Surgical sealants and adhesives

RESEARCH REPORT 

MARCH - 2019 

SURGICAL SEALANTS AND ADHESIVES MARKET 

SEGMENTED BY PRODUCTS, BY CONSUMBLES, AND BY APPLICATION, SIZE, 

SHARE, GROWTH, TRENDS AND FORECASTS 2018-2023

Surgical sealant and adhesives Market 

Materials used for repairing injured tissues, binding the tissues together 

externally and internally after injury or surgery, strengthening surgical wounds 

and replacing common stitching practices are called Surgical sealants and 

adhesives. For wound closure such as staples and suture surgical sealants and 

adhesives are preferred over traditional methods because of their numerous 

advantages like efficacy, usability and safety in several situations in different 

tissues. 

Global Surgical Sealants and Adhesives Market size was around USD 205 million 

in 2018. It is expected to grow at a CAGR of 9.6 % to reach USD 361 million by 

2023. 

Rising incidence of various chronic disorders such as obesity and CVDs, high 

accident rates, growing need to manage blood loss in patients, increasing 

incidence of trauma, rising number of surgeries and augmenting geriatric 

population are the primary drivers of the market. Secondary factors include 

increasing uptake of technologically advanced products owing to the FDA and CE 

Mark approvals.Clinical data requirements for product approval are costly and to 

add to that the lack of reimbursements are the major restraints of this market. 

Further, lack of awareness and relatively lower disposable income are secondary 

factors hindering the growth of this market. 

The Global Surgical Sealants and Adhesives Market segmentation by product, by 

indication and by application. On the basis of product, Global Surgical Sealants 

and Adhesives market is classified into Natural/Biological Sealants and Adhesives 

and Synthetic and Semi-Synthetic Sealants and Adhesives. Natural/Biological 

Sealants and Adhesives is further segmented into type and origin. By type it is 

categorized into Polypeptide/Protein-based Sealants and Adhesives (Fibrin-based 

Adhesives, Gelatine-based Adhesives, Collagen-based Adhesives and Albuminbased 

Adhesives) and Polysaccharide-based Sealants and Adhesives 

(Polysaccharide-based Sealants and Adhesives and Other Polysaccharide-based 

Adhesives). By Origin it sub-segmented into Human Blood-based and Animalbased. 

Further, Synthetic and Semi-Synthetic Sealants and Adhesives has been 

categorized into Cyanoacrylates, Polyethylene glycol Hydrogels, Urethane-based 

Adhesives and Other Synthetic Adhesives. In the polypeptide sealants and 

adhesives category, the fibrin-based adhesives commanded the largest market 

share because of the wide range of applications of these sealants in surgical 

areas for example, cardiac, spleen surgeries, liver, colonic anastomosis, and 

seroma prevention after soft tissue dissections. 

Furthermore, the gelatine-based adhesives category is estimated to grow at the 

highest CAGR during the aforementioned forecast period because of their tensile 

strength, high elasticity and high-adhesive. Moreover, on the basis of indication, 

the market is segmented into Surgical Haemostasis, Tissue Sealing and Tissue 

Engineering. In addition, on the basis of application the market can be categorized 

into Central Nervous System (CNS) Surgeries, General Surgeries, Cardiovascular 

Surgeries, Orthopaedic Surgeries, Cosmetic Surgeries, Urological Surgeries, 

Pulmonary Surgeries, Ophthalmic Surgeries and Other Applications. 

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By geography, the Global Surgical Sealants and Adhesives market has been 

categorized into North America, Europe, Asia Pacific, Latin America, and Middle 

East & Africa. Presently, North America accounts for the largest market share 

closely followed by Europe while Asia Pacific has the highest CAGR. 

CryoLife, Inc. (U.S.), Johnson & Johnson (Ethicon, Inc., Baxter International, Inc. 

(U.S.), and C.R. Bard, Inc. (U.S.) held the key share of the surgical sealants and 

adhesives market and are likely continue to dominate the market between 2016 

and 2021. Some of the primary players operating in this market are Cohera 

Medical, Inc. (U.S.), Ocular Therapuetix, Inc. (U.S.), Vivostat A/S (Denmark), and 

Sealantis Ltd. (Israel), Medtronic plc (U.S.), Sanofi Group (France), B. Braun 

Melsungen AG (Germany). 

