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Diagnostic Ultrasound - Abdomen and Pelvis

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Tubo-Ovarian Abscess<br />

836<br />

Diagnoses: Female <strong>Pelvis</strong><br />

– Wall <strong>and</strong> adjacent structures have increased<br />

enhancement<br />

– May contain gas, best seen on T2*<br />

DIFFERENTIAL DIAGNOSIS<br />

Endometrioma ± Rupture<br />

• Lack signs of infection, different clinical picture<br />

• Multiple <strong>and</strong> bilateral lesions common<br />

• Often ovarian<br />

○ ± tube involvement, ± other pelvic organ involvement<br />

• Round masses more often than tubular<br />

○ Diffuse low-level echoes<br />

○ Thick wall <strong>and</strong> nodularity common<br />

○ May have fluid-fluid levels<br />

Hemorrhagic Ovarian Cyst ± Rupture<br />

• Usually single thin-walled cystic structure in ovary, separate<br />

from tube<br />

○ Internal debris or classic reticular echoes, which may also<br />

be seen in pelvis if ruptured<br />

○ Color Doppler: Halo of increased vascularity<br />

Paraovarian Cyst<br />

• Unilocular anechoic cyst, no endosalpingeal folds<br />

• Thin wall, adjacent to but separate from ovary<br />

Appendicitis<br />

• Inflamed blind-ending tubular structure in right lower<br />

quadrant<br />

○ If ruptured can see adjacent collections<br />

PATHOLOGY<br />

General Features<br />

• Etiology<br />

○ Infectious organism damages endocervical canal <strong>and</strong> its<br />

mucus barrier <strong>and</strong> ascends into upper genital tract<br />

– Coinfection with other organisms such as Escherichia<br />

coli, Haemophilus influenza, <strong>and</strong> Streptococcus are<br />

common<br />

– Extension of cervical columnar epithelium beyond<br />

cervix, <strong>and</strong> cervical mucosal changes in mid-cycle <strong>and</strong><br />

during menstruation, increases risk of ascending<br />

infection<br />

• Associated abnormalities<br />

○ Salpingitis can progress to hydrosalpinx or pyosalpinx if<br />

left untreated; late sequela is tubo-ovarian abscess<br />

CLINICAL ISSUES<br />

Presentation<br />

• Most common signs/symptoms<br />

○ Pelvic pain <strong>and</strong> cervical motion tenderness<br />

○ Fever, vaginal discharge<br />

• Other signs/symptoms<br />

○ Elevated WBC, ESR, or CRP<br />

○ Right upper quadrant pain rare<br />

– Fitz-Hugh-Curtis syndrome<br />

• Clinical profile<br />

○ Risk factors are similar to those for STDs <strong>and</strong> include<br />

exposure to STD, multiple sexual partners, use of illicit<br />

drugs or smoking, <strong>and</strong> young age<br />

Demographics<br />

• Age<br />

○ Women < 25 years at ↑ risk<br />

Natural History & Prognosis<br />

• Sequelae of fallopian tube scarring<br />

○ Tubal infertility<br />

○ Ectopic pregnancy<br />

○ Salpingitis isthmica nodosa<br />

– Diverticula of fallopian tube, mostly at isthmus<br />

• Chronic pelvic pain<br />

Treatment<br />

• Prompt antibiotic therapy<br />

• Goal of treatment is to cure acute state of infection with<br />

short-term antibiotics as well as prevent long-term<br />

sequelae<br />

• If adequate clinical response to outpatient antibiotic<br />

treatment is not achieved, patients may require parenteral<br />

antibiotics, additional diagnostic <strong>and</strong> laboratory testing, <strong>and</strong><br />

possibly surgical intervention<br />

• TOA may require drainage/surgery<br />

• Presence of IUD does not alter treatment, <strong>and</strong> empirical<br />

removal is not indicated<br />

DIAGNOSTIC CHECKLIST<br />

Image Interpretation Pearls<br />

• Acute PID may have subtle findings<br />

○ Pain will be disproportionate to findings<br />

○ Look for mild inflammatory change<br />

○ Look in posterior cul-de-sac for pus<br />

• TOA: Nonspecific complex cystic adnexal mass<br />

○ Use color Doppler to show increased flow<br />

• Abdominal ultrasound or CT important to assess extent of<br />

disease<br />

SELECTED REFERENCES<br />

1. Romosan G et al: The sensitivity <strong>and</strong> specificity of transvaginal ultrasound<br />

with regard to acute pelvic inflammatory disease: a review of the literature.<br />

Arch Gynecol Obstet. 289(4):705-14, 2014<br />

2. Kaproth-Joslin K et al: Imaging of female infertility: a pictorial guide to the<br />

hysterosalpingography, ultrasonography, <strong>and</strong> magnetic resonance imaging<br />

findings of the congenital <strong>and</strong> acquired causes of female infertility. Radiol<br />

Clin North Am. 51(6):967-81, 2013<br />

3. Romosan G et al: <strong>Ultrasound</strong> for diagnosing acute salpingitis: a prospective<br />

observational diagnostic study. Hum Reprod. 28(6):1569-79, 2013<br />

4. Chappell CA et al: Pathogenesis, diagnosis, <strong>and</strong> management of severe<br />

pelvic inflammatory disease <strong>and</strong> tuboovarian abscess. Clin Obstet Gynecol.<br />

55(4):893-903, 2012<br />

5. Rezvani M et al: Fallopian tube disease in the nonpregnant patient.<br />

Radiographics. 31(2):527-48, 2011<br />

6. Moyle PL et al: Nonovarian cystic lesions of the pelvis. Radiographics.<br />

30(4):921-38, 2010<br />

7. Kim JY et al: Perihepatitis with pelvic inflammatory disease (PID) on MDCT:<br />

characteristic findings <strong>and</strong> relevance to PID. Abdom Imaging. 34(6):737-42,<br />

2009<br />

8. Potter AW et al: US <strong>and</strong> CT evaluation of acute pelvic pain of gynecologic<br />

origin in nonpregnant premenopausal patients. Radiographics. 28(6):1645-<br />

59, 2008<br />

9. Horrow MM: <strong>Ultrasound</strong> of pelvic inflammatory disease. <strong>Ultrasound</strong> Q.<br />

20(4):171-9, 2004<br />

10. Sexually Transmitted Diseases Treatment Guidelines, 2015

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