Research Report Abstracts - Gesundheit

WPT2011, Research Report Abstracts eS415
Participants: Consecutive sampling was used to draw
participants (n = 73) for the interviews at the study sites preoperatively.
Methods: A longitudinal pre-test post-test study utilized
interviews to collect quantitative data. Participants were
included if they were scheduled for first time unilateral (or
bilateral amputation done at the same time) lower limb amputation.
Those with an amputation as a result of traumatic or
congenital birth defects were excluded. Participants with comorbidities
that interfered with function pre-operatively were
also excluded. Institutional ethical clearance was obtained
and informed consent was obtained from participants. A
demographic questionnaire, the EQ-5D, the Modified Household
Economic and Social Status Index (HESSI) and the
Barthel Index (BI) were used to collect data. Participants
were approached preoperatively for their interviews and then
followed up three months post-operatively to establish survival/existence.
Analysis: Descriptive statistics were used. Preoperative differences
in function and quality of life were analyzed using
Wilcoxon Signed-rank test. Preoperative differences in frequencies
were analyzed using Chi square/Fischer’s exact
tests.
Results: Twenty-four participants (33%) had died. The preoperative
median Visual Analogue Scale (VAS) was 60 and
70 showing no significant difference in quality of life (QOL)
between those who survived and those who died respectively.
The preoperative median total BI score was 20 and
19 showing significantly inferior function for the deceased
(p = 0.01). The deceased were significantly older (p = 0.009)
used alcohol (p = 0.02) and smoked tobacco (p = 0.03).
Conclusions: Being older, having poorer function, being a
smoker and drinking alcohol preoperatively seem to decrease
the chance of survival following LLA in Johannesburg.
Implications: This study helped to identify the profile of
patient who are most likely not to survive three months after
a LLA. These findings will help strengthen preoperative programmes
to minimize death after a LLA especially efforts to
stress lifestyle modifications and physical fitness to promote
functional independence preoperatively.
Keywords: Lower limb amputation; Survival; Quality of life
Funding acknowledgements: We thank the Faculty
Research Fund for financial support for this study.
Ethics approval: The Human Research Ethics Committee
of the University of the Witwatersrand (clearance no.
M080422).
Research Report Poster Display
Number: RR-PO-309-5-Tue Tuesday 21 June 13:00
RAI: Exhibit Halls2&3
THE DIRECT EFFECT OF MODERATE INTENSIVE
PHYSICAL ACTIVITY ON BIOCHEMICAL
MARKERS OF BONE METABOLISM AMONG
HEALTHY YOUNG PEOPLE
Gombos G. 1 , Steinhausz V. 1 , Schmidt B. 2 , Szekeres L. 3
1University of Pécs Faculty of Health Sciences, Physiotherapy,
Zalaegerszeg, Hungary, 2University of Pécs,
Physiotherapy, Zalaegerszeg, Hungary, 3Hévíz Thermal Lake
and St. Adrew’s Rheumatism Hospital, Rheumatology, Hévíz,
Hungary
Purpose: The aim of this study is to measure if there is
any direct, detected effect of specific training programme on
biochemical markers of bone metabolism.
Relevance: It is known that the physically active lifestyle,
weight-bearing exercises are very important to establish and
maintain the optimal bone mineral density.
Participants: Total of 50 young, healthy adults (age 25 ± 2)
were included without any disease or condition of the calcium
and bone metabolism (using laboratory tests and Quantitative
Ultrasound measurement of the heel).
Methods: 15 men and 15 women carried out specific exercises
during 60 minutes conducted by physiotherapists; and
20 women performed steady walking in the same time. At
the beginning and in the end of training programs laboratory
tests were carried out to measure the level of bone-specific
alkaline phosphates (BALP) and -cross-laps values.
Analysis: Data were analysed by Wilcoxon tests applying
SPSS statistic programme.
Results: In both groups a slight, statistically not significant
decrease was detected in the value of BALP (p = 0.322 vs.
p = 0.219); the rate of decrease in the target group 3.67% vs.
7.16%). Significant decrease was detected in -cross lapsvalues
in all groups (p = 0.0066 vs. p = 0.0008). In the target
group the value of -cross laps decreased with 23.13% vs.
53.2%.
Conclusions: These results verify the direct effect of specific
physical activity on bone metabolism, independent of
the compared physical trainings. The continuation of this
study could be a same investigation with patients suffering
from osteoporosis in which the direct effect of physiotherapy
could be justified – compared with the benefits of drug
therapy.
Implications: The current study satisfied that the sufficient
intensity, extent and content of physical activity (even onetime)
can reduce the bone destruction process.
Keywords: Bone metabolism; Specific training programme;
Bone-specific alkaline phosphate
Funding acknowledgements: Tender of University of Pécs.
Ethics approval: Regional Research Ethics Committee of
Medical Centre, Hungary,Pécs, Szigeti u.12., 7624.