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Research Report Abstracts - Gesundheit

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WPT2011, <strong>Research</strong> <strong>Report</strong> <strong>Abstracts</strong> eS1319<br />

ity. Therefore to prevent from falling, it is important to assess<br />

this physical agility in elderly people.<br />

Participants: Thirty five functionally independent<br />

community-dwelling elderly people volunteered to<br />

participate in the study.<br />

Methods: Four Square Step Test (FSST) was used for a test<br />

of physical agility. The other physical motor function assessments<br />

were composed of 10 minute walking time (10MWT),<br />

Timed Up and Go test (TUG), Functional Reach test (FRT),<br />

one leg standing (OLS), lower extremity strength (LES), and<br />

Finger floor distance (FFD), were assessed.<br />

Analysis: The acquired data were analyzed using SPSS statistical<br />

software. Pearsons correlation was used to investigate<br />

the relationship between physical agility and the other physical<br />

assessments. The level of statistical significance was set<br />

at p < 0.05.<br />

Results: This study shows significant correlation FSST<br />

and LES (r = −.374, p < .027), FSST and TUG (r = .652,<br />

p < .0001), FSST and SLS (r = −.376, p < .026), and FSST<br />

and 10MWS (r = .624, p < .0001) at baseline. There were not<br />

significant relationship between FSST and FRT, FFD.<br />

Conclusions: To prevent from falling, it is very important to<br />

approach muscle strength, balance, and flexibility. However,<br />

the assessment of physical agility is also very important for<br />

the elderly people.<br />

Implications: Since there were significant correlations<br />

between FSST and LES, TUG, SLS, 10MWS, physical<br />

agility need to be assessed.<br />

Keywords: Community-dwelling elderly people; Balance;<br />

Physical agility<br />

Funding acknowledgements: This study was unfunded.<br />

Ethics approval: Subjects signed an information consent<br />

revealing all details of the study protocol, which had been<br />

approved by the ethics committee.<br />

<strong>Research</strong> <strong>Report</strong> Poster Display<br />

Number: RR-PO-209-1-Tue Tuesday 21 June 13:00<br />

RAI: Exhibit Halls2&3<br />

THETA BURST STIMULATION (TBS) IN MOTOR<br />

REHABILITATION AFTER STROKE: FINAL<br />

RESULTS FROM A RANDOMISED, DOUBLE BLIND<br />

PLACEBO-CONTROLLED CLINICAL TRIAL<br />

Wallace A. 1 , Talelli P. 1 , Cheeran B.J. 1 , Oliver R. 1 , Hoad<br />

D. 1 , Dileone M. 2 , van den Bos M. 1 , Acierno T. 2 , Gillini<br />

C. 2 , Barratt K. 3 , Boudrias M.-H. 1 , Hammerbeck U. 1 , Cloud<br />

G.C. 4 , Di Lazzaro V. 2 , Marsden J. 5 , Ward N.S. 1 ,<br />

Greenwood R.J. 3 , Rothwell J.C. 1<br />

1UCL Institute of Neurology, London, United Kingdom,<br />

2Universitá Cattolica, Institute of Neurology, Rome, Italy,<br />

3National Hospital of Neurology & Neurosurgery, London,<br />

United Kingdom, 4St Georges Healthcare NHS Trust, Department<br />

of Neurology, London, United Kingdom, 5University of<br />

Plymouth, School of Health Professions, Plymouth, United<br />

Kingdom<br />

Purpose: A single application of non-invasive brain stimulation,<br />

used to increase the excitability of the motor areas in<br />

the stroke hemisphere or to suppress interference from the<br />

intact hemisphere, can transiently improve hand function in<br />

people with chronic stroke (Talelli and Rothwell, 2006). The<br />

aim of this study was to test whether stimulation combined<br />

with physical therapy in a clinical treatment setting, would<br />

result in long-lasting clinically meaningful improvement that<br />

would be greater than improvement achieved with physical<br />

therapy alone.<br />

Relevance: Longitudinal studies of recovery after stroke<br />

suggest that approximately 50% of stroke survivors with significant<br />

initial arm paresis do not recover useful function<br />

of the limb. Advances in our understanding of the mechanisms<br />

of recovery and our ability to change cerebral cortical<br />

excitability, will result in treatment adjuncts that may enhance<br />

the effect of physical therapy.<br />

Participants: Participants (n = 41) had a single ischaemic<br />

stroke in the middle cerebral artery territory more than one<br />

year previously, and had residual weakness of the hand with<br />

some extension present at the wrist and the ability to grasp.<br />

Exclusion criteria were: intracerebral haemorrhage, severe<br />

aphasia or neglect, and contraindications to transcranial magnetic<br />

stimulation (TMS).<br />

Methods: Participants were randomized to receive excitatory<br />

theta burst stimulation (TBS) on the side of the stroke,<br />

inhibitory TBS over the intact side, or sham TBS. Groups<br />

were matched for age and function. TBS was given daily for<br />

10 working days and in all cases followed by one hour of<br />

intensity-controlled physical therapy (Wallace et al., 2010).<br />

Outcome measures were performed at baseline, them 3 and<br />

30 days after physical therapy treatment. Upper limb function<br />

was measured using the 9-hole Peg Test (9HPT) and Jebsen<br />

Taylor Test (JTT). Grip and pinch-grip strength were mea-

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