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Diagnostic Ultrasound - Abdomen and Pelvis

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Abdominal Lymph Nodes<br />

Anatomy: <strong>Abdomen</strong><br />

GROSS ANATOMY<br />

Overview<br />

• Major lymphatic vessels <strong>and</strong> nodal chains lie along major<br />

blood vessels (aorta, IVC, iliac)<br />

• Lymph nodes carry the same name as the vessel they<br />

accompany<br />

• Lymph from alimentary tract, liver, spleen, <strong>and</strong> pancreas<br />

passes along celiac, superior mesenteric chains to nodes<br />

○ Efferent vessels from alimentary nodes form intestinal<br />

lymphatic trunks<br />

○ Cisterna chyli (chyle cistern)<br />

– Formed by confluence of intestinal lymphatic trunks<br />

<strong>and</strong> right <strong>and</strong> left lumbar lymphatic trunks, which<br />

receive lymph from nonalimentary viscera, abdominal<br />

wall <strong>and</strong> lower extremities<br />

– May be discrete sac or plexiform convergence<br />

• Thoracic duct: Inferior extent is chyle cistern at the L1-2<br />

level<br />

○ Formed by convergence of main lymphatic ducts of<br />

abdomen<br />

○ Ascends through aortic hiatus in diaphragm to enter<br />

posterior mediastinum<br />

○ Ends by entering junction of left subclavian <strong>and</strong> internal<br />

jugular veins<br />

• Lymphatic system drains surplus fluid from extracellular<br />

spaces <strong>and</strong> returns it to bloodstream<br />

○ Important function in defense against infection,<br />

inflammation, <strong>and</strong> tumor via lymphoid tissue present in<br />

lymph nodes, gut wall, spleen <strong>and</strong> thymus<br />

○ Absorbs <strong>and</strong> transports dietary lipids from intestine to<br />

thoracic duct <strong>and</strong> bloodstream<br />

• Lymph nodes<br />

○ Composed of cortex <strong>and</strong> medulla<br />

○ Invested in fibrous capsule, which extends into the nodal<br />

parenchyma to form trabeculae<br />

○ Internal honeycomb structure filled with lymphocytes<br />

that collect <strong>and</strong> destroy pathogens<br />

○ Hilum: In concave side, with artery <strong>and</strong> vein, surrounded<br />

by fat<br />

Abdominopelvic Nodes<br />

• Preaortic nodes<br />

○ Celiac nodes: Drainage from gastric nodes, hepatic<br />

nodes, <strong>and</strong> pancreaticosplenic nodes<br />

○ Superior <strong>and</strong> inferior mesenteric nodes: Drainage from<br />

mesenteric nodes<br />

• Lateral aortic nodes<br />

○ Drainage from kidneys, adrenal gl<strong>and</strong>s, ureter, posterior<br />

abdominal wall, testes <strong>and</strong> ovary, uterus <strong>and</strong> fallopian<br />

tubes<br />

• Retroaortic nodes<br />

○ Drainage from posterior abdominal wall<br />

• External iliac nodes<br />

○ Primary drainage from inguinal nodes<br />

○ Flow into common iliac nodes<br />

• Internal iliac nodes<br />

○ Drainage from inferior pelvic viscera, deep perineum,<br />

<strong>and</strong> gluteal region<br />

○ Flow into common iliac nodes<br />

• Common iliac nodes<br />

○ Drainage from external iliac, internal iliac, <strong>and</strong> sacral<br />

nodes<br />

○ Flow into lumbar (lateral aortic) chain of nodes<br />

• Superficial inguinal nodes<br />

○ In superficial fascia parallel to inguinal ligament, along<br />

cephalad portion of greater saphenous vein<br />

○ Receive lymphatic drainage from superficial lower<br />

extremity, superficial abdominal wall, <strong>and</strong> perineum<br />

○ Flow into deep inguinal <strong>and</strong> external iliac nodes<br />

• Deep inguinal nodes<br />

○ Along medial side of femoral vein, deep to fascia lata <strong>and</strong><br />

inguinal ligament<br />

○ Receive lymphatic drainage from superficial inguinal <strong>and</strong><br />

popliteal nodes<br />

○ Flow into external iliac nodes<br />

IMAGING ANATOMY<br />

Overview<br />

• CT is test of choice for cancer staging<br />

• May be supplemented by PET/CT in select cancers<br />

• <strong>Ultrasound</strong> may be useful in children or thin adults<br />

○ Normal nodes are elliptical with echogenic fatty hilum<br />

<strong>and</strong> uniform hypoechoic cortex<br />

○ Normal lymph nodes rarely detected on abdominal<br />

ultrasound<br />

• Normal diameter of lymph node varies depending on<br />

location<br />

○ Short axis diameter<br />

– Abdominopelvic < 10 mm<br />

– Hepatogastric ligament < 8 mm<br />

– Retrocrural < 6 mm<br />

ANATOMY IMAGING ISSUES<br />

Imaging Recommendations<br />

• Transducer: 2-5 MHz or 5-9 MHz for thinner patients<br />

• Patient examined in supine position with < 4 hours of<br />

fasting to decrease bowel gas<br />

• Graded compression technique to clear overlying bowel<br />

loops<br />

CLINICAL IMPLICATIONS<br />

Clinical Importance<br />

• Nodal enlargement is nonspecific, may be neoplastic,<br />

inflammatory, or reactive<br />

• Normal-sized lymph nodes may harbor metastatic<br />

malignancy<br />

• Node morphology is more specific for pathology<br />

○ Abnormal nodes have replacement or loss of fatty hilum<br />

○ Look for central necrosis, cystic change, or calcification<br />

• Lymphoma<br />

○ Multiple enlarged hypoechoic or anechoic nodes<br />

• Metastatic lymphadenopathy<br />

○ More echogenic <strong>and</strong> heterogeneous nodes compared to<br />

lymphomatous nodes<br />

• Infectious/reactive lymphadenopathy<br />

○ Nonspecific sonographic features<br />

○ May contain necrotic centers in mycobacterial infection<br />

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