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Idiopathic Pulmonary Fibrosis (IPF) as the name suggests is a progressive disorder with no known aetiology. It is characterised by the thickening of the alveoli due to scarring resulting in cough. It is known to primarily occur in older adults over 60 years of age. The findings of IPF have a known association of Usual Interstitial Pneumonia (UIP) (Raghu et al., 2011; Kawano-Dourado & Kairalla, 2013; Wells, 2013). It has been deemed that the prognosis is generally poor when UIP has been confirmed (King et al., 2001b). The median survival rate of IPF is 50%, typically around two years after diagnosis (Raghu et al., 2011; King et al., 2001b).

Idiopathic Pulmonary Fibrosis (IPF) as the name suggests is a progressive disorder with no known aetiology. It is characterised by the thickening of the alveoli due to scarring resulting in cough. It is known to primarily occur in older adults over 60 years of age. The findings of IPF have a known association of Usual Interstitial Pneumonia (UIP) (Raghu et al., 2011; Kawano-Dourado & Kairalla, 2013; Wells, 2013). It has been deemed that the prognosis is generally poor when UIP has been confirmed (King et al., 2001b). The median survival rate of IPF is 50%, typically around two years after diagnosis (Raghu et al., 2011; King et al., 2001b).

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References<br />

Abehsera, M., Valeyre, D., Grenier, P., Jaillet, H., Battesti, J.P. & Brauner, M.W. (2000).<br />

Sarcoidosis with pulmonary fibrosis: CT patterns and correlation with pulmonary<br />

function. AJR. American journal of roentgenology. 174 (6). pp. 1751–1757.<br />

Abid, S.H., Malhotra, V. & Perry, M.C. (2001). Radiation-induced and chemotherapyinduced<br />

pulmonary injury. Current opinion in oncology. 13 (4). pp. 242–248.<br />

Adamson, I.Y. & Bowden, D.H. (1974). The pathogenesis of bleomycin-induced pulmonary<br />

fibrosis in mice. The American journal of pathology. 77 (2). pp. 185–197.<br />

Ahluwalia, N., Shea, B.S. & Tager, A.M. (2014). New therapeutic targets in idiopathic<br />

pulmonary fibrosis. Aiming to rein in runaway wound-healing responses. American<br />

journal of respiratory and critical care medicine. [Online]. 190 (8). pp. 867–78.<br />

Available from: http://www.ncbi.nlm.nih.gov/pubmed/25090037.<br />

Akagi, T., Matsumoto, T., Harada, T., Tanaka, M., Kuraki, T., Fujita, M. & Watanabe, K.<br />

(2009). Coexistent emphysema delays the decrease of vital capacity in idiopathic<br />

pulmonary fibrosis. Respiratory medicine. [Online]. 103 (8). pp. 1209–15. Available<br />

from: http://www.ncbi.nlm.nih.gov/pubmed/19251407.<br />

Alakhras, M., Decker, P.A., Nadrous, H.F., Collazo-Clavell, M. & Ryu, J.H. (2007). Body<br />

mass index and mortality in patients with idiopathic pulmonary fibrosis. Chest. [Online].<br />

131 (5). pp. 1448–53. Available from: http://www.ncbi.nlm.nih.gov/pubmed/17400656.<br />

Alder, J.K., Chen, J.J.-L., Lancaster, L., Danoff, S., Su, S. -c., Cogan, J.D., Vulto, I., Xie, M.,<br />

Qi, X., Tuder, R.M., Phillips, J.A., Lansdorp, P.M., Loyd, J.E. & Armanios, M.Y.<br />

(2008). Short telomeres are a risk factor for idiopathic pulmonary fibrosis. Proceedings<br />

of the National Academy of Sciences. [Online]. 105 (35). pp. 13051–13056. Available<br />

from: http://www.pnas.org/cgi/doi/10.1073/pnas.0804280105.<br />

Allahverdian, S., Harada, N., Singhera, G.K., Knight, D.A. & Dorscheid, D.R. (2008).<br />

Secretion of IL-13 by airway epithelial cells enhances epithelial repair via HB-EGF.<br />

American journal of respiratory cell and molecular biology. 38 (2). pp. 153–160.<br />

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