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Diagnostic Ultrasound - Abdomen and Pelvis

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Bartholin Cyst<br />

TERMINOLOGY<br />

Definitions<br />

• Bartholin gl<strong>and</strong>s (or greater vestibular gl<strong>and</strong>s) are mucussecreting<br />

gl<strong>and</strong>s located in vulvar vestibule, just lateral <strong>and</strong><br />

inferior to vaginal introitus<br />

• Drain via narrow duct 2.5 cm in length<br />

• Cystic dilatation of Bartholin gl<strong>and</strong> occurs secondary to<br />

duct obstruction<br />

IMAGING<br />

General Features<br />

• Best diagnostic clue<br />

○ Palpable, <strong>and</strong> sometimes visible mass lateral <strong>and</strong> inferior<br />

to vaginal introitus<br />

○ Most common vulvar cystic mass<br />

○ Size ranges 1-4 cm<br />

• Location<br />

○ Posterolateral distal vaginal wall, medial to labia minora,<br />

<strong>and</strong> at level of introitus<br />

Ultrasonographic Findings<br />

• Grayscale ultrasound<br />

○ Cystic structure: Anechoic to mixed echogenicity if<br />

complicated by hemorrhage or infection; may contain<br />

septations<br />

○ Thick walled if infected<br />

• Power Doppler<br />

○ No internal vascularity, may see reactive hyperemia<br />

around Bartholin abscess<br />

MR Findings<br />

• T1WI<br />

○ Low signal fluid if uncomplicated, signal may ↑ with<br />

infection or hemorrhage<br />

• T2WI<br />

○ High signal fluid if uncomplicated, proteinaceous fluid<br />

may be lower signal than simple fluid<br />

Imaging Recommendations<br />

• Protocol advice<br />

○ Clinical diagnosis: Imaging generally not required unless<br />

complications suspected<br />

CT Findings<br />

• Hypo- to hyperdense cystic lesion near vaginal introitus<br />

○ Any solid component within should raise concern for<br />

malignancy<br />

DIFFERENTIAL DIAGNOSIS<br />

Other Labial Masses<br />

• Sebaceous cyst: Epidermal inclusion cysts, may become<br />

infected, respond well to incision <strong>and</strong> drainage<br />

• Thrombophlebitis or other infections<br />

• Hematoma: Straddle injury, abuse<br />

• Tumors: Rare, usually clinically obvious<br />

• Endometriosis/endometrioma<br />

Vulval Varices<br />

• Associated with pelvic congestion syndrome<br />

• Throughout vulva, not limited to vestibule<br />

Gartner Duct Cyst<br />

• Similar in appearance but in anterolateral wall of proximal<br />

vagina<br />

Skene Gl<strong>and</strong> Cyst<br />

• Periurethral in origin <strong>and</strong> separate from vaginal wall<br />

PATHOLOGY<br />

General Features<br />

• Etiology<br />

○ Obstruction of normal Bartholin gl<strong>and</strong> duct<br />

Microscopic Features<br />

• Body of gl<strong>and</strong> contains mucinous acini, duct has mixed<br />

squamous, mucinous, <strong>and</strong> transitional epithelial cells, <strong>and</strong><br />

duct orifice is mostly squamous cells<br />

CLINICAL ISSUES<br />

Presentation<br />

• Most common signs/symptoms<br />

○ Usually asymptomatic<br />

○ 1-4 cm, but can increase in size with repeated sexual<br />

stimulation<br />

○ Can result in dyspareunia<br />

○ Can become painful due to infection<br />

Demographics<br />

• Epidemiology<br />

○ Approximately 2% of women<br />

○ Can typically become symptomatic in 2nd to 3rd decade<br />

of life, but seen in all ages<br />

Natural History & Prognosis<br />

• Most are uncomplicated<br />

• If infected → Bartholin abscess<br />

○ Perineal pain, tender labial mass<br />

○ Multimicrobial or related to gonorrhea/chlamydia<br />

○ Increased size of preexisting mass<br />

• Carcinomas are rare (1% of all gynecologic malignancies<br />

<strong>and</strong> 0.1-0.5% of vulvar carcinomas)<br />

○ 80% are either squamous or adenocarcinoma<br />

Treatment<br />

• Abscess<br />

○ Incision/drainage ± silver nitrate cautery<br />

○ Marsupialization or excision for recurrent cases<br />

– Broad-spectrum antibiotics after surgical drainage<br />

○ Placement of Word catheter<br />

– Outpatient or ER treatment<br />

– Limited by tendency to dislodge<br />

SELECTED REFERENCES<br />

1. Hosseinzadeh K et al: Imaging of the female perineum in adults.<br />

Radiographics. 32(4):E129-68, 2012<br />

2. Kushnir VA et al: Novel technique for management of Bartholin gl<strong>and</strong> cysts<br />

<strong>and</strong> abscesses. J Emerg Med. 36(4):388-90, 2009<br />

3. Ergeneli MH: Silver nitrate for Bartholin gl<strong>and</strong> cysts. Eur J Obstet Gynecol<br />

Reprod Biol. 82(2):231-2, 1999<br />

4. Hill DA et al: Office management of Bartholin gl<strong>and</strong> cysts <strong>and</strong> abscesses. Am<br />

Fam Physician. 57(7):1611-6, 1619-20, 1998<br />

5. Yuce K et al: Outpatient management of Bartholin gl<strong>and</strong> abscesses <strong>and</strong> cysts<br />

with silver nitrate. Aust N Z J Obstet Gynaecol. 34(1):93-6, 1994<br />

Diagnoses: Female <strong>Pelvis</strong><br />

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