TABLE OF CONTE 

1.Introduction 

1.1 Market Definition 

1.2 Study Deliverables 

1.3 Base Currency, Base Year and Forecast Periods 

1.4 General Study Assumptions 

2. Research Methodology 

3. Overview 

2.1 Introduction 

2.2 Research Phases 

2.2.1 Secondary Research 

2.2.2 Primary Research 

2.2.3 Econometric Modelling 

2.2.4 Expert Validation 

2.3 Analysis Design 

2.4 Study Timeline 

3.1 Executive Summary 

3.2 Key Inferences 

3.3 Epidemology 



4. Drivers, Restraints, Opportunities, and Challenges Analysis 

(DROC) 

4.1 Market Drivers 

4.2 Market Restraints 

4.3 Key Challenges 

4.4 Current Opportunities in the Market 

5. Market Segmentation 

5.1 Technology 

5.2 Product 

5.1.1 Introduction 

5.1.2 Spinal Fusion and Fixation Technologies 

5.1.3 Vertebral Compression Fracture Treatment 

5.1.4 Motion Preservation/Non-Fusion Technologies 

5.1.5 Spinal Decompression 

5.1.6 Y-o-Y Growth Analysis, By Technology 

5.1.7 Market Attractiveness Analysis, By Technology 

5.1.8 Market Share Analysis, By Technology 


Devices 

Devices 

Devices 

5.2.2 Thoracic Fusion and Lumbar Fusion 

5.2.2.1 Posterior Thoracic Fusion and Lumbar Fusion 

5.2.2.2 Interbody Thoracic Fusion and Lumbar Fusion 

5.2.2.2.1 By Approach 

Devices 

5.2.2.2.1.1 Anterior Lumbar Interbody Fusion 



Devices 

Fusion Devices 

Devices 

5.2.2.2.1.2 Posterior Lumbar Interbody Fusion 

5.2.2.2.1.3 Transforaminal Lumbar Interbody 

5.2.2.2.1.4 Axial Lumbar Interbody Fusion 

5.2.2.2.2 By Material 

5.2.2.2.2.1 Non-Bone Interbody Fusion Devices 

5.2.2.2.2.2 Bone Interbody Fusion Devices 

Devices 

5.2.2.2.3 Anterior Thoracic Fusion and Lumbar Fusion 

5.2.2.3 Cervical Fusion Devices 

5.2.2.3.1 Anterior Cervical Fusion 

5.2.2.3.1.1 Anterior Cervical Plates 

5.2.2.3.1.2 Cervical Interbody Fusion Devices 

5.2.2.3.1.3 Anterior Cervical Screw Systems 

5.2.2.3.2 Posterior Cervical Fusion 

5.2.2.3.2.1 Posterior Cervical Plates 

5.2.2.3.2.2 Posterior Cervical Screws 

5.2.2.3.2.3 Posterior Cervical Rods 

5.2.2.4 Spine Biologics 

5.2.2.4.1 Demineralized Bone Matrix 

5.2.2.4.2 Bone Morphogenetic Proteins 

5.2.2.4.3 Bone Substitutes 

5.2.2.4.4 Machined Bones 

5.2.2.4.5 Cell-Based Matrices 

5.2.2.4.6 Allografts 



5.2.2.5 Vcf Treatment Devices 

5.2.2.5.1 Balloon Kyphoplasty Devices 

5.2.2.5.2 Vertebroplasty Devices 

5.2.2.6 Spinal Decompression 

5.2.2.6.1 Discectomy 

5.2.2.6.2 Laminoplasty, Laminectomy, and Laminotomy 

5.2.2.6.3 Foraminotomy and Foraminectomy 

5.2.2.6.4 Facetectomy 

5.2.2.6.5 Corpectomy 

5.2.2.7 Non-Fusion Devices 

5.2.2.7.1 Dynamic Stabilization Devices 

5.2.2.7.1.1 Interspinous Process Spacers 

5.2.2.7.1.2 Pedicle-Based Dynamic Rod Devices 

5.2.2.7.1.3 Facet Replacement Products 

5.2.2.7.2 Artificial Discs 

5.2.2.7.2.1 Artificial Cervical Discs 

5.2.2.7.2.2 Artificial Lumbar Discs 

5.2.2.7.3 Annulus Repair Devices 

5.2.2.7.4 Nuclear Disc Prostheses 

5.2.2.8 Spine Bone Stimulators 

5.2.2.8.1 Non-Invasive Spine Bone Stimulators 

Devices 

5.2.2.8.1.1 Pulsed Electromagnetic Field 

5.2.2.8.1.2 Cc and Cmf Devices 

5.2.2.8.2 Invasive Spine Bone Stimulators 

5.2.3 Y-o-Y Growth Analysis, By Product 



5.2.4 Market Attractiveness Analysis, By Product 

5.2.5 Market Share Analysis, By Product 

5.3 Type of Surgery 


5.3.2 Open Surgeries 

5.3.3 Minimally Invasive Surgeries 

6. Geographical Analysis 

6.1 Introduction 

6.1.1 Regional Trends 

6.1.2 Impact Analysis 

6.1.3 Y-o-Y Growth Analysis 

6.1.3.1 By Geographical Area 

6.1.3.2 By Technology 

