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Diagnostic Ultrasound - Abdomen and Pelvis

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Enlarged Kidney<br />

– Nonneoplastic causes: Dehydration <strong>and</strong> fever in<br />

children; hypercoagulability <strong>and</strong> nephrotic syndrome<br />

in adults<br />

– Renal enlargement with ↓ echogenicity, renal vein<br />

thrombus ± collaterals<br />

– Unilateral > bilateral<br />

○ Acute Renal Infarction<br />

– Embolic or traumatic arterial occlusion<br />

– Unilateral flank pain<br />

– Normal or enlarged kidneys with wedge-shaped<br />

defect on color Doppler<br />

○ Acute Cortical Necrosis<br />

– Caused by abruptio placentae, postpartum<br />

hemorrhage, shock, sepsis, <strong>and</strong> toxins<br />

– Results from microvascular thrombosis with cortical<br />

ischemia<br />

– Bilateral enlarged echogenic kidneys with hypoechoic<br />

subcapsular rim<br />

• Renal Abscess<br />

○ Solitary or multiple thick-walled intrarenal cystic lesions<br />

in the setting of infection<br />

○ More common in patients with diabetes mellitus, drug<br />

abuse, vesicoureteral reflux, renal calculi<br />

• Pyonephrosis<br />

○ Swollen obstructed kidney with debris or dependent<br />

echoes in collecting system<br />

• Perinephric Fluid Collections<br />

○ May represent abscess, blood, urine, <strong>and</strong> lymph<br />

○ May mimic large renal mass or compress the kidney<br />

causing "page kidney"<br />

• Renal Trauma<br />

○ Perirenal <strong>and</strong> renal hematomas, renal fracture, contusion<br />

Helpful Clues for Less Common Diagnoses<br />

• HIV Nephropathy<br />

○ Normal or enlarged kidneys<br />

○ Typically increased echogenicity with decreased<br />

corticomedullary differentiation<br />

○ Later small<br />

• Autosomal Dominant Polycystic Kidney Disease (ADPKD)<br />

○ Usually presents in adulthood<br />

○ Bilateral large kidneys with innumerable cysts of varying<br />

sizes that distort normal renal architecture<br />

• Multicystic Dysplastic Kidney (MDK)<br />

○ Multiple noncommunicating renal cysts of varying size<br />

with echogenic intervening parenchyma<br />

○ Initially enlarged kidney, later atrophy<br />

○ Association with contralateral renal disease common<br />

• Horseshoe Kidney<br />

○ Lower poles joined by isthmus of functioning renal tissue<br />

or fibrous b<strong>and</strong><br />

○ Lower in position with medially deviated lower poles<br />

• Crossed Fused Renal Ectopia<br />

○ Enlarged kidney with malrotation<br />

○ Absence of contralateral kidney<br />

Helpful Clues for Rare Diagnoses<br />

• Autosomal Recessive Polycystic Kidney Disease (ARPKD)<br />

○ Detected in utero or in infancy<br />

○ Bilaterally enlarged kidneys with increased echogenicity<br />

<strong>and</strong> multiple tiny cysts<br />

• Renal Lymphoma<br />

○ Focal or diffuse renal enlargement: Unilateral or bilateral<br />

○ Infiltrative: Diffuse renal enlargement with disruption of<br />

internal architecture<br />

○ Perirenal soft tissue rind<br />

• Renal Leukemia<br />

○ Gross renal involvement uncommon<br />

○ Symmetrically enlarged kidneys with distorted central<br />

sinus <strong>and</strong> ↓ corticomedullary differentiation<br />

• Xanthogranulomatous Pyelonephritis<br />

○ Pelvicalyceal obstruction by stone, (usually staghorn)<br />

○ Diffuse unilateral renal enlargement with echogenic<br />

debris in dilated calyces <strong>and</strong> cortical thinning<br />

○ Diabetes, recurrent urinary tract infections,<br />

immunocompromise<br />

• Renal Amyloidosis<br />

○ Abnormal protein deposition in kidneys<br />

• Renal Tuberculosis<br />

○ Dilated calyces <strong>and</strong> granulomatous abscesses<br />

Differential Diagnoses: Kidney<br />

Hydronephrosis<br />

Acute Pyelonephritis<br />

(Left) Longitudinal ultrasound<br />

of a markedly enlarged right<br />

kidney with severe<br />

hydronephrosis ſt,<br />

hydroureter <strong>and</strong> cortical<br />

thinning st in a patient with a<br />

history of posterior urethral<br />

valves <strong>and</strong> severe reflux. Renal<br />

pelvis echoes could<br />

represent infection, blood, or<br />

cellular debris. (Right)<br />

Longitudinal ultrasound in a<br />

patient with acute<br />

pyelonephritis <strong>and</strong> diabetes<br />

shows an enlarged hypoechoic<br />

right kidney st with loss of<br />

corticomedullary<br />

differentiation.<br />

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