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Diagnostic Ultrasound - Abdomen and Pelvis

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Peritoneal Inclusion Cyst<br />

TERMINOLOGY<br />

Abbreviations<br />

• Peritoneal inclusion cyst (PIC)<br />

Synonyms<br />

• Peritoneal pseudocyst<br />

• Benign cystic mesothelioma<br />

• Inflammatory cysts of pelvic peritoneum<br />

• Benign encysted fluid<br />

• Multilocular inclusion cyst<br />

Definitions<br />

• Not true ovarian cyst<br />

• Peritoneal or ovarian fluid trapped by peritoneal adhesions<br />

IMAGING<br />

General Features<br />

• Best diagnostic clue<br />

○ Normal ovary surrounded or displaced by fluid<br />

containing septations<br />

• Location<br />

○ Adnexal<br />

– Unilateral 65%<br />

– Bilateral 35%<br />

○ Midline if large<br />

• Size<br />

○ Variable<br />

• Morphology<br />

○ Lacks true wall<br />

○ Boundaries defined by pelvic structures<br />

○ Displaces structures without invasion<br />

Ultrasonographic Findings<br />

• Grayscale ultrasound<br />

○ Irregular cystic lesion: Unilocular or multilocular<br />

○ Soft <strong>and</strong> deformable<br />

○ Lacks mass effect<br />

– Passive lesion conforming to shape of pelvis<br />

□ Lateral border from pelvic sidewall<br />

○ Anechoic content<br />

– Echoes with hemorrhage or proteinaceous debris<br />

○ Variable number <strong>and</strong> thickness of septa (in 81%)<br />

– Fine septations most common<br />

□ Mobile with transducer pressure<br />

□ "Flapping sail" sign<br />

– Thick septations with nodules possible<br />

○ Intact ovary present<br />

– Entrapped ovary<br />

□ Ovary surrounded by fluid <strong>and</strong> septations<br />

□ "Spider in web" appearance<br />

– Displaced ovary<br />

□ External/adjacent to PIC<br />

□ Along pelvic sidewall<br />

□ Stuck to pelvic organ<br />

– Distorted ovary<br />

□ May lose normal contour<br />

□ Pulled by adhesions but intact<br />

• Color Doppler<br />

○ Blood flow can be seen in septations, especially if thick<br />

CT Findings<br />

• Multiseptated pelvic fluid collection<br />

• Mass respects pelvic structure boundaries<br />

○ Pelvic sidewall as lateral boundaries<br />

○ Bladder, bowel, uterus, fallopian tubes serve as<br />

boundaries<br />

• Thin septations not seen by CT<br />

○ Mass appears unilocular<br />

• Thicker septations resolved by CT<br />

○ May enhance<br />

• Associated ovary often not seen<br />

• Useful for large PIC <strong>and</strong> for excluding malignant peritoneal<br />

disease<br />

MR Findings<br />

• Simple fluid characteristics<br />

○ Low signal on T1<br />

○ High signal on T2<br />

• Blood products sometimes present<br />

○ High signal on T1<br />

• Enhancement helps define borders <strong>and</strong> septa<br />

○ Walls of PIC formed by surrounding structures<br />

– Pelvic walls, pelvic organs, bowel loops<br />

○ No true cyst wall<br />

• MR may help find intact ovary if not seen by ultrasound<br />

Nonvascular Interventions<br />

• Therapeutic or diagnostic aspiration using transabdominal<br />

or transvaginal approach<br />

Imaging Recommendations<br />

• Best imaging tool<br />

○ Transvaginal ultrasound first-line to localize ovary <strong>and</strong><br />

exclude signs of malignancy<br />

○ MR most useful if PIC is large <strong>and</strong> normal ovaries cannot<br />

be found using ultrasound<br />

○ CT may be suggestive but less sensitive at locating<br />

ovaries<br />

• Protocol advice<br />

○ Suspect diagnosis in right clinical setting<br />

– Premenopausal patient with history of multiple pelvic<br />

surgeries<br />

○ Look for otherwise normal ovary surrounded by<br />

septated fluid collection<br />

– May be displaced to periphery of mass<br />

– Consider MR to find ovary<br />

○ Use transvaginal probe to displace pelvic structures<br />

– PIC is not invasive<br />

○ Exclude solid components to differentiate from cancer<br />

DIFFERENTIAL DIAGNOSIS<br />

Ovarian Cystic Neoplasm<br />

• Cystadenoma/cystadenocarcinoma<br />

• Separate normal ovary not seen<br />

• Unilocular or multilocular<br />

• Papillary projections, solid nodules<br />

• Thicker or irregular septa<br />

• ± ascites, ± calcification<br />

• Mass effect on adjacent structures<br />

Diagnoses: Female <strong>Pelvis</strong><br />

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