6.1.3.3 By Product 

6.1.3.4 By Type of Surgery 

6.1.4 Market Attractiveness Analysis 





6.1.5 Market Share Analysis 





6.2 North America 



6.3 Europe 


6.1.2 United States 

6.1.3 Canada 


6.2.2 U.K 

6.2.3 Spain 

6.2.4 Germany 

6.2.5 Italy 

6.2.6 France 

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6.4 Asia-Pacific 


6.3.2 China 

6.3.3 India 

6.3.4 Japan 

6.5 Latin America 


6.4.2 Brazil 

6.4.3 Argentina 

6.4.4 Mexico 

6.4.5 Rest of Latin America 

6.6 Middle East & Africa 


6.5.2 Middle-East 



6.5.3 Africa 

7.Strategic Analysis 

7.1 PESTLE analysis 

7.1.1 Political 

7.1.2 Economic 

7.1.3 Social 

7.1.4 Technological 

7.1.5 Legal 

7.1.6 Environmental 

7.2 Porter’s Five analysis 

7.2.1 Bargaining Power of Suppliers 

7.2.2 Bargaining Power of Consumers 

7.2.3 Threat of New Entrants 

7.2.4 Threat of Substitute Products and Services 

7.2.5 Competitive Rivalry within the Industry 

8.Market Leaders' Analysis 

8.1 Dow Chemical Co. 

8.1.1 Overview 

8.1.2 Product Analysis 

8.1.3 Financial analysis 

8.1.4 Recent Developments 

8.1.5 SWOT analysis 

8.1.6 Analyst View 

8.2 Bayer CropScience AG 

8.3 Syngenta International AG 

8.4 Chemtura Corp. 



8.5 Monsanto Co. 

8.6 Nufarm Ltd. 

8.7 Shijiazhuang Xingbai Bioengineering Co. 

8.8 BASF SE 

9.Competitive Landscape 

9.1 Market share analysis 

9.2 Merger and Acquisition Analysis 

9.3 Agreements, collaborations and Joint Ventures 

9.4 New Product Launches 

10.Market Outlook and Investment Opportunities 

Appendix 

a) List of Tables 

b) List of Figures 

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SCOPE OF THE REPORT 

 

 

 

 

Regional and country-level analysis and forecasts of the study market; providing 

Insights on the major countries/regions in which this industry is blooming and to also 

identify the regions that are still untapped 

Segment-level analysis in terms of technology, component, and type along with 

market size forecasts and estimations to detect key areas of industry growth in detail 

Identification of key drivers, restraints, opportunities, and challenges (DROC) in the 

market and their impact on shifting market dynamics 

Study of the effect of exogenous and endogenous factors that affect the global 

market; which includes broadly demographic, economics, and political, among other 

macro-environmental factors presented in an extensive PESTLE Analysis 



 

 

 

 

 

Study the micro environment factors that determine the overall profitability of an 

Industry, using Porter’s five forces analysis for analyzing the level of competition 

and business strategy development 

A comprehensive list of key market players along with their product portfolio, 

current strategic interests, key financial information, legal issues, SWOT analysis and 

analyst overview to study and sustain the market environment 

Competitive landscape analysis listing out the mergers, acquisitions, collaborations 

in the field along with new product launches, comparative financial studies and 

recent developments in the market by the major companies 

An executive summary, abridging the entire report in such a way that decisionmaking 

personnel can rapidly become acquainted with background information, 

concise analysis and main conclusions 

Expertly devised analyst overview along with Investment opportunities to provide 

both individuals and organizations a strong financial foothold in the market 


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