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Idiopathic Pulmonary Fibrosis (IPF) as the name suggests is a progressive disorder with no known aetiology. It is characterised by the thickening of the alveoli due to scarring resulting in cough. It is known to primarily occur in older adults over 60 years of age. The findings of IPF have a known association of Usual Interstitial Pneumonia (UIP) (Raghu et al., 2011; Kawano-Dourado & Kairalla, 2013; Wells, 2013). It has been deemed that the prognosis is generally poor when UIP has been confirmed (King et al., 2001b). The median survival rate of IPF is 50%, typically around two years after diagnosis (Raghu et al., 2011; King et al., 2001b).
Idiopathic Pulmonary Fibrosis (IPF) as the name suggests is a progressive disorder with no known aetiology. It is characterised by the thickening of the alveoli due to scarring resulting in cough. It is known to primarily occur in older adults over 60 years of age. The findings of IPF have a known association of Usual Interstitial Pneumonia (UIP) (Raghu et al., 2011; Kawano-Dourado & Kairalla, 2013; Wells, 2013). It has been deemed that the prognosis is generally poor when UIP has been confirmed (King et al., 2001b). The median survival rate of IPF is 50%, typically around two years after diagnosis (Raghu et al., 2011; King et al., 2001b).
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2 Huang et China Randomized<br />
al 8 Controlled<br />
Trial<br />
18-75 years 38 38 48 weeks Compared<br />
with<br />
placebo<br />
combined<br />
with highdose<br />
NAC,<br />
group, and aortic<br />
aneurysm,<br />
contusion,<br />
forearm fracture,<br />
and worsening<br />
IPF in the placebo<br />
group. However,<br />
the most common<br />
events were<br />
nasopharyngitis,<br />
cough and<br />
diarrhoea<br />
In the intervention<br />
group, the adverse<br />
event (AE) rate<br />
was higher than<br />
that in the control<br />
group. Rash was<br />
8 https://www.ncbi.nlm.nih.gov/pubmed/26496265<br />
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