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Idiopathic Pulmonary Fibrosis (IPF) as the name suggests is a progressive disorder with no known aetiology. It is characterised by the thickening of the alveoli due to scarring resulting in cough. It is known to primarily occur in older adults over 60 years of age. The findings of IPF have a known association of Usual Interstitial Pneumonia (UIP) (Raghu et al., 2011; Kawano-Dourado & Kairalla, 2013; Wells, 2013). It has been deemed that the prognosis is generally poor when UIP has been confirmed (King et al., 2001b). The median survival rate of IPF is 50%, typically around two years after diagnosis (Raghu et al., 2011; King et al., 2001b).

Idiopathic Pulmonary Fibrosis (IPF) as the name suggests is a progressive disorder with no known aetiology. It is characterised by the thickening of the alveoli due to scarring resulting in cough. It is known to primarily occur in older adults over 60 years of age. The findings of IPF have a known association of Usual Interstitial Pneumonia (UIP) (Raghu et al., 2011; Kawano-Dourado & Kairalla, 2013; Wells, 2013). It has been deemed that the prognosis is generally poor when UIP has been confirmed (King et al., 2001b). The median survival rate of IPF is 50%, typically around two years after diagnosis (Raghu et al., 2011; King et al., 2001b).

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interstitial pneumonia: the prognostic value of longitudinal functional trends. American<br />

journal of respiratory and critical care medicine. [Online]. 168 (5). pp. 531–7.<br />

Available from: http://www.ncbi.nlm.nih.gov/pubmed/12791580.<br />

Laupacis, A. (1997). Clinical Prediction Rules. The Journal of the American Medical<br />

Association. 277 (6). pp. 488–494.<br />

Lawson, W.E., Grant, S.W., Ambrosini, V., Womble, K.E., Dawson, E.P., Lane, K.B.,<br />

Markin, C., Renzoni, E., Lympany, P., Thomas, A.Q., Roldan, J., Scott, T.A., Blackwell,<br />

T.S., Phillips, J.A., Loyd, J.E. & du Bois, R.M. (2004). Genetic mutations in surfactant<br />

protein C are a rare cause of sporadic cases of IPF. Thorax. [Online]. 59 (11). pp. 977–<br />

80. Available from: http://www.ncbi.nlm.nih.gov/pubmed/15516475.<br />

Le, A. V, Cho, J.Y., Miller, M., McElwain, S., Golgotiu, K. & Broide, D.H. (2007).<br />

Inhibition of allergen-induced airway remodeling in Smad 3-deficient mice. Journal of<br />

immunology (Baltimore, Md. : 1950). 178 (11). pp. 7310–7316.<br />

Leandro, G. (2004). Meta-analysis in medical research: the handbook for the understanding<br />

and practice of meta-analysis. Oxford: Blackwell.<br />

Lederer, D.J., Arcasoy, S.M., Barr, R.G., Wilt, J.S., Bagiella, E., D’Ovidio, F., Sonett, J.R. &<br />

Kawut, S.M. (2006a). Racial and ethnic disparities in idiopathic pulmonary fibrosis: A<br />

UNOS/OPTN database analysis. American journal of transplantation : official journal<br />

of the American Society of Transplantation and the American Society of Transplant<br />

Surgeons. 6 (10). pp. 2436–42.<br />

Lederer, D.J., Arcasoy, S.M., Wilt, J.S., D’Ovidio, F., Sonett, J.R. & Kawut, S.M. (2006b).<br />

Six-minute-walk distance predicts waiting list survival in idiopathic pulmonary fibrosis.<br />

American journal of respiratory and critical care medicine. [Online]. 174 (6). pp. 659–<br />

64. Available from: http://www.ncbi.nlm.nih.gov/pubmed/16778159.<br />

Lederer, D.J., Caplan-Shaw, C.E., O’Shea, M.K., Wilt, J.S., Basner, R.C., Bartels, M.N.,<br />

Sonett, J.R., Arcasoy, S.M. & Kawut, S.M. (2006c). Racial and ethnic disparities in<br />

survival in lung transplant candidates with idiopathic pulmonary fibrosis. American<br />

journal of transplantation : official journal of the American Society of Transplantation<br />

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