antibody library service
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• Antibody libraries are constructed by the genomic information coding<br />
for <strong>antibody</strong> variable domains, which can be derived from B cells of<br />
immune or naïve donors. Antibodies are the first proteins which were<br />
successfully displayed on the surface of phage by fusing the coding<br />
sequence of scFv or Fab to the coat protein. Due to the smaller size,<br />
scFv libraries are genetically more stable than Fab libraries, while Fab<br />
libraries lack the tendency to form higher molecular weight species,<br />
such as dimers and trimers, which can simplify the selection and<br />
characterization. Through binding the specific target, the interest<br />
<strong>antibody</strong> can then be eluted and retrieved.
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