Broschüre SP Scientific Benchtop Pro

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BenchTop Pro with Omnitronics 

The VirTis BenchTop Pro freeze dryers have 

been designed to meet the needs of the most 

demanding research laboratories. Each 

system can be configured to accommodate 

present and future requirements. Condenser 

refrigeration packages of -55°C, -75°C, 

-85°C and -105°C can meet the demands 

of both aqueous or aqueous-solvent based 

formulations. 

You can configure your system 

to run just a few samples or 

to process a relatively heavy 

load with condenser size 

choices of 3 liter, 8 liter or 

9 liter. Selecting a size and 

temperature configuration 

allows you to maximize the use 

of the freeze dryer in your lab 

while not paying needlessly 

for unnecessary capacity or 

refrigeration. 

Each system can be 

configured to meet 

the needs of the most 

demanding research 

laboratories. 

02

Manifolds 

Manifolds are available in a variety 

of styles and are designed to be 

interchangeable. There are a number of 

considerations when selecting a manifold. 

In a multi-user lab it is often best to utilize 

a robust stainless steel manifold. In 

applications where inorganic solvents are 

being utilized or you are rack drying and 

want to ensure visibility an acrylic manifold 

would be preferred. In applications 

with organic solvents the stainless steel 

manifolds will provide long lasting use. 

03

Omnitronics Controller 

The Omnitronics Controller simplifies freeze drying 

and makes the system easy to operate. One touch 

start up and shut down ensure that your product 

and freeze dryer are protected from inappropriate 

procedures. The graphic display provides at-aglance 

understanding of the status of the freeze 

dryer and whether or not appropriate freeze drying 

conditions exist. Audible alarms help notify the 

user of potential problems with the system and 

hence, with the product. All Omnitronics controllers 

come complete with a trending screen that allows 

you to watch critical parameters on an on-going 

basis if required. Utilizing the optional Ethernet 

control, you can connect the freeze dryer to your 

company’s or institution’s network, and monitor 

and/or control your freeze dryer from any other 

location on the network. The Ethernet option 

also allows print out in a batch record, alphanumeric, 

type report. 

One touch start up and shut 

down ensure that your product 

and freeze dryer are protected 

from inappropriate procedures. 

04

Don’t waste time with 

slow & messy defrosting 

The hot gas defrost in the BenchTop Pro 

allows for fast turnaround time and helps 

minimize clean up efforts when having 

to pour warm water into a condenser. In 

addition, corrosive solvents which are more 

active at ambient and higher temperatures 

will spend a minimum amount of dwell time 

in the condenser with fast hot gas defrost— 

no need to wait overnight to drain the 

system. 

05

VirTis/SP Scientific supports your freeze drying endeavors with a team of technically 

qualified associates who can help you choose the right system and provide you with 

helpful application tips. In addition, SP Scientific provides the globally recognized 

LyoLearn Webinar series. These are free webinars, provided by industry experts on topics 

of interest to the freeze drying community. Our technical papers and application notes 

can be downloaded from our website at your convenience and are designed to help you 

get the most out of your freeze dryer. 

Standard Omnitronics 

• High performance PLC controller 

• Easy to use interface provided by full color 

touch screen navigation. 

• Ensure a longer lifetime for your freeze dryer 

by avoiding utility degradation conditions 

such as high ambient and low voltage with 

alert notifications 

• Real time graphical screen data logging to 

review system parameters during a run 

• Help protect your product from unfavorable 

conditions with “out of range” and “in 

range” for freeze drying indicators 

• Save time with one button start-up and one 

button shut-down 

• Stores years of data on micro memory card 

• Set point control with automatic PID tuning 

• Precise alpha-numeric display of setting and 

read-out temperatures 

• Currently available in English, Spanish, 

German & French. Other languages may be 

available on request. 

• User selectable pressure in millibars, millitor 

or pascals. Temperature in °C or °F 

Omnitronics with 

Ethernet Option 

• Control and/or monitor your system from 

anywhere on your network 

• Enable the freeze dryer to email you if 

there is a process alert/alarm 

• Full reporting capabilities with batch 

reports that can be exported to Windows 

Excel® 

• Optional remote service support by 

allowing our qualified technicians to 

access your system 

06

Features of the BenchTop Pro 

• Condensers of 3, 8 and 9 liters in a bench top 

footprint 

• Refrigeration packages for maximum low 

temperature of -55°, -75°, -85° or -105°C 

• One touch start-up and shut-down 

• Pressure control to avoid back-streaming or for 

faster freeze drying 

• A variety of manifolds to accommodate most 

processing configurations 

• Rugged and reliable Pirani vacuum sensor 

• Hot gas defrost in approximately 10 minutes or 

less 

• Optional vacuum pump isolation valve 

Selection Guide 

There are two main criteria for selecting the benchtop freeze dryer that is right for 

you. The first is determining what condenser capacity you need in between defrost 

cycles. The second is to determine what solvents you may be using in your process. 

