Systematic-Review-Drug-Efficiency-Dissertation-Sample-Work-Tutors-India
Idiopathic Pulmonary Fibrosis (IPF) as the name suggests is a progressive disorder with no known aetiology. It is characterised by the thickening of the alveoli due to scarring resulting in cough. It is known to primarily occur in older adults over 60 years of age. The findings of IPF have a known association of Usual Interstitial Pneumonia (UIP) (Raghu et al., 2011; Kawano-Dourado & Kairalla, 2013; Wells, 2013). It has been deemed that the prognosis is generally poor when UIP has been confirmed (King et al., 2001b). The median survival rate of IPF is 50%, typically around two years after diagnosis (Raghu et al., 2011; King et al., 2001b).
Idiopathic Pulmonary Fibrosis (IPF) as the name suggests is a progressive disorder with no known aetiology. It is characterised by the thickening of the alveoli due to scarring resulting in cough. It is known to primarily occur in older adults over 60 years of age. The findings of IPF have a known association of Usual Interstitial Pneumonia (UIP) (Raghu et al., 2011; Kawano-Dourado & Kairalla, 2013; Wells, 2013). It has been deemed that the prognosis is generally poor when UIP has been confirmed (King et al., 2001b). The median survival rate of IPF is 50%, typically around two years after diagnosis (Raghu et al., 2011; King et al., 2001b).
You also want an ePaper? Increase the reach of your titles
YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.
313–9. Available from: http://www.ncbi.nlm.nih.gov/pubmed/9087875.<br />
Kakugawa, T., Mukae, H., Hayashi, T., Ishii, H., Abe, K., Fujii, T., Oku, H., Miyazaki, M.,<br />
Kadota, J. & Kohno, S. (2004). Pirfenidone attenuates expression of HSP47 in murine<br />
bleomycin-induced pulmonary fibrosis. The European respiratory journal. [Online]. 24<br />
(1). pp. 57–65. Available from: http://www.ncbi.nlm.nih.gov/pubmed/15293605.<br />
Kang, H.-R., Cho, S.J., Lee, C.G., Homer, R.J. & Elias, J.A. (2007). Transforming growth<br />
factor (TGF)-beta1 stimulates pulmonary fibrosis and inflammation via a Bax-dependent,<br />
bid-activated pathway that involves matrix metalloproteinase-12. The Journal of<br />
biological chemistry. 282 (10). pp. 7723–7732.<br />
Karimi-Shah, B.A. & Chowdhury, B.A. (2015). Forced Vital Capacity in Idiopathic<br />
Pulmonary Fibrosis — FDA <strong>Review</strong> of Pirfenidone and Nintedanib. New England<br />
Journal of Medicine. [Online]. 372 (13). pp. 1189–1191. Available from:<br />
http://www.nejm.org/doi/abs/10.1056/NEJMp1500526.<br />
Katzenstein, A.L. & Myers, J.L. (2000). Nonspecific interstitial pneumonia and the other<br />
idiopathic interstitial pneumonias: classification and diagnostic criteria. The American<br />
journal of surgical pathology. [Online]. 24 (1). pp. 1–3. Available from:<br />
http://www.ncbi.nlm.nih.gov/pubmed/10632482.<br />
Kawano-Dourado, L. & Kairalla, R.A. (2013). Pneumonia intersticial usual: um padrão ou<br />
uma doença? Reflexão sobre o assunto. Jornal Brasileiro de Pneumologia. [Online]. 39<br />
(1). pp. 111–112. Available from:<br />
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-<br />
37132013000100017&lng=pt&nrm=iso&tlng=en.<br />
Kelly, B.G., Lok, S.S., Hasleton, P.S., Egan, J.J. & Stewart, J.P. (2002). A Rearranged Form<br />
of Epstein–Barr Virus DNA Is Associated with Idiopathic Pulmonary Fibrosis.<br />
American Journal of Respiratory and Critical Care Medicine. [Online]. 166 (4). pp.<br />
510–513. Available from: http://www.atsjournals.org/doi/abs/10.1164/rccm.2103058.<br />
Keogh, B. & Crystal, m R. (1980). Pulmonary function testing in interstitial pulmonary<br />
disease. What does it tell us? Chest. 78 (6). pp. 856–865.<br />
© 2017-2018 All Rights Reserved, No part of this document should be modified/used without prior consent<br />
<strong>Tutors</strong> <strong>India</strong> - Your trusted mentor since 2001<br />
www.tutorindia.com I UK # +44-1143520021, info@tutorsindia.com<br />
Page 135 of 172
Change language