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Idiopathic Pulmonary Fibrosis (IPF) as the name suggests is a progressive disorder with no known aetiology. It is characterised by the thickening of the alveoli due to scarring resulting in cough. It is known to primarily occur in older adults over 60 years of age. The findings of IPF have a known association of Usual Interstitial Pneumonia (UIP) (Raghu et al., 2011; Kawano-Dourado & Kairalla, 2013; Wells, 2013). It has been deemed that the prognosis is generally poor when UIP has been confirmed (King et al., 2001b). The median survival rate of IPF is 50%, typically around two years after diagnosis (Raghu et al., 2011; King et al., 2001b).

Idiopathic Pulmonary Fibrosis (IPF) as the name suggests is a progressive disorder with no known aetiology. It is characterised by the thickening of the alveoli due to scarring resulting in cough. It is known to primarily occur in older adults over 60 years of age. The findings of IPF have a known association of Usual Interstitial Pneumonia (UIP) (Raghu et al., 2011; Kawano-Dourado & Kairalla, 2013; Wells, 2013). It has been deemed that the prognosis is generally poor when UIP has been confirmed (King et al., 2001b). The median survival rate of IPF is 50%, typically around two years after diagnosis (Raghu et al., 2011; King et al., 2001b).

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1.9 Chapterisation<br />

Chapter 1- Introduction: This chapter discusses the background of the study followed by the<br />

problem statement. From the problem statement, the research aims and objectives of the<br />

study are stated. This chapter also includes the scope, significance and chapter scheme of the<br />

dissertation.<br />

Chapter 2- <strong>Review</strong> of Literature: The review of literature begins with the concepts and<br />

definition of IPF along with the signs, symptoms, clinical presentation, pathogenesis,<br />

diagnosis and management of the disease. The current modes of management along with<br />

previous literature are discussed. The research gap is then extracted and debriefed.<br />

Chapter 3- Materials and Methods: The chapter includes the search strategy, inclusion and<br />

exclusion criteria and the methods of analysis for the extracted data. A quality assessment of<br />

the included studies is also included here.<br />

Chapter 4- Results and Discussion: The results contain a review of the selected studies along<br />

with the statistical analysis of the extracted data. Besides this a critical review of all the<br />

papers coupled with the implications of the findings of the study is discussed.<br />

Chapter 5- Summary, Conclusion, Contribution to Knowledge, Suggestion for Future<br />

Research: The chapter contains the findings of the study in brief. It also explains how the<br />

findings relate to achieving the objectives of the study.<br />

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