When utilizing water as the only solvent the highest condenser temperature offered is 

appropriate. In cases where organic or inorganic solvents are being utilized as part 

of the solvent matrix the lowest temperature condenser is always preferred. 

Load Capacity 

Solvents 3 Liter 8 Liter 9 Liter 

Water ES (-55°C) XL (-75°C) ES (-55°C) 

Water and inorganic solvents XL (-75°C) ZL (-105°C) EL (-85°C) 

Water & organic solvents XL (-75°C) ZL (-105°C) EL (-85°C) 

Manifold Material Choice 

Acrylic or stainless steel. Multiple user labs may 

have better experience with stainless steel. 

Maximize use of acrylic and minimize use of 

stainless steel. 

Maximize use of stainless steel and minimize 

use of acrylic if possible. 

Vacuum Pump 

Considerations 

Standard oil sealed, rotary vane direct 

drive pump. When working in low 

pressure conditions consider a dry scroll 

pump if oil backstreaming is a concern. 

Standard pump with corrosion resistant 

oil or combination standard pump with 

diaphragm pump. 

Standard pump with corrosion resistant 

oil or combination standard pump with 

diaphragm pump. 

Water & both organic and inorganic 

solvents 

XL (-75°C) ZL (-105°C) EL (-85°C) 

Maximize use of acrylic if higher in organic 

solvents. Maximize use of stainless steel if 

higher in organic solvents. 

Combination standard pump with 

diagphragm pump. 

07

BenchTop Pro with 

Omnitronics 

3L Freeze Dryer 

The BenchTop Pro with Omnitronics 

3 Liter system is designed as 

a personal freeze dryer or for 

small laboratories processing less 

product at any one time. This unit 

is available with all of the manifold 

choices that can be used on the 

larger benchtop system giving it the 

same flexibility and performance. 

• Condenser temperature option of 

-55°C (-52°C for 50Hz) or -75°C 

(-72°C for 50Hz) 

• CFC free refrigerants 

• Overall condenser capacity of 3 

liters 

• Approximate 24 hour rating of 2 

liters/24 hour (extreme pressure 

and temperature, water only)* 

• Omnitronics Control for monitoring 

critical freeze drying parameters 

and for vacuum control 

• Remote control, batch reporting 

and emailed alarms with Ethernet 

interface 

• Fast turnaround time with hot gas 

defrost and smooth condenser walls 

• Alarms for out-of-range conditions 

*The 24 hour rating is not reproducible 

in the lab with product. This rating is to 

illustrate the efficiency of the refrigeration 

design from one system to another. It is 

based on loading as much water onto the 

freeze dryer in 24 hours as possible with 

equipment not typically used in freeze 

drying applications 

08 

BenchTop Pro with Omnitronics 3 Liter Freeze Dryer 

Condenser blank off (no load) 

temperature 

Condenser capacity in 24 hours 

(water, heaviest load) 

Overall condenser capacity 

Omnitronics control 

* Vacuum indication in millitor, 

microbar or pascals (user selectable) 

* Temperature indication in °C or °F 

(user selectable) 

* Voltage and ambient temperature 

indicators 

ES -55°C (-52°C for 50Hz) / XL -75°C 

(-72°C for 50Hz) 

Approximately 2 Liters 

3 Liters 

Atmospheric to 1 mT 

"T" type thermocouples 

Alarms if out of acceptable range for 

system 

* Communication ports Ethernet connection 

Defrost Method 

System refrigerant 

Condenser type 

Compressor(s) 

Average time for pull down to 100 mT 

Ultimate system vacuum with manifold 

Base cabinet dimensions W x D x H 

Weight 

(unpackaged and without manifold) 

Hot gas 

CFC free 

Smooth wall interior with bottom external 

coil 

ES is 1/3 HP, XL is 3/8 HP 

15 minutes 

20 mT 

15.5in x 28.5in x 17in (39.4cm x 

72.4cm x 43.2cm) 

60 lbs (27.3 kg) 

Standard Voltages 100-120V 50/60Hz, 200-240V 

50Hz/208-230V 60Hz 

Manifold and Vacuum Pumps Sold Separately 

- See Accessories 

Current as of May 2013; Specifications are subject to change


Omnitronics 

8L Freeze Dryer 


8 liter is designed for heavier loads 

and for use with solvents other than 

water. It is available with a -75°C 

or -105°C condenser. The -105°C 

option is preferred for applications 

involving low freezing point solvents 

such as TFA, acetronitrile and 

alcohols. Even if the freezing point 

of your solvent is below -105°C this 

temperature condenser is more likely 

to liquefy the solvent and thus prevent 

it from migrating easily to the vacuum 

pump. 

