Diagnostic Ultrasound - Abdomen and Pelvis

09.07.2019 Views

Abnormal Endometrium ○ Multiple effects include – Polyps – Endometrial hyperplasia – Reactivation of foci of adenomyosis – Cystic endometrial atrophy with subendometrial cysts – Endometrial carcinoma □ Endometrial cancer in patients taking tamoxifen is frequently in endometrial polyps Helpful Clues for Rare Diagnoses • Endometritis ○ In postpartum patient, painful enlarged uterus ○ In nonpregnant patient, associated with pelvic inflammatory disease ○ Elevated white blood cell count ○ Thick, heterogeneous endometrial contents ± gas in septic endometritis • Unopposed Estrogen Use ○ Estrogen use without progesterone → endometrial polyps, hyperplasia, and carcinoma • Polycystic Ovary Syndrome ○ Enlarged ovaries with multiple, small, peripheral follicles ○ Central stroma may be echogenic but not a necessary component for diagnosis ○ No dominant follicle ○ Diffuse endometrial thickening due to prolonged proliferative phase or endometrial hyperplasia Other Essential Information • Transvaginal scanning is best for evaluation of endometrium ○ Saline infused hysterosonography helpful to differentiate focal lesions from diffuse thickening ○ Diffuse thickening can be sampled with blind biopsy ○ Focal mass best assessed with hysteroscopic biopsy • In some patients, orientation of endometrial cavity is such that transabdominal scan allows for better insonation and evaluation of endometrium • Additionally fibroids or very large uteri may preclude assessment using transvaginal probes • In uterine duplication anomalies, each endometrium must be separately evaluated Alternative Differential Approaches • Solid or complex ovarian lesion in association with endometrial lesion ○ Estrogenic effect from granulosa cell tumor may produce endometrial hyperplasia or carcinoma ○ Estrogen secretion from thecoma → endometrial lesions ○ Synchronous ovarian and endometrial carcinoma ○ Endometrioid ovarian carcinoma resembles endometrial carcinoma, associated with endometrial hyperplasia or carcinoma ○ Metastatic disease to ovaries from endometrial carcinoma SELECTED REFERENCES 1. Van den Bosch T et al: Intra-cavitary uterine pathology in women with abnormal uterine bleeding: a prospective study of 1220 women. Facts Views Vis Obgyn. 7(1):17-24, 2015 2. Langer JE et al: Imaging of the female pelvis through the life cycle. Radiographics. 32(6):1575-97, 2012 3. Sakhel K et al: Sonography of adenomyosis. J Ultrasound Med. 31(5):805-8, 2012 4. Sofoudis C et al: Endometrial stromal sarcoma in a 29-year-old patient. Case report and review of the literature. Eur J Gynaecol Oncol. 33(3):328-30, 2012 5. Allison SJ et al: saline-infused sonohysterography: tips for achieving greater success. Radiographics. 31(7):1991-2004, 2011 6. Bennett GL et al: ACR appropriateness criteria(®) on abnormal vaginal bleeding. J Am Coll Radiol. 8(7):460-8, 2011 7. Salim S et al: Diagnosis and management of endometrial polyps: a critical review of the literature. J Minim Invasive Gynecol. 18(5):569-81, 2011 Differential Diagnoses: Female Pelvis Secretory Phase Endometrium Secretory Phase Endometrium (Left) Longitudinal US in a patient on day 24 of her menstrual cycle shows secretory phase endometrium ſt. The coapted walls of the cavity remain partially visible as a thin echogenic line . (Right) Longitudinal US in a patient late in her menstrual phase shows a thickened, slightly hyperechoic endometrium ſt consistent with the secretory phase. 1049

Abnormal Endometrium Differential Diagnoses: Female Pelvis (Left) The CT appearance of the endometrium is nonspecific. Low density was thought to represent fluid within an expanded endometrial cavity ; subsequent ultrasound confirmed normal secretory phase endometrium. (Right) US in the same patient shows a thickened echogenic endometrial complex ſt consistent with secretory phase endometrium, which corresponds to the hypodensity on the CT scan. There is no fluid present. Secretory Phase Endometrium Secretory Phase Endometrium (Left) Longitudinal US shows nonspecific endometrial thickening ſt in a patient with irregular vaginal bleeding. (Right) US obtained during saline infusion sonohysterography in the same patient shows distention of the endometrial cavity without focal lesions. Slight lobularity of the endometrial lining is a normal finding ("endometrial wrinkles"). Secretory Phase Endometrium Secretory Phase Endometrium (Left) Transverse color Doppler US in a patient status post recent medical abortion demonstrates a thickened endometrium ſt with vascular flow st, consistent with retained products of conception. (Right) Pulsed Doppler US in the same patient shows low-resistance flow, typical of but not specific for retained products of conception. Retained Products of Conception Retained Products of Conception 1050

Abnormal Endometrium<br />

Differential Diagnoses: Female <strong>Pelvis</strong><br />

(Left) The CT appearance of<br />

the endometrium is<br />

nonspecific. Low density was<br />

thought to represent fluid<br />

within an exp<strong>and</strong>ed<br />

endometrial cavity ;<br />

subsequent ultrasound<br />

confirmed normal secretory<br />

phase endometrium. (Right)<br />

US in the same patient shows<br />

a thickened echogenic<br />

endometrial complex ſt<br />

consistent with secretory<br />

phase endometrium, which<br />

corresponds to the<br />

hypodensity on the CT scan.<br />

There is no fluid present.<br />

Secretory Phase Endometrium<br />

Secretory Phase Endometrium<br />

(Left) Longitudinal US shows<br />

nonspecific endometrial<br />

thickening ſt in a patient with<br />

irregular vaginal bleeding.<br />

(Right) US obtained during<br />

saline infusion<br />

sonohysterography in the<br />

same patient shows distention<br />

of the endometrial cavity<br />

without focal lesions. Slight<br />

lobularity of the endometrial<br />

lining is a normal finding<br />

("endometrial wrinkles").<br />

Secretory Phase Endometrium<br />

Secretory Phase Endometrium<br />

(Left) Transverse color<br />

Doppler US in a patient status<br />

post recent medical abortion<br />

demonstrates a thickened<br />

endometrium ſt with vascular<br />

flow st, consistent with<br />

retained products of<br />

conception. (Right) Pulsed<br />

Doppler US in the same<br />

patient shows low-resistance<br />

flow, typical of but not specific<br />

for retained products of<br />

conception.<br />

Retained Products of Conception<br />

Retained Products of Conception<br />

1050

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