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Program & Abstract Book - EPFL Latsis Symposium 2009

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<strong>EPFL</strong> <strong>Latsis</strong> <strong>Symposium</strong> <strong>2009</strong>: Understanding Violence<br />

P-21<br />

Poster <strong>Abstract</strong>s<br />

the structural phenotypes of<br />

persistent violence: a nipa<br />

structural mri stuDy<br />

Guidi, Raffaella; Magistretti, Pierre J.; Halfon, Olivier; Cardinaux,<br />

Jean-René<br />

1 Institute of Psychiatry, Kings College London, UK<br />

Detailed neurobiological models of reactive violence in ASPD and instrumental<br />

violence in psychopathy have emerged in the last decade. However,<br />

potential structural brain differences between psychopathic men and<br />

antisocial men who do not meet psychopathy criteria remain to be established.<br />

The Neurobiological Investigations of Persistent Aggression (NIPA)<br />

study is attempting to distinguish between these groups across multiple<br />

modalities. The current study (a work in progress) examined the differences<br />

in grey matter volume between 3 groups of men matched for age<br />

and IQ: 1) violent offenders with ASPD but without psychopathy (PCL-<br />

R>25) (n=20); 2) violent offenders with ASPD and psychopathy (PCL-R<br />

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