• Offered in low and ultra-low condenser 

configuration -75°C (-72°C for 50Hz) 

or -105°C (-102°C for 50Hz) 


• Condenser capacity total of 8 liters 


liters/24 hours (extreme pressure and 

temperature, water only)* 


critical freeze drying parameters and 

for vacuum control 

• Remote control, batch reporting and 

emailed alarms with Ethernet interface 

• Fast turn around with hot gas defrost. 

• Alarms for out-of range-conditions 

*The 24 hour rating is not reproducible in the 

lab with product. This rating is to illustrate 

the efficiency of the refrigeration design 

from one system to another. It is based on 

loading as much water onto the freeze dryer 

in 24 hours as possible with equipment not 

typically used in freeze drying applications 



temperature 

Condenser capacity in 24 hours 

(water, heaviest load) 



* Vacuum indication in millitor, microbar 

or pascals (user selectable) 




indicators 

XL -75°C (-72°C for 50Hz) /ZL 

-105°C (-102°C for 50Hz) 


8 Liters 




system 





Hot gas 

CFC free 

Smooth wall interior with bottom 

external coil 

Compressor(s) XL is 3/8 HP, ZL is 1/3 HP and 3/8 

HP 




Weight 


18 minutes 

20 mT 

15.5in x 28.5in x 17in (39.4cm x 

72.4cm x 43.2cm) 

131 lbs (59.4 kg) 


50Hz/208-230V 60Hz 



Current as of May 2013; Specifications are subject to change 

09


Omnitronics 

9 Liter 


9 liter is the high capacity 

workhorse of the bench top freeze 

dryer product family. Built for labs 

that require greater throughput and 

freeze drying availability, for some 

labs it will handle their weekly 

requirements without shut down 

and defrost. It is available with a 

-55°C or -85°C condenser 

• Offered in low and ultra-low 

condenser configuration -55°C 

(-52°C for 50Hz) or -85°C (-85°C 

for 50Hz) 


• Condenser capacity total of 9 liters 


liters/24 hours (extreme pressure 

and temperature, water only)* 


critical freeze drying parameters 

and for vacuum control 

• Remote control, batch reporting 

and emailed alarms with Ethernet 

interface 

• Fast turn around with hot gas 

defrost. 

• Alarms for out-of range-conditions 

*The 24 hour rating is not reproducible 

in the lab with product. This rating is to 

illustrate the efficiency of the refrigeration 

design from one system to another. It is 

based on loading as much water onto the 

freeze dryer in 24 hours as possible with 

equipment not typically used in freeze 

drying applications 

10 



temperature 

Condenser capacity in 24 hours (water, 

heaviest load) 



* Vacuum indication in millitor, microbar 

or pascals (user selectable) 




indicators 

ES -55°C (-52°C for 50Hz) /EL -85°C 

(-82°C for 50Hz) 


9 Liters 




system 





Hot gas 

CFC free 

Internal Coil 

Compressor(s) ES is 1/3 HP, EL is 1/3 HP and 3/8 

HP 




Weight (lb/kg) 


18 minutes 

20 mT 

15.5in x 28.5in x 17in (39.4cm x 

72.4cm x 43.2cm) 

131 lbs (59.4 kg) 


50Hz/208-230V 60Hz 



Current as of May 2013; Specifications are subject to change

Accessories for the BenchTop Pro 

Tree or “T” type Manifolds 

Available in 8 or 12 port configuration. 316 Stainless steel complete with Quick 

Seal Valves and built in adaptor plate. 

Part Number Description Dimensions 

BTP-MST-08 Stainless steel manifold, 8 

ports 

BTP-MST-12 Stainless steel manifold, 12 

ports 

HEIGHT 19.25” (48.9 CM), 

LENGTH 15” (38.1 CM), WIDTH 

15.25” (38.74 CM) 

HEIGHT 19.25” (48.9 CM), 


23” (58.42 CM) 

Condensate Drip Pan Kit for Tree of “T” Type Manifolds 

This condensate drip pan kit will provide support for flasks on the Tree manifold 

and also collect condensate as it drips off the outside of the product containers 

during freeze drying. 

