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Diagnostic Ultrasound - Abdomen and Pelvis

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Abnormal Bladder Wall<br />

□ Uterine carcinoma<br />

□ Vaginal carcinoma<br />

□ Ovarian carcinoma<br />

○ Loss of fat plane between the bladder wall <strong>and</strong> the<br />

adjacent pelvic neoplasm<br />

○ May have direct intramural <strong>and</strong> intralesional extension<br />

– May be associated with fistulous communication<br />

○ Color Doppler<br />

– Vascularity of tumor outside bladder cavity may be<br />

demonstrated<br />

Helpful Clues for Less Common Diagnoses<br />

• Fungal Cystitis<br />

○ C<strong>and</strong>ida albicans is most common organism<br />

○ May be associated with fungal ball within bladder<br />

• Tuberculous Cystitis<br />

○ Hematogenous spread of primary tubercular infection,<br />

usually lungs (caused by Mycobacterium tuberculosis)<br />

○ Secondary to renal ± ureteric involvement<br />

○ Earliest form of bladder tuberculous cystitis starts<br />

around ureteral orifice<br />

○ Typically low-volume bladder with diffuse wall thickening<br />

("thimble bladder") ± wall calcification<br />

○ Fibrotic changes near ureteric orifice result in<br />

vesicoureteric reflux<br />

○ Associated with localized or generalized pyonephrosis<br />

• Bladder Schistosomiasis (Bilharziasis of Bladder)<br />

○ Infection of urinary system by parasite Schistosoma<br />

hematobium<br />

○ Thick-walled fibrotic bladder<br />

○ Echogenic calcification within bladder wall<br />

○ Small capacity bladder with inability to completely empty<br />

○ ± hydronephrosis <strong>and</strong> hydroureter due to distal ureteric<br />

stricture<br />

○ Late complication<br />

– Squamous cell carcinoma of bladder<br />

○ Often difficult to differentiate from tuberculosis based<br />

on imaging<br />

• Emphysematous Cystitis<br />

○ Infection of the bladder wall by gas-forming bacterial or<br />

fungal organism<br />

– E. coli, Enterobacter aerogenes, Klebsiella pneumonia,<br />

Proteus mirabilis<br />

○ Echogenic foci within area of bladder wall thickening<br />

with ring-down artifact<br />

○ Plain radiograph or CT for confirmation<br />

• Invasion by Pelvic Inflammatory Disease<br />

○ Crohn disease: Inflamed bowel or fistula formation<br />

○ Sigmoid colonic diverticulitis<br />

○ Endometriotic pelvic implants<br />

– Diffuse of focal bladder wall thickening, surrounding<br />

inflammatory changes<br />

– Increased vascularity in the inflammatory tissue<br />

SELECTED REFERENCES<br />

1. Lee G et al: Cystitis: from urothelial cell biology to clinical applications.<br />

Biomed Res Int. 2014:473536, 2014<br />

2. Manack A et al: Epidemiology <strong>and</strong> healthcare utilization of neurogenic<br />

bladder patients in a US claims database. Neurourol Urodyn. 30(3):395-401,<br />

2011<br />

3. Manik<strong>and</strong>an R et al: Hemorrhagic cystitis: A challenge to the urologist. Indian<br />

J Urol. 26(2):159-66, 2010<br />

4. Vikram R et al: Imaging <strong>and</strong> staging of transitional cell carcinoma: part 1,<br />

lower urinary tract. AJR Am J Roentgenol. 192(6):1481-7, 2009<br />

5. Figueiredo AA et al: Urogenital tuberculosis: update <strong>and</strong> review of 8961<br />

cases from the world literature. Rev Urol. 10(3):207-17, 2008<br />

6. Thomas AA et al: Emphysematous cystitis: a review of 135 cases. BJU Int.<br />

100(1):17-20, 2007<br />

7. Wein AJ et al: Overactive bladder: a better underst<strong>and</strong>ing of<br />

pathophysiology, diagnosis <strong>and</strong> management. J Urol. 175(3 Pt 2):S5-10,<br />

2006<br />

8. Wong-You-Cheong JJ et al: From the archives of the AFIP: Inflammatory <strong>and</strong><br />

nonneoplastic bladder masses: radiologic-pathologic correlation.<br />

Radiographics. 26(6):1847-68, 2006<br />

9. Abrams P: Bladder outlet obstruction index, bladder contractility index <strong>and</strong><br />

bladder voiding efficiency: three simple indices to define bladder voiding<br />

function. BJU Int. 84(1):14-5, 1999<br />

Differential Diagnoses: Urinary Tract<br />

Underfilled/Underdistended Bladder<br />

Normal Trigone<br />

(Left) Transverse<br />

transabdominal ultrasound<br />

shows an apparent uniformly<br />

thickened wall of an<br />

underdistended bladder ſt.<br />

The bladder wall was normal<br />

after optimal distension.<br />

(Right) Transverse<br />

transabdominal ultrasound<br />

shows a focal thickening st at<br />

the interureteric ridge<br />

(trigone), a normal finding.<br />

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