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Diagnostic Ultrasound - Abdomen and Pelvis

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Uterine Anomalies<br />

TERMINOLOGY<br />

Abbreviations<br />

• Müllerian duct anomalies (MDA)<br />

Synonyms<br />

• Uterine fusion anomalies<br />

Definitions<br />

• MDA: Series of uterine malformations resulting from<br />

abnormal development, fusion, or resorption of müllerian<br />

ducts<br />

○ Unicornuate, bicornuate, didelphys uterus ±<br />

cervical/vaginal malformation<br />

IMAGING<br />

General Features<br />

• Best diagnostic clue<br />

○ Abnormal configuration of endometrial cavity ±<br />

abnormal external contour of uterus<br />

Ultrasonographic Findings<br />

• Grayscale ultrasound<br />

○ Arcuate uterus<br />

– Most common MDA<br />

– Minimal indentation of fundal endometrium<br />

– Normal external uterine contour<br />

○ Septate uterus<br />

– 2nd most common MDA<br />

– 2 endometrial cavities, septum of variable length <strong>and</strong><br />

thickness<br />

□ Thin fibrous septum variably present<br />

– May be difficult to discern outer uterine contour:<br />

Imaging overlap with bicornuate uterus<br />

□ Convex outer uterine contour or cleft < 1 cm<br />

□ Intercornual angle < 75° suggests septate uterus<br />

○ Bicornuate uterus<br />

– 3rd most common MDA<br />

– 2 symmetric uterine horns, fused inferiorly<br />

– May be difficult to discern outer uterine contour:<br />

Imaging overlap with septate uterus<br />

□ Deep fundal cleft > 1 cm<br />

□ Intercornual angle > 105° suggests bicornuate<br />

uterus<br />

□ Intercornual distance > 4 cm favors bicornuate<br />

uterus<br />

– May have single cervix (unicollis) or duplication<br />

(bicollis)<br />

○ Unicornuate uterus<br />

– Curved <strong>and</strong> elongated banana-shaped single uterine<br />

horn <strong>and</strong> endometrium<br />

– Hypoplastic contralateral horn often present<br />

□ Hematometros (HM) when obstructed<br />

□ May or may not communicate with unicornuate<br />

horn<br />

○ Uterus didelphys<br />

– 2 separate noncommunicating divergent uterine<br />

horns<br />

– Deep fundal cleft<br />

– 2 cervices<br />

– Vaginal septum in 75%<br />

□ Hematometrocolpos (HC) if obstructed<br />

○ Müllerian agenesis or hypoplasia<br />

– Absent or small rudimentary uterus<br />

– ± hematometros<br />

○ DES uterus (T shaped)<br />

– Nonspecific appearance on 2D US<br />

• 3D<br />

○ Vital for correct diagnosis of MDA<br />

– True coronal plane allows for better sonographic<br />

evaluation of uterine fundal contour<br />

MR Findings<br />

• Appearance dependent upon MDA type<br />

• T2WI: Best for visualizing outer uterine contour, zonal<br />

anatomy<br />

• T1WI: High signal endometrium indicates hematometros<br />

when obstructed<br />

CT Findings<br />

• MPR images can demonstrate outer uterine contour <strong>and</strong><br />

endometrial cavity but not study of choice<br />

Fluoroscopic Findings<br />

• Hysterosalpingography: Variable appearance of uterine<br />

cavity/cavities depending upon MDA type<br />

○ Limited as outer uterine contour not visible<br />

Imaging Recommendations<br />

• Best imaging tool<br />

○ <strong>Ultrasound</strong> as initial imaging test<br />

○ MR to clarify anatomy, relationship of pelvic organs<br />

– Better than ultrasound in defining uterine contour,<br />

identifying rudimentary uterine horns<br />

• Protocol advice<br />

○ <strong>Ultrasound</strong><br />

– 3D essential to evaluate uterine fundal contour<br />

– Limited until puberty, secondary to small uterine size<br />

○ MR<br />

– T1 <strong>and</strong> T2WI to evaluate anatomy, blood products<br />

□ True coronal images of uterus to evaluate fundal<br />

contour<br />

– Include renal fossae on coronal views<br />

DIFFERENTIAL DIAGNOSIS<br />

Imperforate Hymen<br />

• Uterus/vagina distended with mucous secretions or blood<br />

• Not associated with MDA<br />

• Need to differentiate from low transverse vaginal septum<br />

Cervical Stenosis<br />

• Can cause obstruction <strong>and</strong> distortion of endometrial cavity,<br />

mimicking MDA<br />

Pyometra<br />

• Associated with fever, elevated white cell count<br />

• Clinical diagnosis as complex fluid on imaging, may be pus<br />

or blood<br />

PATHOLOGY<br />

General Features<br />

• Etiology<br />

Diagnoses: Female <strong>Pelvis</strong><br />

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