Research Report Abstracts - Gesundheit

WPT2011, Research Report Abstracts eS927
Participants: The examination subjects were the right knee
joints of 15 healthy volunteers who provided informed consent
(eight males, seven females; mean age: 24.3-year-old).
Methods: Traction at 100 N and 200 N was applied to the
right lower thighs at seven knee joint angles (the fully
extended position, 25 ◦ ,35 ◦ ,45 ◦ ,55 ◦ ,70 ◦ , and 90 ◦ ), and the
joint space widths obtained from ultrasonographic images (B
mode) of the knee joint before traction and 10 seconds after
the beginning of traction.
Analysis: In each experimental conditions, the separation
distance was defined as the difference between the joint space
width before traction and that during traction.
Results: The mean separation distances [mm] (standard
deviation) with traction of 200 N were, in increasing order
of the angle, 0.3 (0.4), 1.3 (0.8), 1.3 (0.7), 1.7 (1.0),
1.6 (0.9), 1.1 (0.6), and 0.7 (0.8), respectively. The mean
separation distances for 25 ◦ ,35 ◦ ,45 ◦ , and 55 ◦ were significantly
greater than that in the fully extended position
(p < 0.05), and the mean separation distances for 45 ◦ and
55 ◦ were significantly larger than that for 90 ◦ (p < 0.05).
The angle that was estimated to maximize the separation
distance from the regression formula, which shows the relation
between the joint angle and the separation distance,
y = −0.0005x 2 + 0.0502x + 0.3484, was approximately 50 ◦ .
In cases of traction at 100 N, no significant differences were
found between any of the angles (p > 0.05).
Conclusions: Collagen fibers being the main component of
ligaments and articular capsules tend to be gradually stretched
under continued addition of an external force. Taking these
characteristics into consideration, the separation distance of
the present study obtained with short duration of traction is
considered not to indicate the anti-stretch force of tissues
stretched by the traction but to mainly reflect the loose level
of periarticular tissues removed by the addition of the traction
force. Accordingly, it was demonstrated that the MLPP of
the normal knee is the flexed position at approximately 50 ◦ ,
which shows the largest separation distance, and with larger
angles than experts have previously indicated.
Implications: The findings of this study will contribute to
effective conducting of joint mobilization to the impaired
knees.
Keywords: Knee joint; Maximally loose-packed position;
Joint traction
Funding acknowledgements: None.
Ethics approval: This study was approved by the ethics
committee of Tokyo Metropolitan University.
Research Report Platform Presentation
Number: RR-PL-3524 Wednesday 22 June 16:30
RAI: Auditorium
GRADED AEROBIC EXERCISE INTERVENTION
IMPROVES VO2MAX IN EARLY ONSET TYPE 2
DIABETES
O’Hanlon D. 1 , Wanic K. 2 , Pazderska A. 3 , O’Gorman D. 4 ,
Cooper D. 4 , Collura N. 5 , Lithander F. 6 , Nolan J. 7
1Trinity College Dublin, Clinical Medicine, Dublin, Ireland,
2St. James’s Hospital, Metabolic Research Unit, Dublin,
Ireland, 3St. James Hospital, Metabolic Research Unit,
Dublin, Ireland, 4Dublin City University, Health & Human
Performance, Dublin, Ireland, 5St. James’s Hospital, Clinical
Nutrition, Dublin, Ireland, 6Trinity College Dublin,
Nutrition and Dietetics, Dublin, Ireland, 7St James Hospital,
Metabolic Research Unit, Department of Endocrinology,
Dublin, Ireland
Purpose: The prevalence of type 2 diabetes (T2DM) has
increased dramatically and it is predicted that more than 50
million Europeans will be diagnosed by 2030. At the same
time the age of diagnosis has decreased and the fastest growing
demographic are those aged between 15 and 40 years.
Earlier onset increases the patient exposure to the disease,
and therefore increases the risk of complications, particularly
cardiovascular disease. We recently reported that patients
with early onset T2DM have a blunted or absent metabolic
response to aerobic exercise, associated with abnormalities
in skeletal muscle mitochondrial proteins. The aim of this
study was to investigate the effectiveness of a graded 12-week
exercise intervention.
Relevance: Exercise has been shown to be the key intervention
in the prevention and early treatment of T2DM.
Participants: Twenty-one subjects were recruited; 6
patients with early onset T2DM (28.5 ± 1.4 years, BMI
37.5 ± 5.4 kg/meter 2 ), 7 patients with later onset T2DM
(53.3 ± 1.9 years, BMI 33.5 ± 2.5 kg/meter 2 ), and 8
young obese non-diabetic subjects (22.9 ± 2.2 years, BMI
35.6 ± 1.7 kg/meter 2 ). Subjects were sedentary and weight
stable prior to the study. The patients with diabetes were
recruited from outpatient clinics in St. James’s Hospital
Dublin, and the non-diabetic subjects were recruited using
local advertisements in Dublin City University.
Methods: The study was a longitudinal, controlled study.
Baseline testing included anthropometric measurements and
a VO2max fitness test, after which subjects began a 12-week
supervised progressive aerobic exercise intervention training
four days per week at 70% VO2max, and expending
2500 kcal per week. Supplementary VO2max tests were performed
at week 4 and week 8 of the exercise intervention, and
in the case of any increase in VO2max, the training intensity
was increased to 70% of the new VO2max. Dietary intake was
kept constant throughout and monitored using food diaries.
Testing was repeated after the intervention.