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Diagnostic Ultrasound - Abdomen and Pelvis

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Focal Testicular Mass<br />

– Most common testicular tumor in men older than 60<br />

years; multiple lesions; 50% of cases bilateral<br />

– Often large at time of diagnosis<br />

– Commonly occurs in association with disseminated<br />

disease<br />

– Ill-defined, predominantly hypoechoic lesions<br />

– Increased vascularity on color Doppler<br />

– Involvement of epididymis <strong>and</strong> spermatic cord is<br />

common<br />

– Hemorrhage or necrosis is rare<br />

○ Leukemia<br />

– Most often seen in children<br />

– Testis is often the 1st site of extramedullary relapse<br />

– Diffuse testicular infiltration appears diffusely<br />

hypoechoic with increased vascularity; may be<br />

indistinguishable from orchitis on ultrasound<br />

□ Clinical correlation with signs of inflammation may<br />

help identify orchitis<br />

○ Metastases are rare<br />

– Most common primaries include prostate, lung, <strong>and</strong> GI<br />

tract<br />

○ Testis is frequent site of recurrence in male patients with<br />

lymphoma <strong>and</strong> acute leukemia<br />

• Gonadal Stromal Tumor<br />

○ Bilateral in 3%<br />

– < 3 cm usually benign<br />

– > 5 cm usually malignant<br />

○ Leydig cell tumor<br />

– Small solid hypoechoic testicular mass<br />

– In larger tumor, hemorrhage or necrosis leads to<br />

heterogeneous echo pattern<br />

○ Sertoli cell tumor<br />

– Small hypoechoic mass<br />

– Solid <strong>and</strong> cystic components<br />

– Punctate calcification may be present; large calcified<br />

mass in calcifying Sertoli cell tumor<br />

– Hemorrhage may lead to heterogeneity<br />

○ Indistinguishable from other testicular tumors by<br />

ultrasound findings<br />

• Testicular Epidermoid Cyst<br />

○ Cystic cavity lined by stratified squamous epithelium<br />

○ Onion skin appearance on ultrasound due to alternating<br />

layers of keratin <strong>and</strong> desquamated squamous cells<br />

○ May have peripheral calcified rim<br />

• Testicular Adrenal Rests<br />

○ Described in patients with congenital adrenal hyperplasia<br />

○ May be associated with impaired spermatogenesis<br />

○ Usually bilateral hypoechoic lesions; typically located at<br />

the mediastinum testis<br />

○ If left untreated may lead to fibrosis <strong>and</strong> testicular<br />

destruction<br />

• Testicular Sarcoid<br />

○ Usually bilateral involvement of epididymii <strong>and</strong> testes<br />

○ Hypoechoic nodule(s)<br />

○ Associated chest findings on radiograph or CT may be<br />

helpful clue<br />

SELECTED REFERENCES<br />

1. Coursey Moreno C et al: Testicular tumors: what radiologists need to know--<br />

differential diagnosis, staging, <strong>and</strong> management. Radiographics. 35(2):400-<br />

15, 2015<br />

2. Piton N et al: Focal non granulomatous orchitis in a patient with Crohn's<br />

disease. Diagn Pathol. 10(1):39, 2015<br />

3. Rajkanna J et al: Large testicular adrenal rest tumours in a patient with<br />

congenital adrenal hyperplasia. Endocrinol Diabetes Metab Case Rep.<br />

2015:140080, 2015<br />

4. Thompson JP et al: Identify Before Orchiectomy: Segmental Testicular<br />

Infarct. <strong>Ultrasound</strong> Q. ePub, 2015<br />

5. Bhatt S et al: Imaging of non-neoplastic intratesticular masses. Diagn Interv<br />

Radiol. 2011 Mar;17(1):52-63. Epub 2010 Jun 30. Review. Erratum in: Diagn<br />

Interv Radiol. 17(4):388, 2011<br />

6. Gaur S et al: Spontaneous intratesticular hemorrhage: two case descriptions<br />

<strong>and</strong> brief review of the literature. J <strong>Ultrasound</strong> Med. 30(1):101-4, 2011<br />

7. Loberant N et al: Striated appearance of the testes. <strong>Ultrasound</strong> Q. 26(1):37-<br />

44, 2010<br />

8. Bhatt S et al: Role of US in testicular <strong>and</strong> scrotal trauma. Radiographics.<br />

28(6):1617-29, 2008<br />

9. Bhatt S et al: Sonography of benign intrascrotal lesions. <strong>Ultrasound</strong> Q.<br />

22(2):121-36, 2006<br />

10. Dogra V et al: Acute painful scrotum. Radiol Clin North Am. 42 (2): 349-63,<br />

2004<br />

11. Mazzu D et al: Lymphoma <strong>and</strong> leukemia involving the testicles: findings on<br />

gray-scale <strong>and</strong> color Doppler sonography. AJR Am J Roentgenol. 164(3):645-<br />

7, 1995<br />

Differential Diagnoses: Scrotum<br />

Testicular Carcinoma<br />

Orchitis (Epididymoorchitis)<br />

(Left) Sagittal color Doppler<br />

ultrasound of the right testis<br />

in a 30-year-old man shows a<br />

focal well-defined hypoechoic<br />

mass with increased<br />

vascularity. Associated<br />

testicular microliths ſt are<br />

noted. Pathologically, this was<br />

confirmed to be a seminoma.<br />

(Right) Sagittal color Doppler<br />

ultrasound of right testis in a<br />

22-year-old man with acute<br />

right scrotum shows a focal<br />

hypervascular hypoechoic<br />

mass . Associated overlying<br />

skin thickening <strong>and</strong><br />

complex hydrocele st are<br />

seen. Patient was found to<br />

have focal orchitis.<br />

1015

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