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Diagnostic Ultrasound - Abdomen and Pelvis

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Portal Vein Occlusion<br />

Diagnoses: Liver<br />

TERMINOLOGY<br />

• Definition: Obstruction of portal vein due to thrombosis<br />

IMAGING<br />

• Color/spectral Doppler sonography<br />

○ Surveillance <strong>and</strong> initial diagnosis<br />

○ Absent blood flow within PV on color or spectral Doppler<br />

US<br />

○ Cavernous transformation of PV<br />

• CECT/MR<br />

○ Comprehensive evaluation: Extent of occlusion <strong>and</strong><br />

collateralization<br />

○ Search for etiology <strong>and</strong> underlying condition<br />

TOP DIFFERENTIAL DIAGNOSES<br />

• Hepatic vein/IVC occlusion<br />

• Splenic vein occlusion<br />

• False-positive PV occlusion<br />

• False-negative PV occlusion<br />

KEY FACTS<br />

• Nonocclusive thrombosis<br />

• Dilated bile duct<br />

PATHOLOGY<br />

• Etiology<br />

○ Thrombosis due to flow stasis, hypercoagulability,<br />

intraabdominal inflammation<br />

○ Tumor thrombus ordirect tumor invasion<br />

• Acute thrombosis<br />

○ Lumen filled with thrombus, diameter may be enlarged<br />

• Chronic thrombosis<br />

○ Lumen occlusion accompanied by cavernous<br />

transformation<br />

DIAGNOSTIC CHECKLIST<br />

• False-positive/-negative diagnoses are a problem<br />

○ Appropriate Doppler ultrasound technique essential<br />

(Left) Grayscale ultrasound of<br />

the liver shows mildly<br />

echogenic thrombus ſt in the<br />

main portal vein. (Right)<br />

Power Doppler ultrasound in<br />

the same patient confirms<br />

absent flow within the<br />

thrombosed main portal vein<br />

ſt. Note the presence of<br />

ascites as well as underlying<br />

liver cirrhosis, which is a risk<br />

factor for development of<br />

portal vein thrombosis.<br />

(Left) Grayscale ultrasound<br />

shows an echogenic,<br />

chronically thrombosed main<br />

portal vein <strong>and</strong> adjacent<br />

collateralized flow ſt<br />

(cavernous transformation of<br />

the portal vein). (Right) Color<br />

Doppler ultrasound in the<br />

same patient shows<br />

collateralized flow ſt in the<br />

porta hepatis in this patient<br />

with chronic portal vein<br />

thrombosis . Color Doppler<br />

signal is heterogeneous<br />

because portal vein collaterals<br />

are tortuous, resulting in flow<br />

going both towards as well as<br />

away from the transducer.<br />

264<br />

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