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Research Report Abstracts - Gesundheit

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eS866<br />

Analysis: We analysed the outcome data using weighted<br />

mean difference for identical outcome measures and the standardised<br />

mean difference when different measurement scales<br />

were used. We applied a random-effects meta-analysis model<br />

throughout. Where it was not possible to perform a metaanalysis<br />

due either to significant heterogeneity or a lack of<br />

evidence, we provide a narrative summary of the data for each<br />

study. The analysis was performed using RevMan5 ® .<br />

Results: Overall the meta-analysis found no evidence for the<br />

effectiveness of CBR as compared with IBR with respect to<br />

functional outcome (Standardised Mean Difference (SMD)<br />

0.09; 95% Confidence Interval (CI) −0.08 to 0.26) or quality<br />

of life (Mean Difference (MD) 1.32; 95% CI −4.30 to<br />

6.93) or carer strain (MD 0.76; 95% CI −0.19 to 1.77). Subgroup<br />

analyses at three months showed a significant effect<br />

for community-based rehabilitation over hospital/institution<br />

based rehabilitation on quality of life (MD 5.00; 95% CI<br />

0.82–9.18); however, this effect was not maintained at six<br />

months. Cost-effectiveness tended towards a cost reduction<br />

associated with community-based rehabilitation.<br />

Conclusions: Use of community-based rehabilitation may<br />

be associated with positive and negative effects. However,<br />

there is currently insufficient supporting evidence to justify<br />

the implementation of community-based rehabilitation for<br />

stroke rehabilitation. A stronger evidence base is required to<br />

adequately inform health policy decisions and guide methods<br />

of service delivery to effective improve stroke patient<br />

outcomes.<br />

Implications: RCT’s provided insufficient data to support<br />

evidence-based recommendations regarding the use of CBR<br />

over IBR on improving functional independence, quality<br />

of life, carer strain and cost effectiveness for patients with<br />

stroke. Currently inadequate evidence to support the routine<br />

implementation of CBR for the management of stroke<br />

patients with functional limitations and participation restrictions.<br />

Keywords: Community-based rehabilitation; Stroke; Systematic<br />

review<br />

Funding acknowledgements: The work was unfunded.<br />

Ethics approval: Ethics approval was not needed as it is<br />

secondary research.<br />

<strong>Research</strong> <strong>Report</strong> Platform Presentation<br />

Number: RR-PL-1438 Tuesday 21 June 16:30<br />

RAI: E106-107<br />

IS IONTOPHORESIS OF VALUE IN<br />

PHYSIOTHERAPY?<br />

Naidoo N. 1 , Naidoo R. 2<br />

1University of Cape Town, Physiotherapy, Cape Town, South<br />

Africa, 2Clairwood Hospital, Physiotherapy, Durban, South<br />

Africa<br />

Purpose: Iontophoresis is a therapeutic, non-invasive method<br />

of transdermal drug delivery which may be used to stimulate<br />

wound healing and could provide physiotherapists with<br />

an effective adjuvant treatment modality to facilitate wound<br />

care. The main aim was to investigate the effectiveness of<br />

antibiotic iontophoresis on open burn injuries of the hand on<br />

wound healing, pain inhibition and wound infection control.<br />

Relevance: Physiotherapists treat open wounds in general<br />

practice and are a vital member of the multidisciplinary<br />

wound care team. There is evidence, although dated, to support<br />

the use of iontophoresis to accelerate wound healing.<br />

Iontophoresis could enhance rehabilitation and function and<br />

provide effective adjuvant treatment for open wound injuries.<br />

Participants: 22 subjects between the ages 18 and 55 years<br />

with partial thickness open burn wounds to the hands sustained<br />

within a week of injury were included in this study.<br />

Methods: Eleven subjects were randomly assigned to the<br />

experimental group and 11 subjects were included in the<br />

control group, All participants were assessed initially and<br />

subsequently at weekly intervals where measurements of<br />

pain, bacteriology, wound size and range of motion were<br />

taken. Outcome measures included a visual analogue scale<br />

to measure pain; wound swabs were subjected to microbiology<br />

analysis, wound surface area was calculated and the<br />

range of motion at the associated joints was measured using a<br />

goniometer. All participants received mobilization exercises<br />

and standardized wound lavage and dressings. Additionally,<br />

those participants in the experimental group received antibiotic<br />

iontophoresis and those in the control group received<br />

topical antibiotic application in the wound dressings.<br />

Analysis: Descriptive statistics were used to describe the<br />

participants. Chi squared and t tests were done to compare<br />

the independent variable. A repeated measures ANOVA was<br />

used to compare the two groups over time with respect to the<br />

outcome variables.<br />

Results: There were no significant differences between the<br />

two groups at the initiation of the study. There was a trend<br />

using the ANOVA towards decreased pain in the iontophoresis<br />

group, however, this was not significant (p = 0.11). t tests<br />

calculating the wound surface area showed no significant difference<br />

(p = 0.29). Although the distribution was the same in<br />

both groups on initiation of the study, the Chi squared test<br />

showed that there were a greater number in the experimental<br />

group that had no growth of organisms (p = 0.01).

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