Part Number 

CPK 

Description 

Stainless steel flask support with plastic trays 

Condensate Drip Pan Kit for Tree of “T” Type Manifolds 

This condensate drip pan kit will provide support for flasks on the Tree 

manifold and also collect condensate as it drips off the outside of the product 

containers during freeze drying. 

Part Number 

CPK 

Description 

Stainless steel flask support 

with plastic trays 

Vertical Manifold 

Available in 12 port configuration. 316 stainless steel complete with Quick Seal 

Valves and built in adaptor plate. 


BTP-MSV-12 Stainless steel manifold, 12 

ports 

HEIGHT 16.25” (41.28 CM), 


15” (38.1 CM) 

Part Number 

CPK 

Description 

Stainless steel flask support with plastic trays 

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Drum Manifolds 

Classic drum type manifolds are available in both stainless steel and acrylic 

configuration. Comes complete with condenser adaptor plate of same material. 

Accessory racks can be coupled with these manifolds for rack drying—either heated or 

unheated. 


BTP-DA-08-0 8 port acrylic drum manifold DRUM - HEIGHT 12.25” (31.12 CM) ID 14.25” 

(36.2 CM) OD, WIDTH Ø9” (22.86 CM) ID, 

Ø9.5” (24.13 CM) OD 

ADAPTER PLATE – HEIGHT 1” (2.54 CM), 

WIDTH Ø15” (38.1 CM) 

OVERALL ASSEMBLY – HEIGHT 15” (38.1 CM), 

WIDTH Ø18” (45.72 CM) WITH QUICK SEAL 

VALVES INSTALLED 

BTP-DA-12-0 12 port acrylic drum manifold DRUM – HEIGHT 16.25” (41.28 CM) ID, 18” 

(45.72 CM) OD, WIDTH Ø11.5” (29.21 CM) 

ID, Ø 12” (30.48 CM) OD 

ADAPTER PLATE – HEIGHT 1” (2.54 CM), 

WIDTH Ø15” (38.1 CM), 

OVERALL ASSEMBLY – HEIGHT 18.75”, WIDTH 

Ø20.5” (52.07 CM) WITH QUICK SEAL VALVES 

INSTALLED 

BTP-DA-12-H 

BTP-DS-18-0 

12 port acrylic drum manifold 

for use with heated racks 

18 port stainless steel drum 

manifold 

DRUM - HEIGHT 16.25” (41.28 CM) ID, 18” 

(45.72 CM) OD, WIDTH Ø11.5” (29.21 CM) 

ID, Ø12” (30.48 CM) OD 

ADAPTER PLATE - HEIGHT 1.5” (3.81 CM), 

WIDTH Ø15” (38.1 CM) 

OVERALL ASSEMBLY – HEIGHT 19.25”, WIDTH 

Ø20.5” (52.07) WITH QUICK SEAL VALVES 

INSTALLED 

DRUM - HEIGHT 13” (33.02 CM) ID, 13.25” 

(33.66 CM) OD, WIDTH Ø12” (30.48 CM) ID, 

Ø13” (33.02 CM) OD 

SST ADAPTER PLATE – HEIGHT 0.25” (0.64 

CM), WIDTH Ø15” (38.1 CM) 

ACRYLIC COVER – HEIGHT 0.75” (1.91 CM), 

WIDTH Ø13.5” (34.29) 

OVERALL ASSEMBLY – HEIGHT 14.25” (36.2 

CM), WIDTH Ø21” (Ø53.34 CM) WITH QUICK 

SEAL VALVES INSTALLED 

Drum Manifold Racks 

Racks are constructed of 304 stainless steel and adjustable. 


BR-3U-08 3 tiered rack for BTP-DA-08 HEIGHT 10.5” (26.67 CM), WIDTH Ø8.5 

(21.59 CM), SPACING 3.50” (8.89 CM) 

BR-3U-12 3 tiered rack for BTP-DA-12 HEIGHT 14.5” (36.83 CM), WIDTH Ø10.5 


BR-3U-18 3 tiered rack for BTP-DA-18 HEIGHT 12” (30.48 CM), WIDTH Ø10.5 


BR-3H-13 

3 tiered rack for BTP-DA-12 with 

on off heater 

HEIGHT 12” (30.48 CM), WIDTH Ø8.5 (21.59 

CM), SPACING 4.75” (12.07 CM) 

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Wide Mouth Filter Seal Flasks 

These borosilicate flasks are specially designed for manifold freeze drying. The flat 

bottom makes it easy to stabilize the flask in its upright position for “plug” or static 

freezing. The wide mouth of the flask makes it easier to place product in the flask and 

perhaps even more importantly, remove product from the flask. The snap on silicone top 

ensures a good vacuum seal and comes complete with a filter to eliminate the possibility 

of cross contamination when several flasks are on the same dryer. All components can 

be autoclaved. The flask itself is available in regular and in safety coated configurations. 

