Revolutionary Procedure Could Turn the Page on Stem Cells

https://advancedregenmedinstitute.com/ - Doctors who enroll in stem cell therapy training courses through the Advanced Regenerative Medicine Institute (ARMI) learn cutting-edge techniques for using autologous stem cells to treat orthopedic injuries. ARMI also train doctors to use PRP therapy for both aesthetic and orthopedic applications. That being said, ARMI’s training could look radically different in the future if a revolutionary procedure developed at the Ohio State University Wexner Medical Center ever makes it past clinical trials to enter the market. https://advancedregenmedinstitute.com/ - Doctors who enroll in stem cell therapy training courses through the Advanced Regenerative Medicine Institute (ARMI) learn cutting-edge techniques for using autologous stem cells to treat orthopedic injuries. ARMI also train doctors to use PRP therapy for both aesthetic and orthopedic applications. That being said, ARMI’s training could look radically different in the future if a revolutionary procedure developed at the Ohio State University Wexner Medical Center ever makes it past clinical trials to enter the market.

06.03.2018 Views

In order to conduct ong>theong> procedure, researchers need two things: patient DNA or RNA and ong>theong> device itself, which looks like a small plastic chip. The biologic material is harvested from ong>theong> patient being treated, ong>theong>n processed and loaded onto ong>theong> chip. The chip is ong>theong>n placed at ong>theong> site of ong>theong> injury. Researchers apply an electric current that immediately sends ong>theong> biologic material through ong>theong> chip and into ong>theong> tissue underneath. The nanotransfection process takes less than a second. The injected DNA or RNA material ong>theong>n immediately goes to work to reprogram ong>theong> stem cells it comes in contact with. Those stem cells will grow into whatever kind of tissue was programmed into ong>theong>m by way of ong>theong> DNA or RNA. Success in Laboratory Mice Researchers have yet to test ong>theong> procedure on human subjects. However, ong>theong>y have tested it on laboratory mice with remarkable success. A video produced by ong>theong> researchers shows one particular mouse with significant damage to one of its legs. Scans showed that underneath ong>theong> surface, ong>theong>re was very little blood flow to ong>theong> injury site, thus inhibiting healing. After treatment, blood flow was restored and ong>theong> leg healed on its own without any pharmacological intervention. In anoong>theong>r experiment, researchers were able to reprogram skin cells to grow into brain cells. The new cells were transplanted into ong>theong> brain of a laboratory mice with blocked middle cerebral arteries. Essentially, ong>theong> mice had all suffered a stroke. Their brains were restored to normal function within a matter of weeks. To say this breakthrough is exciting does not truly convey ong>theong> importance of what we’re talking about here. If this new reprogramming procedure proves effective in human patients, we could be on ong>theong> verge of a set of treatments that would completely eliminate ong>theong> need for pharmaceutical ong>theong>rapies, surgeries, and oong>theong>r procedures. Hopefully, we will be adding ong>theong> technique to our core set of stem cell training courses at some point in ong>theong> future. Wouldn’t that be incredible? Sources: Medical News Today – http://www.medicalnewstoday.com/articles/318841.php

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like a small plastic chip. The biologic material is harvested from <str<strong>on</strong>g>the</str<strong>on</strong>g> patient being treated, <str<strong>on</strong>g>the</str<strong>on</strong>g>n processed and loaded<br />

<strong>on</strong>to <str<strong>on</strong>g>the</str<strong>on</strong>g> chip. The chip is <str<strong>on</strong>g>the</str<strong>on</strong>g>n placed at <str<strong>on</strong>g>the</str<strong>on</strong>g> site of <str<strong>on</strong>g>the</str<strong>on</strong>g> injury. Researchers apply an electric current that immediately<br />

sends <str<strong>on</strong>g>the</str<strong>on</strong>g> biologic material through <str<strong>on</strong>g>the</str<strong>on</strong>g> chip and into <str<strong>on</strong>g>the</str<strong>on</strong>g> tissue underneath. The nanotransfecti<strong>on</strong> process takes less<br />

than a sec<strong>on</strong>d.<br />

The injected DNA or RNA material <str<strong>on</strong>g>the</str<strong>on</strong>g>n immediately goes to work to reprogram <str<strong>on</strong>g>the</str<strong>on</strong>g> stem cells it comes in c<strong>on</strong>tact with.<br />

Those stem cells will grow into whatever kind of tissue was programmed into <str<strong>on</strong>g>the</str<strong>on</strong>g>m by way of <str<strong>on</strong>g>the</str<strong>on</strong>g> DNA or RNA.<br />

Success in Laboratory Mice<br />

Researchers have yet to test <str<strong>on</strong>g>the</str<strong>on</strong>g> procedure <strong>on</strong> human subjects. However, <str<strong>on</strong>g>the</str<strong>on</strong>g>y have tested it <strong>on</strong> laboratory mice with<br />

remarkable success. A video produced by <str<strong>on</strong>g>the</str<strong>on</strong>g> researchers shows <strong>on</strong>e particular mouse with significant damage to <strong>on</strong>e of<br />

its legs. Scans showed that underneath <str<strong>on</strong>g>the</str<strong>on</strong>g> surface, <str<strong>on</strong>g>the</str<strong>on</strong>g>re was very little blood flow to <str<strong>on</strong>g>the</str<strong>on</strong>g> injury site, thus inhibiting<br />

healing. After treatment, blood flow was restored and <str<strong>on</strong>g>the</str<strong>on</strong>g> leg healed <strong>on</strong> its own without any pharmacological<br />

interventi<strong>on</strong>.<br />

In ano<str<strong>on</strong>g>the</str<strong>on</strong>g>r experiment, researchers were able to reprogram skin cells to grow into brain cells. The new cells were<br />

transplanted into <str<strong>on</strong>g>the</str<strong>on</strong>g> brain of a laboratory mice with blocked middle cerebral arteries. Essentially, <str<strong>on</strong>g>the</str<strong>on</strong>g> mice had all<br />

suffered a stroke. Their brains were restored to normal functi<strong>on</strong> within a matter of weeks.<br />

To say this breakthrough is exciting does not truly c<strong>on</strong>vey <str<strong>on</strong>g>the</str<strong>on</strong>g> importance of what we’re talking about here. If this new<br />

reprogramming procedure proves effective in human patients, we could be <strong>on</strong> <str<strong>on</strong>g>the</str<strong>on</strong>g> verge of a set of treatments that<br />

would completely eliminate <str<strong>on</strong>g>the</str<strong>on</strong>g> need for pharmaceutical <str<strong>on</strong>g>the</str<strong>on</strong>g>rapies, surgeries, and o<str<strong>on</strong>g>the</str<strong>on</strong>g>r procedures. Hopefully, we will<br />

be adding <str<strong>on</strong>g>the</str<strong>on</strong>g> technique to our core set of stem cell training courses at some point in <str<strong>on</strong>g>the</str<strong>on</strong>g> future. Wouldn’t that be<br />

incredible?<br />

Sources:<br />

<br />

Medical News Today – http://www.medicalnewstoday.com/articles/318841.php

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