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Diagnostic Ultrasound - Abdomen and Pelvis

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Allograft Hydronephrosis<br />

TERMINOLOGY<br />

Definitions<br />

• Dilated renal pelvis <strong>and</strong> calyces, usually secondary to<br />

obstruction<br />

○ ±hydroureter<br />

IMAGING<br />

General Features<br />

• Best diagnostic clue<br />

○ Dilated fluid-filled renal pelvis <strong>and</strong> calyces, persisting<br />

when bladder is empty<br />

• Location<br />

○ Over 90% at ureterovesical anastomosis <strong>and</strong> distal 1/3 of<br />

ureter<br />

Ultrasonographic Findings<br />

• Grayscale ultrasound<br />

○ Fluid-filled dilatation of renal pelvis branching into<br />

dilated calyces<br />

○ Hydroureter may be present, producing avascular<br />

tubular structure arising from renal hilum <strong>and</strong> extending<br />

toward bladder<br />

○ Note that distended bladder may cause functional<br />

obstruction or reflux resulting in hydronephrosis<br />

– Repeat scan with bladder empty<br />

○ Low-level echoes within lumen suggest pus<br />

(pyonephrosis) or blood (hemonephrosis)<br />

– Clot may also be present in ureter <strong>and</strong> bladder<br />

– Debris from infection may layer dependently<br />

○ Highly echogenic shadowing intraluminal structures<br />

represent stones<br />

– However, small stones may be very difficult to detect<br />

○ Highly echogenic, weakly shadowing masses suggest<br />

fungal balls<br />

○ <strong>Ultrasound</strong> is sensitive <strong>and</strong> specific for hydronephrosis<br />

○ <strong>Ultrasound</strong> may be limited for site of obstruction <strong>and</strong><br />

cannot providefunctional information<br />

• Color Doppler<br />

○ Useful to distinguish hilar vessels from dilated renal<br />

pelvis<br />

○ Use Color Doppler to distinguish clot or debris from solid<br />

tumor<br />

– Useful to demonstrate tiny vessels within urothelial<br />

tumors<br />

○ Elevated resistive index (RI) > 0.7 may occur in<br />

obstructive uropathy, but RI is nonspecific <strong>and</strong> rarely<br />

diagnostic<br />

○ "Twinkling" artifact allows confident diagnosis of<br />

calculus<br />

Nonvascular Interventions<br />

• Antegrade nephrostogram is gold st<strong>and</strong>ard in<br />

differentiating fixed from transient obstruction <strong>and</strong> for<br />

localizing site of obstruction<br />

• Invasive test requiring direct puncture of lateral calyx <strong>and</strong><br />

injection of iodinated contrast medium into collecting<br />

system<br />

• Usually combined with ultrasound guidance to access<br />

collecting system<br />

• Insertion of percutaneous nephrostomy catheter allows<br />

decompression of urine until definitive therapy, which can<br />

be performed through same access<br />

• Antegrade pyelography not performed in acute infection<br />

CT Findings<br />

• Use of iodinated contrast limited by poor renal function<br />

• More sensitive for fluid collections <strong>and</strong> calculi<br />

• CT nephrostography useful for delineation of stricture<br />

length <strong>and</strong> surrounding pathology<br />

MR Findings<br />

• T2WI<br />

○ High signal in fluid-filled pelvis <strong>and</strong> calyces<br />

○ Highly sensitive for fluid collection <strong>and</strong> allows<br />

differentiation between hydronephrosis <strong>and</strong> renal cysts<br />

○ Comprehensive high-resolution evaluation of entire<br />

urinary tract, including distal to obstruction<br />

– Localization of obstruction is superior to ultrasound<br />

○ Fast sequences allow diagnostic study in poorly<br />

cooperative patients<br />

• MR urogram (MRU) can be performed without contrast<br />

(T2WI) or with contrast (T1WI C+ FS)<br />

○ Avoids potential side effects of iodinated contrast<br />

medium administration but with risk for nephrogenic<br />

systemic fibrosis in poor renal function<br />

• Functional MR techniques not yet in wide clinical use<br />

Nuclear Medicine Findings<br />

• Tc-99m MAG3 renogram<br />

• Can differentiate true obstruction from nonobstructive<br />

dilatation<br />

• Provides functional information<br />

Imaging Recommendations<br />

• Best imaging tool<br />

○ <strong>Ultrasound</strong> is first-line imaging modality for allograft<br />

dysfunction both in early postoperative period <strong>and</strong> later<br />

○ Sensitive <strong>and</strong> specific for hydronephrosis but may be<br />

limited for location <strong>and</strong> cause of obstruction<br />

• Protocol advice<br />

○ If bladder is distended, re-evaluate for hydronephrosis<br />

when empty<br />

○ Look for transition zone <strong>and</strong> cause for obstruction, such<br />

as fluid collection, stone, or clot<br />

○ Consider antegrade pyelography or MAG3 renogram to<br />

differentiate obstruction from dilatation<br />

○ MR or CT for level of obstruction (MR preferred [no<br />

ionizing radiation] but CT in wide use)<br />

DIFFERENTIAL DIAGNOSIS<br />

Nonobstructive Dilatation<br />

• May be seen early due to atony <strong>and</strong> denervation<br />

• Associated with distended bladder<br />

○ Resolves on bladder emptying<br />

Pyo- or Hemonephrosis<br />

• Dilated calyceal system filled with low-level echoes<br />

• Clinical picture important for diagnosis<br />

Ureteral Calculi<br />

• Typical echogenic shadowing stone<br />

Diagnoses: Kidney Transplant<br />

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