocrine<br />

upsets<br />

When parts of the endocrine system fail<br />

to work properly, it can cause:<br />

Hypothyroidism is rare in adult horses,<br />

despite many conditions such as obesity,<br />

laminitis and insulin resistance being<br />

attributed to low concentrations of thyroid<br />

hormone. However, it may occur in foals<br />

born to mares who are fed inappropriate<br />

amounts of iodine during pregnancy.<br />

Thyroid adenoma You may have noticed<br />

that some older horses have thyroid<br />

glands that are very easy to feel. This is<br />

due to benign enlargement, which is really<br />

common and nothing to worry about.<br />

Pheochromocytoma This is a very rare<br />

type of tumour arising from the adrenal<br />

medulla. Some of these tumours will be<br />

‘functional’, which means they continue to<br />

produce adrenaline. The signs seen in horses<br />

therefore mimic situations where high levels<br />

of adrenaline are produced. Horses may have<br />

a high heart rate, increased breathing rate,<br />

anxiety, profuse sweating, dilated pupils,<br />

colic due to reduced intestinal motility and<br />

high blood sugar. While surgery to remove<br />

the adrenal gland would often be curative,<br />

the complexity of the surgery means that<br />

euthanasia is the more likely outcome.<br />

Primary hyperparathyroidism This occurs<br />

when the chief cells in the parathyroid<br />

secrete excessive amounts of parathyroid<br />

hormone and no longer respond to the<br />

negative feedback of calcium. The<br />

increased secretion is due to growth of a<br />

parathyroid adenoma, or parathyroid<br />

hyperplasia (over-growth of the gland). This<br />

results in increased blood calcium levels<br />

and, as this involves removing calcium from<br />

bones, the bones suffer as a consequence.<br />

Some older horses have<br />

enlarged thyroid glands,<br />

but generally this is<br />

nothing to worry about<br />

The bones of the face may become swollen,<br />

resulting in what’s known as ‘big head’ or<br />

‘rubber jaw’. Calcium removal from the long<br />

bones can lead to lameness, or even the risk<br />

of spontaneous fracture. Other signs include<br />

weight loss, lack of appetite, lethargy and colic.<br />

Diagnosis is via blood tests and the main<br />

treatment, which is curative, is removal of<br />

the enlarged parathyroid. However, as<br />

mentioned, finding the parathyroid, even<br />

when enlarged, is difficult. The best way to<br />

find it is through a nuclear scintigraphy scan<br />

to highlight the area of the neck where the<br />

parathyroid is located. Once this area is<br />

“Ovarian tumours<br />

may lead to stallionlike<br />

behaviour or<br />

persistent oestrus”<br />

Excessive calcium<br />

in the blood can<br />

result in lameness or<br />

spontaneous fractures<br />

narrowed down, the exact location can be<br />

pinpointed using ultrasonography. At this<br />

point, surgical removal may be possible.<br />

Ovarian tumour Granulosa cell tumours<br />

are the most common tumours of the<br />

reproductive tract of the mare. They can<br />

occur in mares of any age and may lead to<br />

behavioural changes, with either stallion-like<br />

behaviour or persistent oestrus/anoestrus.<br />

In other cases, behaviour is normal, but<br />

colic signs may occur. Diagnosis is based on<br />

blood testing for hormone levels, alongside<br />

palpation of the ovary per rectum and<br />

ultrasonography. Once the abnormal ovary is<br />

identified, it can be surgically removed, with<br />

a good prognosis. Surgery is most commonly<br />

performed laparoscopically (keyhole<br />

surgery) under standing sedation.<br />

92 your horse August 2019 www.yourhorse.co.uk

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