Must be used with manifold adaptors. 

Regular Flask 

Part Number 

Safety Coated 

Part Number 

Maximum 

Capacity 

Maximum 

Fill 

235390 312892 40 ml 20 ml 

235382 312900 75 ml 35 ml 

118174 312918 150 ml 75 ml 

118208 312918 300 ml 150 ml 

118232 312934 600 ml 300 ml 

118273 312942 1200 ml 600 ml 

118307 312959 2000 ml 1000 ml 

Manifold Adaptors 

Part Number Material Shape Port Size Compatible 

Flasks 

367424 Plastic Straight Barb ¾” 150 – 2000 ml 

179655 Glass Straight ¾” 150 – 2000 ml 

177923 Stainless steel Straight ¾” 150 – 2000 ml 

177899 Glass 45 degree ¾” 150 – 2000 ml 

177931 Stainless steel 45 degree ¾” 150 – 2000 ml 

179622 Glass Straight ¾” 40 & 75 ml 

177873 Glass 45 degree ¾” 40 & 75 ml 

Don’t see the adaptor you need? Please inquire. 

13

Ampule Adaptor 

Designed to hold 19 ampule type containers on a single valve 

Part Number 

Description 

413534 19 port ampule adaptor 

We also carry a full line of sealing torches and ampules. Please inquire. 

Container System 

Two container systems are offered. One for bulk and one for stoppering 

applications. Containers are made of 304 SS and are attached to your 

manifold with vacuum tubing for processing in bulk or in vials. 


438032 Bulk ss container 

SC-1 Small stoppering container 7 – 5 ml vials, 5 – 10 ml vials, 

4 – 30 ml vials, 1 – 100 ml vial 

Vacuum Pumps 

VirTis/SP Scientific is pleased to offer a full line of vacuum pumps to solve 

any application need. Included in our offering are the standard two stage, 

oil sealed rotary direct drive vacuum pumps as well as dry scroll type 

pumps and combination pumps that are joining of the standard pump with 

a diaphragm pump for service in highly corrosive environments. 

Vacuum 

Foreline Traps 

These traps are designed to 

help prevent the migration of 

contaminants to the vacuum 

pump or to minimize vacuum 

pump oil back-streaming. 

They are placed in the 

vacuum line between the 

freeze dryer and the vacuum 

pump. 

Part Number 

FTA 

FTA-SS 

FTA-AC 

FTA-MS 

Description 

Filter trap housing, insert 

purchased separately 

Soda sorb insert for acid applications 

Activated charcoal insert for organic solvent applications 

Molecular sieve insert for water vapor and to help 

minimize oil backstreaming 

14

SP Scientific Supports You in Ways Unrivaled in the Industry: 

LyoLearn Webinars: 

Free online seminar series featuring topics of interest to lyophilization scientists and 

presented by industry experts. Live sessions allow participants to interact with renowned 

freeze-drying specialists, such as Dr. John Carpenter, Dr. Steve Nail, Dr. Michael Pikal, 

and other who’s who of the freeze drying community. Each online LyoLearn Session is 

recorded and archived for future viewing. 

Hands-On Training: 

SP Scientific’s hands-on training courses offer attendees the chance to optimize their 

learning experiences by using tangible applications in a controlled setting. Led by “go-to” 

leaders in the lyophilization industry, these courses are a must for anyone getting started 

in freeze drying or scientists looking for collaborative environment to share best practices, 

ideas and theories. 

Technical Briefs: 

SP Scientific’s technical briefs are relevant papers covering in-demand topics. Available 

in a variety of languages, titles include: The Relevance of Product Resistance in Primary 

Drying, The Importance of Controlling Nucleation Temperature During the Freeze Step, 

Case Studies in Diagnosing and Correcting Problematic Lyophilization Cycles and/or 

Formulations, Basic Principles of Freeze Drying, and Basic Lyophilizer Maintenance Helps 

to Assure Good Results. 

All of this is available on our website 

www.SPScientific.com. 

Logon to learn more! 

03

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Broschüre SP Scientific Benchtop Pro

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