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Diagnostic Ultrasound - Abdomen and Pelvis

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Prostate<br />

○ Sac-like structures superolateral to prostate, lateral<br />

outpouchings of vas deferens<br />

○ Secrete fructose-rich fluid (energy source for sperm)<br />

○ Arterial supply: Vesiculodeferential artery (branch of<br />

superior vesical artery)<br />

– May have additional supply from inferior vesical artery<br />

○ Venous drainage into pelvic venous plexus<br />

○ Lymphatic drainage into external <strong>and</strong> internal iliac nodes<br />

• Ejaculatory ducts<br />

○ Located on either side of midline<br />

○ Formed by union of seminal vesicle duct <strong>and</strong> vas<br />

deferens<br />

○ Start at base of prostate <strong>and</strong> run forward <strong>and</strong> downward<br />

through gl<strong>and</strong> in CZ<br />

IMAGING ANATOMY<br />

Prostate<br />

• Transrectal ultrasound (TRUS)<br />

○ Normal TZ is typically uniformly more echogenic than<br />

inner gl<strong>and</strong><br />

○ Inner gl<strong>and</strong> (TZ <strong>and</strong> CZ) is often distinguishable from PZ<br />

– Heterogeneous TZ in BPH<br />

○ TRUS-guided biopsy generally recommended when<br />

patient's PSA level is elevated or abnormal digital rectal<br />

exam (DRE) (exception: When elevated PSA occurs with<br />

suspected prostatitis → repeat PSA 2-3 months later)<br />

– TRUS: Visual aid for systematic biopsy of entire<br />

prostate, estimate prostate volume<br />

– TRUS has become mainstay of many image-guided<br />

prostate interventions: Prostate biopsy,<br />

brachytherapy, cryotherapy, <strong>and</strong> high-intensity<br />

focused ultrasonography (HIFU) as well as BPH<br />

evaluation<br />

• Prostate volume measurement<br />

○ Prolate ellipse volume for 3 unequal axes:Width x height<br />

x length x 0.523<br />

○ 1 cc of prostate tissue ~ 1 g; prostate weighs ~ 20 g in<br />

young men<br />

○ Prostatic enlargement when gl<strong>and</strong> is > 40 g<br />

Seminal Vesicles <strong>and</strong> Vasa Deferentia<br />

• Cystic appearance on TRUS, should be symmetric<br />

ANATOMY IMAGING ISSUES<br />

Imaging Recommendations<br />

• Transducer<br />

○ 7-10 MHz rectal transducer (end-firing or transverse<br />

panoramic)<br />

○ 3.5-6 MHz curved linear transducer for transabdominal<br />

ultrasound<br />

○ Perform in at least 2 orthogonal planes (axial <strong>and</strong><br />

sagittal)<br />

• Patient position<br />

○ TRUS: Left lateral decubitus with flexed hips <strong>and</strong> knees<br />

or in lithotomy position<br />

○ Transabdominal ultrasound: Supine, using urinary<br />

bladder as acoustic window (transvesical)<br />

– Fluid intake to ensure bladder distension<br />

Imaging Pitfalls<br />

• Abnormal vascularity on power Doppler ultrasound may be<br />

seen in hypertrophy, inflammation, <strong>and</strong> cancer<br />

○ Useful for directing biopsy<br />

• Transabdominal ultrasound of prostate is limited to<br />

evaluation of prostate size<br />

Transrectal Biopsy of Prostate<br />

• Most transrectal transducers have needle guidance system<br />

• Periprostatic block with local anesthesia injected along<br />

neurovascular bundles; may also use anesthetic gel <strong>and</strong><br />

intraprostatic injection of local anesthetic<br />

• Complications<br />

○ Common: Hematuria, hematochezia, <strong>and</strong><br />

hematospermia<br />

○ Other: Acute prostatitis, UTI, sepsis<br />

CLINICAL IMPLICATIONS<br />

Function<br />

• Main function is to add nutritional secretions to sperm to<br />

form semen during ejaculation<br />

• Also plays role in controlling flow of urine; prostate muscle<br />

fibers are under control of involuntary nervous system <strong>and</strong><br />

contract to slow <strong>and</strong> stop urine<br />

Zonal Distribution of Prostatic Disease<br />

• Prostate adenocarcinomas<br />

○ 75% in PZ<br />

○ 20% in TZ<br />

○ 5% in CZ<br />

• BPH: Nodular stromal <strong>and</strong> epithelial hyperplasia in<br />

periurethral (preprostatic) gl<strong>and</strong>s <strong>and</strong> TZ<br />

○ Compresses CZ <strong>and</strong> PZ<br />

○ Can cause bladder outlet obstruction from urethral<br />

compression &/or increased smooth muscle tone along<br />

bladder neck, prostate, <strong>and</strong> urethra<br />

Spread of Prostate Carcinoma<br />

• Signs of extraprostatic extension of prostatic carcinoma<br />

○ Asymmetry of NVB<br />

○ Obliteration of rectoprostatic angle<br />

○ Irregular bulge in prostatic contour<br />

• Up to 80% of prostatic cancers in peripheral zone are<br />

hypoechoic<br />

SELECTED REFERENCES<br />

1. Chung B, et al: Anatomy of the lower urinary tract <strong>and</strong> male genitalia. In<br />

Campbell-Walsh Urology. 10th ed. Philadelphia: Saunders: 2012:33-70<br />

2. Trabulsi E, et at: Ultrasonography <strong>and</strong> biopsy of the prostate. In Campbell-<br />

Walsh Urology. 10th ed. Philadelphia: Saunders: 2012: 2735-2747<br />

3. Hammerich K, et al: Anatomy of the prostate gl<strong>and</strong> <strong>and</strong> surgical pathology of<br />

prostate cancer. In Prostate Cancer. Cambridge, UK: Cambridge University<br />

Press: 2009: 1-14<br />

4. Boczko J et al: Transrectal sonography in prostate evaluation. Radiol Clin<br />

North Am. 44(5):679-87, viii, 2006<br />

5. McLaughlin PW et al: Functional anatomy of the prostate: implications for<br />

treatment planning. Int J Radiat Oncol Biol Phys. 63(2):479-91, 2005<br />

6. McNeal JE. The zonal anatomy of the prostate. Prostate. 2(1):35-49, 1981<br />

Anatomy: <strong>Pelvis</strong><br />

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