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Research Report Abstracts - Gesundheit

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WPT2011, <strong>Research</strong> <strong>Report</strong> <strong>Abstracts</strong> eS881<br />

Active Sensation Test (HASTe). All subjects underwent MRI<br />

testing that included structural and functional MRI scans in<br />

a Phillips 3 Tesla (T) scanner. A manual brush protocol was<br />

used for fMRI acquisition of perception and discrimination<br />

of stimulation to the right index finger. The superior thalamic<br />

radiations (STR) were reconstructed within the stroke<br />

subjects, using a semi-automated double ROI diffusion tractography<br />

approach.<br />

Analysis: Analysis of MRI data was done using Oxford<br />

Centre for Functional MRI of the Brain (FMRIB) Software<br />

Library (FSL). Fiber tracking was carried out in DTIstudio<br />

and was based on the fiber assignment continuous tracking<br />

(FACT) algorithm. Correlations were computed for fiber density,<br />

fMRI activation in SI and SII, and HASTe accuracy<br />

scores.<br />

Results: Brush perception in controls activated left SI and<br />

SII and right cerebellum; the stroke group activated left<br />

supramarginal gyrus, SII and precentral gyrus. Brush discrimination<br />

in controls activated a previously described<br />

network linking left SI and bilateral SII with the right paracingulate<br />

gyrus, middle frontal gyrus and precentral gyrus.<br />

Activation for the stroke group was primarily contralesional<br />

(right), located in supramarginal, paracingulate, precentral<br />

and left SII. Fiber density within the lesioned STR was diminished<br />

for all but one subject. SI activation strongly correlated<br />

to STR fiber density (r = .79, p = .02). SI and SII activation<br />

trended toward significance with HASTe scores (r −.52 and<br />

.56, respectively, p = .12).<br />

Conclusions: This study confirms the relationship between<br />

structural connectivity (STR fiber density) and functional<br />

activation in the primary sensory cortex and suggests a similar<br />

relationship between haptic sensory function and fMRI<br />

activation within SI and SII.<br />

Implications: Since sensory deficits impact motor recovery,<br />

the development of rehabilitation protocols that maximize<br />

neural plasticity within the STR and sensory cortex are<br />

needed to promote greater functional recovery.<br />

Keywords: Stroke; fMRI; Diffusion tractography<br />

Funding acknowledgements: OSUMC Neuroscience Signature<br />

Program Seed Grant, National Center for <strong>Research</strong><br />

Resources TL1 RR025753, The Wright Center of Innovation<br />

(WCI) in Biomedical Imaging at The Ohio State University,<br />

Ohio Department of Development (AGMT TECH 03-051).<br />

Ethics approval: Protocol was approved by The Ohio State<br />

University Biomedical Sciences IRB.<br />

<strong>Research</strong> <strong>Report</strong> Platform Presentation<br />

Number: RR-PL-2072 Thursday 23 June 11:30<br />

RAI: Elicium D201-202<br />

MOVING CLINICAL PRACTICE FORWARD IN<br />

CHILDREN WITH PRIMARY LANGUAGE<br />

DISORDER USING THE INTERNATIONAL<br />

CLASSIFICATION OF FUNCTION, DISABILITY<br />

AND HEALTH FRAMEWORK<br />

Nicola K., Watter P.<br />

The University of Queensland, Division of Physiotherapy,<br />

Brisbane, Australia<br />

Purpose: This audit examined the assessments used by<br />

members of the interprofessional team which provided management<br />

for children with primary language disorder (PLD).<br />

This service was provided within a school setting – The<br />

Glenleighden School (TGS) – in Brisbane, Australia which<br />

operates specifically to manage these clients. The framework<br />

provided by the International Classification of Function, Disability<br />

and Health (ICF) was used to identify the scope of<br />

assessment and where duplication of assessments and possible<br />

over-assessment may occur.<br />

Relevance: PLD is a developmental language disorder with<br />

unknown aetiology often called Specific Language Impairment<br />

in the literature, and prevalence of 7.4%. Children<br />

with PLD have a complex presentation including additional<br />

deficits in fine and gross motor performance, education<br />

and behaviour, requiring interprofessional management. This<br />

paper explores the placement, scope and overlap of the assessments<br />

used by the interprofessional team within the ICF<br />

framework, illustrating the usefulness of the ICF in guiding<br />

future assessment in this population.<br />

Participants: Files of all children (n = 119, males = 90)<br />

attending TGS between 2000 and 2008, and diagnosed with<br />

primary language disorder, were audited.<br />

Methods: The assessments used within each discipline were<br />

identified and placed within the ICF framework after discussion<br />

with relevant professionals and reference to manuals.<br />

Tests, including subtests, were organized according to ICF<br />

domains rather than discipline. To allow us to identify<br />

where tests measured similar performances, results of each<br />

assessment were audited and relationships between assessments<br />

were explored, both between and within various ICF<br />

domains.<br />

Analysis: Statistical Package for the Social Sciences program<br />

was used to compute frequencies and correlations between<br />

the assessment results. Alpha was set at p = 0.05.<br />

Results: Across disciplines, multiple and most assessments<br />

occur in the body structure and function (BSF) and activity<br />

domains (AD) with no formal assessment of participation.<br />

Some recognition of contextual factors was reported. Strong<br />

and significant correlations were found between many subtests<br />

across and within the ICF domains, for example (i)<br />

across domains: Posture and balance scores (BSF) correlated<br />

with Bruininks balance scores (AD), (r = 0.775, p = 0.00),

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