phage display protocols

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• With years of research and development, Creative Biolabs has extensive experience in phage display platform by employing various types of phage in various project objectives. In general, filamentous bacteriophages (e.g. M13) are the most popular vehicle choice for phage display and extensively used in many types of research. Meanwhile, Creative Biolabs is also an expert to provide phage display related services via either T4 or T7 phage systems, which can provide different promising alternatives by their special merits.
• Phage display has been well-recognized as a pivotal tool in immunological and cellular biological research due to its remarkable contribution to the development of new drugs and vaccines. This technology has been widely used as phage display library to select or isolate proteins, scaffolds, peptides or antibodies with high affinity and specificity for interested targets. • As one of the most successful applications, phage display technology has proved its safety and efficiency in the research and development of specific antibodies. Notably, take advantage of phage display platform based on human antibody sequences makes it available to produce fully human antibodies without the ethical and moral issues. In addition, this platform is also a wide choice for in vitro protein evolution; a typical example is the well-known antibody affinity maturation. Combine with mutagenesis and phage display technologies, phage display antibody library with the size of over 10 8 (10 16 has ever been achieved by Creative Biolabs) can be generated to screen the specific antibodies with high affinity for the development of high efficacy with low side effects antibody drugs.
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