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Program & Abstract Book - EPFL Latsis Symposium 2009

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<strong>EPFL</strong> <strong>Latsis</strong> <strong>Symposium</strong> <strong>2009</strong>: Understanding Violence<br />

P-29<br />

th e p s y c h o p a t h o l o g y o f r e p e a t e D<br />

a g g r e s s i o n: an e X p e r i m e n t a l s t u D y<br />

Kudryavtseva, Natalia 1<br />

Poster <strong>Abstract</strong>s<br />

1 Institute of Cytology and Genetics SD RAS, Novosibirsk, Russia<br />

The sensory contact model allows the aggressive type of behavior to be<br />

formed as a result of repeated experience of victories in daily agonistic<br />

interactions in male mice. Some behavioral domains confirm the development<br />

of learned aggression in the winners similar to those in humans. The<br />

features are: repeated experience of aggression reinforced by victories;<br />

elements of learned behavior after period of confrontations; intent, measured<br />

by increase of the aggressive motivation prior agonistic confrontation;<br />

decreased emotionality. Positive fighting experience in daily social<br />

confrontations changes many characteristics of individual and social behaviors,<br />

these having been estimated in varied situations. Neurochemical<br />

data confirm the activation of brain dopaminergic systems and functional<br />

inhibition of serotonergic system in the winners under influence of repeated<br />

aggression, that create the low threshold for aggressive reaction in<br />

even weakly provoking environment. Changes in opioidergic systems form<br />

aggression abuse in male mice. Long experience of aggression is accompanied<br />

by development of abnormal and violent aggression accompanying<br />

by hyperkinetic and stereotypic reaction, hostile behavior, hostility, maniclike<br />

states, disturbances in social recognition, pronounced anxiety, addictive<br />

state etc [review, Kudryavtseva, 2006].<br />

Kudryavtseva N.N. Psychopathology of repeated aggression: a neurobiological<br />

aspect. In “Perspectives on the Psychology of Aggression” Ed. J.P.<br />

Morgan, NOVA Science Publishers, Inc. 2006. Chapter 2, pp.35-64<br />

83

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