Diagnostic Ultrasound - Abdomen and Pelvis

09.07.2019 Views

Enlarged Uterus Leiomyoma Adenomyosis (Left) Longitudinal US shows an enlarged uterus secondary to multiple leiomyomas. Two are visible ſt on this image, with typical imaging findings including well-defined borders and internal heterogeneity and shadowing. The thin endometrium is visible centrally . (Right) Transabdominal sagittal ultrasound shows a uterus with adenomyosis. The posterior myometrium st is much thicker than the anterior myometrium ſt. The endometrium is normal . Differential Diagnoses: Female Pelvis Adenomyosis Cervical Stenosis (Left) Transverse US shows pseudothickening of the endometrium ſt and uterine enlargement. Alternating bands of shadowing and increased through transmission are typical of adenomyosis. (Right) Longitudinal US of the lower uterine segment shows expansion of the endometrial cavity ſt with echogenic material st, consistent with hematocolpos in this patient with cervical stenosis. Endometrial Cancer Cervical Mass (Left) Transverse US in the same patient shows a necrotic mass with peripheral color flow st. There is myometrial thinning ſt, suggesting deep muscle invasion. (Right) Longitudinal transvaginal ultrasound shows a large, lobulated, solid cervical mass ſt representing cervical carcinoma. There was no endometrial cavity fluid st. 1047

Abnormal Endometrium Differential Diagnoses: Female Pelvis DIFFERENTIAL DIAGNOSIS Common • Secretory Phase Endometrium • Pregnancy and Complications • Retained Products of Conception • Mimic of Endometrial Thickening ○ Submucosal Leiomyoma ○ Intramural Leiomyoma ○ Adenomyosis ○ Hematometra • Endometrial Polyps Less Common • Endometrial Hyperplasia • Endometrial Cancer • Tamoxifen-Induced Changes Rare but Important • Endometritis • Unopposed Estrogen Use • Polycystic Ovary Syndrome • Endometrial Stromal Sarcoma ESSENTIAL INFORMATION Key Differential Diagnosis Issues • Is patient postpartum? ○ Endometritis ○ Retained products of conception • Is thickening focal? ○ Endometrial polyps ○ Leiomyoma, submucosal ○ Endometrial cancer ○ Endometrial hyperplasia ○ Retained products of conception • Does patient have abnormal bleeding? ○ Endometrial polyps ○ Leiomyoma, submucosal ○ Leiomyoma, intramural ○ Endometrial hyperplasia ○ Endometrial cancer ○ Retained products of conception • Is endometrial-myometrial interface indistinct? ○ Endometrial cancer ○ Leiomyoma, submucosal ○ Adenomyosis Helpful Clues for Common Diagnoses • Secretory Phase Endometrium ○ After ovulation in second 1/2 of menstrual cycle, endometrium can be thick, heterogeneous, and echogenic ○ Follow-up early in subsequent menstrual cycle will show thin endometrium • Pregnancy and Complications ○ Positive urine/serum human chorionic gonadotropin – Normal early pregnancy – Miscarriage – Ectopic pregnancy – Hydatidiform mole, complete mole – Hydatidiform mole, partial mole • Retained Products of Conception ○ Focal endometrial echogenic lesion ○ Fluid ± clot ○ May have calcifications ○ May have low-resistance arterial flow, but lack of flow does not exclude diagnosis • Submucosal Leiomyoma ○ Submucosal lesions > 50% within endometrium ○ Iso- or hypoechoic well-marginated lesion ○ Less echogenic than endometrium ○ Posterior shadowing ○ Multiple feeding vessels • Intramural Leiomyoma ○ Not true endometrial lesion but can cause appearance of endometrial thickening ○ Iso- or hypoechoic lesion distorting or obscuring endometrium ○ Shadowing behind leiomyoma • Adenomyosis ○ Poor definition of endometrial myometrial interface makes it difficult to evaluate and measure endometrium ○ Look for streaky linear hypoechoic myometrial bands and subendometrial cysts ○ Asymmetric uterine enlargement ○ Tender uterus • Hematometra ○ Look for underlying cause of obstruction – Uterine duplication anomaly – Leiomyoma – Endometrial cancer – Cervical cancer – If thin surrounding endometrium and no obstructing lesion, cervical stenosis is diagnosis of exclusion • Endometrial Polyps ○ Focal endometrial lesion ○ Typically more echogenic than surrounding endometrium ○ May have internal cysts ○ Stalk with single feeding vessel ○ May have broad base ○ Frequently multiple ○ Smooth margins Helpful Clues for Less Common Diagnoses • Endometrial Hyperplasia ○ Peri- or postmenopausal woman ○ Association with polycystic ovarian syndrome ○ ± cystic spaces ○ Typically diffuse but may be focal • Endometrial Cancer ○ Early stage – Appears as focal endometrial lesion ○ Later stage – Invades myometrium, leads to indistinct endometrialmyometrial interface ○ Irregular thickened heterogeneous endometrium • Tamoxifen-Induced Changes ○ Paradoxical estrogenic effect on endometrium increases with ↑ dose and time of treatment 1048

Enlarged Uterus<br />

Leiomyoma<br />

Adenomyosis<br />

(Left) Longitudinal US shows<br />

an enlarged uterus secondary<br />

to multiple leiomyomas. Two<br />

are visible ſt on this image,<br />

with typical imaging findings<br />

including well-defined borders<br />

<strong>and</strong> internal heterogeneity<br />

<strong>and</strong> shadowing. The thin<br />

endometrium is visible<br />

centrally . (Right)<br />

Transabdominal sagittal<br />

ultrasound shows a uterus<br />

with adenomyosis. The<br />

posterior myometrium st is<br />

much thicker than the anterior<br />

myometrium ſt. The<br />

endometrium is normal .<br />

Differential Diagnoses: Female <strong>Pelvis</strong><br />

Adenomyosis<br />

Cervical Stenosis<br />

(Left) Transverse US shows<br />

pseudothickening of the<br />

endometrium ſt <strong>and</strong> uterine<br />

enlargement. Alternating<br />

b<strong>and</strong>s of shadowing <strong>and</strong><br />

increased through<br />

transmission are typical of<br />

adenomyosis. (Right)<br />

Longitudinal US of the lower<br />

uterine segment shows<br />

expansion of the endometrial<br />

cavity ſt with echogenic<br />

material st, consistent with<br />

hematocolpos in this patient<br />

with cervical stenosis.<br />

Endometrial Cancer<br />

Cervical Mass<br />

(Left) Transverse US in the<br />

same patient shows a necrotic<br />

mass with peripheral color<br />

flow st. There is myometrial<br />

thinning ſt, suggesting deep<br />

muscle invasion. (Right)<br />

Longitudinal transvaginal<br />

ultrasound shows a large,<br />

lobulated, solid cervical mass<br />

ſt representing cervical<br />

carcinoma. There was no<br />

endometrial cavity fluid st.<br />

1047

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