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Diagnostic Ultrasound - Abdomen and Pelvis

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Schistosomiasis, Bladder<br />

Diagnoses: Urinary Tract<br />

TERMINOLOGY<br />

• Bilharziasis, parasitic infection<br />

• Infection of urinary system by parasite Schistosoma<br />

hematobium<br />

IMAGING<br />

• Imaging findings mirror pathologic course<br />

○ Acute phase: Nodular bladder wall thickening<br />

○ Chronic phase: Contracted, fibrotic, thick-walled bladder<br />

with calcifications<br />

• Calcifications of bladder wall (4-56%)<br />

○ ± calcification of ureter (34%), seminal vesicle (late)<br />

○ Calcification best seen on NECT<br />

• Mucosal irregularity, inflammatory pseudopolyps of<br />

bladder<br />

• Ureteritis cystica, distal ureteric stricture<br />

• Noncompliant, small-capacity bladder with significant<br />

postvoid residual<br />

KEY FACTS<br />

TOP DIFFERENTIAL DIAGNOSES<br />

• Bladder calculi<br />

• Bladder carcinoma<br />

• Cystitis<br />

○ Emphysematous cystitis<br />

PATHOLOGY<br />

• Cercariae pass from snail (intermediate host) to water <strong>and</strong><br />

penetrate human skin<br />

• Pass into lymphatics, lungs, <strong>and</strong> liver <strong>and</strong> migrate to pelvic<br />

venous plexus → bladder wall vessels<br />

CLINICAL ISSUES<br />

• Endemic in Middle East, India, Africa, Central America, <strong>and</strong><br />

South America<br />

• Diagnosis is confirmed by identifying ova of parasite in<br />

urine<br />

• Squamous cell carcinoma of bladder is late complication<br />

(Left) Graphic shows a<br />

markedly thickened urinary<br />

bladder wall with<br />

inflammatory polyps ſt <strong>and</strong><br />

mural calcifications .<br />

Ureteritis cystica changes <br />

are present in the dilated right<br />

ureter. (Right) Transverse<br />

transabdominal ultrasound of<br />

the bladder shows mild diffuse<br />

wall thickening ſt with linear<br />

echogenicity in the wall st<br />

from subtle wall calcification<br />

in a patient with<br />

schistosomiasis.<br />

(Left) Longitudinal<br />

transabdominal ultrasound of<br />

the bladder shows diffuse wall<br />

thickening ſt with linear<br />

mucosal echogenicity st from<br />

calcification in a patient with<br />

schistosomiasis.(Courtesy E.<br />

Wassal, MD, <strong>and</strong> A Abdelaziz,<br />

MD.) (Right) Axial CECT shows<br />

diffuse bladder wall<br />

calcification ſt, consistent<br />

with chronic phase of<br />

schistosomiasis infection.<br />

548

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