22.11.2018 Views

Systematic-Review-Drug-Efficiency-Dissertation-Sample-Work-Tutors-India

Idiopathic Pulmonary Fibrosis (IPF) as the name suggests is a progressive disorder with no known aetiology. It is characterised by the thickening of the alveoli due to scarring resulting in cough. It is known to primarily occur in older adults over 60 years of age. The findings of IPF have a known association of Usual Interstitial Pneumonia (UIP) (Raghu et al., 2011; Kawano-Dourado & Kairalla, 2013; Wells, 2013). It has been deemed that the prognosis is generally poor when UIP has been confirmed (King et al., 2001b). The median survival rate of IPF is 50%, typically around two years after diagnosis (Raghu et al., 2011; King et al., 2001b).

Idiopathic Pulmonary Fibrosis (IPF) as the name suggests is a progressive disorder with no known aetiology. It is characterised by the thickening of the alveoli due to scarring resulting in cough. It is known to primarily occur in older adults over 60 years of age. The findings of IPF have a known association of Usual Interstitial Pneumonia (UIP) (Raghu et al., 2011; Kawano-Dourado & Kairalla, 2013; Wells, 2013). It has been deemed that the prognosis is generally poor when UIP has been confirmed (King et al., 2001b). The median survival rate of IPF is 50%, typically around two years after diagnosis (Raghu et al., 2011; King et al., 2001b).

SHOW MORE
SHOW LESS

Create successful ePaper yourself

Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.

6 min walk<br />

the distinct possibility<br />

distance;<br />

that the combination<br />

- Primary<br />

might be harmful in<br />

endpoint: 28<br />

patients with IPF<br />

days after last<br />

drug dose<br />

2<br />

Huang et<br />

al 23 76 33 5 38 0<br />

52.63 per cent<br />

high in<br />

- - The primary<br />

endpoints<br />

PFD combined with<br />

highdose NAC<br />

Intervention<br />

were defined<br />

compared to placebo<br />

than in control<br />

as the change<br />

combined with high-<br />

grou<br />

in FVC from<br />

dose NAC prolonged<br />

baseline to<br />

the Progression Free<br />

week 48, and<br />

Survival time in<br />

the change in<br />

Chinese IPF patients<br />

the maximal<br />

with mild to moderate<br />

distance on<br />

impairment of<br />

the 6MWT<br />

pulmonary function<br />

and the<br />

23 https://www.ncbi.nlm.nih.gov/pubmed/26496265<br />

© 2017-2018 All Rights Reserved, No part of this document should be modified/used without prior consent<br />

<strong>Tutors</strong> <strong>India</strong> - Your trusted mentor since 2001<br />

www.tutorindia.com I UK # +44-1143520021, info@tutorsindia.com<br />

Page 90 of 172

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!